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James Dooley
James Dooley
Verified email at babraham.ac.uk
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Year
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
JD Fontenot, JP Rasmussen, LM Williams, JL Dooley, AG Farr, ...
Immunity 22 (3), 329-341, 2005
29182005
Developmental regulation of Foxp3 expression during ontogeny
JD Fontenot, JL Dooley, AG Farr, AY Rudensky
The Journal of experimental medicine 202 (7), 901-906, 2005
5792005
Histamine receptor H1–mediated sensitization of TRPV1 mediates visceral hypersensitivity and symptoms in patients with irritable bowel syndrome
MM Wouters, D Balemans, S Van Wanrooy, J Dooley, V Cibert-Goton, ...
Gastroenterology 150 (4), 875-887. e9, 2016
3492016
The cellular composition of the human immune system is shaped by age and cohabitation
EJ Carr, J Dooley, JE Garcia-Perez, V Lagou, JC Lee, C Wouters, I Meyts, ...
Nature immunology 17 (4), 461-468, 2016
3102016
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
SL Masters, V Lagou, I Jéru, PJ Baker, L Van Eyck, DA Parry, D Lawless, ...
Science translational medicine 8 (332), 332ra45-332ra45, 2016
3032016
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
W Pierson, B Cauwe, A Policheni, SM Schlenner, D Franckaert, J Berges, ...
Nature immunology 14 (9), 959-965, 2013
2502013
Notch ligands Delta1 and Jagged1 transmit distinct signals to T-cell precursors
SM Lehar, J Dooley, AG Farr, MJ Bevan
Blood 105 (4), 1440-1447, 2005
2352005
Microglia require CD4 T cells to complete the fetal-to-adult transition
E Pasciuto, OT Burton, CP Roca, V Lagou, WD Rajan, T Theys, ...
Cell 182 (3), 625-640. e24, 2020
2292020
Regulation of thymic epithelium by keratinocyte growth factor
M Erickson, S Morkowski, S Lehar, G Gillard, C Beers, J Dooley, JS Rubin, ...
Blood, The Journal of the American Society of Hematology 100 (9), 3269-3278, 2002
2092002
The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor
AS Papadopoulou, J Dooley, MA Linterman, W Pierson, O Ucar, ...
Nature immunology 13 (2), 181-187, 2012
1852012
Molecular control over thymic involution: From cytokines and microRNA to aging and adipose tissue
J Dooley, A Liston
European journal of immunology 42 (5), 1073-1079, 2012
1712012
Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation
GO Gillard, J Dooley, M Erickson, L Peltonen, AG Farr
The Journal of Immunology 178 (5), 3007-3015, 2007
1572007
The microRNA-29 family dictates the balance between homeostatic and pathological glucose handling in diabetes and obesity
J Dooley, JE Garcia-Perez, J Sreenivasan, SM Schlenner, ...
Diabetes 65 (1), 53-61, 2016
1502016
Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes
J Dooley, L Tian, S Schonefeldt, V Delghingaro-Augusto, JE Garcia-Perez, ...
Nature genetics 48 (5), 519-527, 2016
1412016
Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency
L Van Eyck, MS Hershfield, D Pombal, SJ Kelly, NJ Ganson, L Moens, ...
Journal of Allergy and Clinical Immunology 135 (1), 283-287. e5, 2015
1372015
Organization of thymic medullary epithelial heterogeneity: implications for mechanisms of epithelial differentiation
AG Farr, JL Dooley, M Erickson
Immunological reviews 189 (1), 20-27, 2002
1322002
MicroRNA-29 in the adaptive immune system: setting the threshold
A Liston, AS Papadopoulou, D Danso-Abeam, J Dooley
Cellular and Molecular Life Sciences 69, 3533-3541, 2012
1162012
Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development
A Astrakhan, M Omori, T Nguyen, S Becker-Herman, M Iseki, T Aye, ...
Nature immunology 8 (5), 522-531, 2007
1112007
Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
H Van Damme, B Dombrecht, M Kiss, H Roose, E Allen, E Van Overmeire, ...
Journal for immunotherapy of cancer 9 (2), 2021
1092021
Psychological comorbidity increases the risk for postinfectious IBS partly by enhanced susceptibility to develop infectious gastroenteritis
MM Wouters, S Van Wanrooy, A Nguyen, J Dooley, J Aguilera-Lizarraga, ...
Gut 65 (8), 1279-1288, 2016
992016
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