| Improving antibody affinity by mimicking somatic hypermutation in vitro PS Chowdhury, I Pastan Nature biotechnology 17 (6), 568, 1999 | 379 | 1999 |
| Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti … PS Chowdhury, JL Viner, R Beers, I Pastan Proceedings of the National Academy of Sciences 95 (2), 669-674, 1998 | 266 | 1998 |
| DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo JL Li, RCA Sainson, CE Oon, H Turley, R Leek, H Sheldon, E Bridges, ... Cancer research 71 (18), 6073-6083, 2011 | 257 | 2011 |
| RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA CM Sirois, T Jin, AL Miller, D Bertheloot, H Nakamura, GL Horvath, A Mian, ... Journal of Experimental Medicine 210 (11), 2447-2463, 2013 | 227 | 2013 |
| Phage display of disulfide-stabilized Fv fragments U Brinkmann, PS Chowdhury, DM Roscoe, I Pastan Journal of immunological methods 182 (1), 41-50, 1995 | 201 | 1995 |
| Identification of anti-alpha toxin monoclonal antibodies that reduce the severity of Staphylococcus aureus dermonecrosis and exhibit a correlation between affinity and potency C Tkaczyk, L Hua, R Varkey, Y Shi, L Dettinger, R Woods, A Barnes, ... Clin. Vaccine Immunol. 19 (3), 377-385, 2012 | 143 | 2012 |
| Immunotoxins with increased activity against epidermal growth factor receptor vIII-expressing cells produced by antibody phage display R Beers, P Chowdhury, D Bigner, I Pastan Clinical Cancer Research 6 (7), 2835-2843, 2000 | 133 | 2000 |
| Improving target cell specificity using a novel monovalent bispecific IgG design Y Mazor, V Oganesyan, C Yang, A Hansen, J Wang, H Liu, ... MAbs 7 (2), 377-389, 2015 | 124 | 2015 |
| S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo B Chen, AL Miller, M Rebelatto, Y Brewah, DC Rowe, L Clarke, ... PLoS One 10 (2), e0115828, 2015 | 109 | 2015 |
| Tailor-made antibody therapeutics PS Chowdhury, H Wu Methods 36 (1), 11-24, 2005 | 100 | 2005 |
| Insights into the molecular basis of a bispecific antibody's target selectivity Y Mazor, A Hansen, C Yang, PS Chowdhury, J Wang, G Stephens, H Wu, ... MAbs 7 (3), 461-469, 2015 | 79 | 2015 |
| Improved stability and yield of a Fv-toxin fusion protein by computer design and protein engineering of the Fv PS Chowdhury, G Vasmatzis, R Beers, B Lee, I Pastan Journal of molecular biology 281 (5), 917-928, 1998 | 75 | 1998 |
| Engineering hot spots for affinity enhancement of antibodies PS Chowdhury Recombinant Antibodies for Cancer Therapy, 179-196, 2003 | 71 | 2003 |
| Target-Agnostic Identification of Functional Monoclonal Antibodies Against Klebsiella pneumoniae Multimeric MrkA Fimbrial Subunit Q Wang, C Chang, M Pennini, M Pelletier, S Rajan, J Zha, Y Chen, ... The Journal of infectious diseases 213 (11), 1800-1808, 2016 | 66 | 2016 |
| Anti-mesothelin antibodies having high binding affinity I Pastan, PS Chowdhury US Patent 7,081,518, 2006 | 64 | 2006 |
| Isolation of anti-mesothelin antibodies from a phage display library PS Chowdhury, K Chang, I Pastan Molecular immunology 34 (1), 9-20, 1997 | 58 | 1997 |
| Targeting alpha toxin and ClfA with a multimechanistic monoclonal-antibody-based approach for prophylaxis of serious Staphylococcus aureus disease C Tkaczyk, MM Hamilton, A Sadowska, Y Shi, CS Chang, P Chowdhury, ... MBio 7 (3), e00528-16, 2016 | 54 | 2016 |
| Modified polypeptides for bispecific antibody scaffolds PS Chowdhury, V Oganesyan, Y Mazor, N Dimasi | 45 | 2013 |
| Antibodies, including Fv molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use IH Pastan, PS Chowdhury US Patent 7,368,110, 2008 | 44 | 2008 |
| Cloning and expression of the recombinant FAb fragment of monoclonal antibody K1 that reacts with mesothelin present on mesotheliomas and ovarian cancers U Brinkmann, K Webber, A Di Carlo, R Beers, P Chowdhury, K Chang, ... International journal of cancer 71 (4), 638-644, 1997 | 36 | 1997 |
