Kalet Leon Monzon
Kalet Leon Monzon
Center of Molecular Immunology, Habana, Cuba
Verified email at cim.sld.cu
TitleCited byYear
When three is not a crowd: a Crossregulation Model of the dynamics and repertoire selection of regulatory CD4+ T cells
J Carneiro, K Leon, Í Caramalho, C Van Den Dool, R Gardner, V Oliveira, ...
Immunological reviews 216 (1), 48-68, 2007
882007
Modelling T-cell-mediated suppression dependent on interactions in multicellular conjugates
K Leon, R Perez, A Lage, J Carneiro
Journal of Theoretical Biology 207 (2), 231-254, 2000
752000
Tolerance and immunity in a mathematical model of T-cell mediated suppression
K León, A Lage, J Carneiro
Journal of theoretical biology 225 (1), 107-126, 2003
702003
A general mathematical framework to model generation structure in a population of asynchronously dividing cells
K León, J Faro, J Carneiro
Journal of theoretical biology 229 (4), 455-476, 2004
692004
Immunological self-tolerance: Lessons from mathematical modeling
J Carneiro, T Paixão, D Milutinovic, J Sousa, K Leon, R Gardner, J Faro
Journal of Computational and Applied Mathematics 184 (1), 77-100, 2005
562005
Human IL-2 mutein with higher antitumor efficacy than wild type IL-2
T Carmenate, A Pacios, M Enamorado, E Moreno, K Garcia-Martínez, ...
The Journal of Immunology 190 (12), 6230-6238, 2013
532013
Autoimmunization to epidermal growth factor, a component of the immunological homunculus
G Gonzalez, E Montero, K Leon, IR Cohen, A Lage
Autoimmunity reviews 1 (1-2), 89-95, 2002
422002
Inverse correlation between the incidences of autoimmune disease and infection predicted by a model of T cell mediated tolerance
K León, J Faro, A Lage, J Carneiro
Journal of autoimmunity 22 (1), 31-42, 2004
352004
Geometric and chemical patterns of interaction in protein–ligand complexes and their application in docking
E Moreno, K León
Proteins: Structure, Function, and Bioinformatics 47 (1), 1-13, 2002
302002
How regulatory CD25+ CD4+ T cells impinge on tumor immunobiology: the differential response of tumors to therapies
K Leon, K Garcia, J Carneiro, A Lage
The Journal of Immunology 179 (9), 5659-5668, 2007
292007
How regulatory CD25+ CD4+ T cells impinge on tumor immunobiology? On the existence of two alternative dynamical classes of tumors
K Leon, K Garcia, J Carneiro, A Lage
Journal of theoretical biology 247 (1), 122-137, 2007
292007
Three-cell interactions in T cell-mediated suppression? A mathematical analysis of its quantitative implications
K León, R Peréz, A Lage, J Carneiro
The journal of immunology 166 (9), 5356-5365, 2001
272001
Therapeutic approaches to target cancer stem cells
A Diaz, K Leon
Cancers 3 (3), 3331-3352, 2011
252011
Deciphering the molecular bases of the biological effects of antibodies against Interleukin-2: a versatile platform for fine epitope mapping
G Rojas, A Pupo, K Leon, J Avellanet, T Carmenate, S Sidhu
Immunobiology 218 (1), 105-113, 2013
212013
Computational proteomics pitfalls and challenges: HavanaBioinfo 2012 workshop report
Y Perez-Riverol, H Hermjakob, O Kohlbacher, L Martens, D Creasy, J Cox, ...
Journal of proteomics 87, 134-138, 2013
202013
Modeling the role of IL-2 in the interplay between CD4+ helper and regulatory T cells: assessing general dynamical properties
K García-Martínez, K León
Journal of theoretical biology 262 (4), 720-732, 2010
202010
Natural and induced tolerance in an immune network model
K León, J Carneiro, R Peréz, E Montero, A Lage
Journal of theoretical biology 193 (3), 519-534, 1998
181998
IL-2 derivative polypeptides
KL Monzón, TC Portilla, SP Rodriguez, NME Escalona, ABL Dávila
US Patent 9,206,243, 2015
162015
Modeling the role of IL2 in the interplay between CD4+ helper and regulatory T cells: studying the impact of IL2 modulation therapies
K García-Martínez, K León
International immunology 24 (7), 427-446, 2012
162012
Mathematical models of the impact of IL2 modulation therapies on T cell dynamics
K León, K Garcia-Martinez, T Carmenate
Frontiers in immunology 4, 439, 2013
122013
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