New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model AB Kleist, AE Getschman, JJ Ziarek, AM Nevins, PA Gauthier, A Chevigné, ... Biochemical pharmacology 114, 53-68, 2016 | 140 | 2016 |
Function, diversity and therapeutic potential of the N-terminal domain of human chemokine receptors M Szpakowska, V Fievez, K Arumugan, N Van Nuland, JC Schmit, ... Biochemical pharmacology 84 (10), 1366-1380, 2012 | 108 | 2012 |
The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides M Meyrath, M Szpakowska, J Zeiner, L Massotte, MP Merz, T Benkel, ... Nature communications 11 (1), 3033, 2020 | 91 | 2020 |
The distinct roles of CXCR3 variants and their ligands in the tumor microenvironment N Reynders, D Abboud, A Baragli, MZ Noman, B Rogister, SP Niclou, ... Cells 8 (6), 613, 2019 | 77 | 2019 |
Different contributions of chemokine N‐terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3 M Szpakowska, AM Nevins, M Meyrath, D Rhainds, T D'huys, ... British journal of pharmacology 175 (9), 1419-1438, 2018 | 55 | 2018 |
Assessment of biased agonism among distinct synthetic cannabinoid receptor agonist scaffolds E Wouters, J Walraed, MJ Robertson, M Meyrath, M Szpakowska, ... ACS pharmacology & translational science 3 (2), 285-295, 2019 | 49 | 2019 |
Human herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7 M Szpakowska, N Dupuis, A Baragli, M Counson, J Hanson, J Piette, ... Biochemical Pharmacology 114, 14-21, 2016 | 46 | 2016 |
Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and … M Szpakowska, M Meyrath, N Reynders, M Counson, J Hanson, ... Biochemical Pharmacology 153, 299-309, 2018 | 36 | 2018 |
vCCL2/vMIP-II, the viral master KEYmokine M Szpakowska, A Chevigné Journal of Leucocyte Biology 99 (6), 893-900, 2016 | 35 | 2016 |
Activation of the orphan G protein–coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment N Dupuis, C Laschet, D Franssen, M Szpakowska, J Gilissen, P Geubelle, ... Molecular Pharmacology 91 (6), 595-608, 2017 | 31 | 2017 |
Closing the ring: a fourth extracellular loop in chemokine receptors M Szpakowska, DP Bercoff, A Chevigné Science signaling 7 (341), pe21-pe21, 2014 | 31 | 2014 |
The diverse and complex roles of atypical chemokine receptors in cancer: From molecular biology to clinical relevance and therapy E Sjöberg, M Meyrath, A Chevigné, A Östman, M Augsten, M Szpakowska Advances in Cancer Research 145, 99-138, 2020 | 30 | 2020 |
CXCL10 is an agonist of the CC family chemokine scavenger receptor ACKR2/D6 A Chevigné, B Janji, M Meyrath, N Reynders, G D’uonnolo, T Uchański, ... Cancers 13 (5), 1054, 2021 | 29 | 2021 |
Neutralising properties of peptides derived from CXCR4 extracellular loops towards CXCL12 binding and HIV-1 infection A Chevigné, V Fievez, M Szpakowska, A Fischer, M Counson, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (5), 1031-1041, 2014 | 27 | 2014 |
CXCL14 preferentially synergizes with homeostatic chemokine receptor systems A Kouzeli, PJ Collins, M Metzemaekers, M Meyrath, M Szpakowska, ... Frontiers in immunology 11, 561404, 2020 | 26 | 2020 |
Aurora A plays a dual role in migration and survival of human glioblastoma cells according to the CXCL12 concentration E Willems, M Dedobbeleer, M Digregorio, A Lombard, N Goffart, ... Oncogene 38 (1), 73-87, 2019 | 26 | 2019 |
Systematic reassessment of chemokine-receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL22 M Meyrath, N Reynders, T Uchański, A Chevigné, M Szpakowska Journal of Leucocyte Biology 109 (2), 373-376, 2021 | 22 | 2021 |
Atypical opioid receptors: unconventional biology and therapeutic opportunities CB Palmer, M Meyrath, M Canals, E Kostenis, A Chevigné, ... Pharmacology & therapeutics 233, 108014, 2022 | 19 | 2022 |
CXCR4-binding positron emission tomography tracers link monocyte recruitment and endothelial injury in murine atherosclerosis O Baba, LH Huang, A Elvington, M Szpakowska, D Sultan, GS Heo, ... Arteriosclerosis, thrombosis, and vascular biology 41 (2), 822-836, 2021 | 19 | 2021 |
The natural analgesic conolidine targets the newly identified opioid scavenger ACKR3/CXCR7 M Szpakowska, AM Decker, M Meyrath, CB Palmer, BE Blough, ... Signal Transduction and Targeted Therapy 6 (1), 209, 2021 | 18 | 2021 |