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Young Joo Sun
Young Joo Sun
Instructor, Byers Eye Institute at Stanford University
Bestätigte E-Mail-Adresse bei stanford.edu
Titel
Zitiert von
Zitiert von
Jahr
Distinct roles for conformational dynamics in protein-ligand interactions
X Liu, DC Speckhard, TR Shepherd, YJ Sun, SR Hengel, L Yu, CA Fowler, ...
Structure 24 (12), 2053-2066, 2016
302016
Structure-based phylogeny identifies avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice
YJ Sun, G Velez, DE Parsons, K Li, ME Ortiz, S Sharma, PB McCray, ...
The Journal of Clinical Investigation 131 (10), 2021
242021
SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility
S Awadia, F Huq, TR Arnold, SM Goicoechea, YJ Sun, T Hou, ...
Journal of Cell Biology 218 (8), 2699-2725, 2019
232019
Structural insights into the unique activation mechanisms of a non-classical calpain and its disease-causing variants
G Velez, YJ Sun, S Khan, J Yang, J Herrmann, T Chemudupati, ...
Cell reports 30 (3), 881-892. e5, 2020
192020
A simple PB/LIE free energy function accurately predicts the peptide binding specificity of the Tiam1 PDZ domain
N Panel, YJ Sun, EJ Fuentes, T Simonson
Frontiers in molecular biosciences 4, 65, 2017
162017
An intravitreal implant injection method for sustained drug delivery into mouse eyes
YJ Sun, CH Lin, MR Wu, SH Lee, J Yang, CR Kunchur, EM Mujica, ...
Cell reports methods 1 (8), 2021
142021
Peptidomimetics Therapeutics for Retinal Disease
DE Parsons, SH Lee, YJ Sun, G Velez, AG Bassuk, M Smith, VB Mahajan
Biomolecules 11 (3), 339, 2021
112021
Liquid-biopsy proteomics combined with AI identifies cellular drivers of eye aging and disease in vivo
J Wolf, DK Rasmussen, YJ Sun, JT Vu, E Wang, C Espinosa, F Bigini, ...
Cell 186 (22), 4868-4884. e12, 2023
102023
A physics-based energy function allows the computational redesign of a PDZ domain
V Opuu, YJ Sun, T Hou, N Panel, EJ Fuentes, T Simonson
Scientific Reports 10 (1), 11150, 2020
72020
Calpains as mechanistic drivers and therapeutic targets for ocular disease
JT Vu, E Wang, J Wu, YJ Sun, G Velez, AG Bassuk, SH Lee, VB Mahajan
Trends in molecular medicine 28 (8), 644-661, 2022
62022
Expanding the phenotype of TTLL5-associated retinal dystrophy: a case series
JK Oh, JG Vargas Del Valle, JR Lima de Carvalho Jr, YJ Sun, SR Levi, ...
Orphanet journal of rare diseases 17 (1), 146, 2022
42022
Novel mutations in the 3-box motif of the BACK domain of KLHL7 associated with nonsyndromic autosomal dominant retinitis pigmentosa
JK Oh, JR Lima de Carvalho, YJ Sun, S Ragi, J Yang, SR Levi, J Ryu, ...
Orphanet journal of rare diseases 14, 1-10, 2019
42019
Unleashing the potential of CRISPR multiplexing: Harnessing Cas12 and Cas13 for precise gene modulation in eye diseases
F Bigini, SH Lee, YJ Sun, Y Sun, VB Mahajan
Vision Research 213, 108317, 2023
32023
Conjunctival Swabs Reveal Higher Detection Rate Compared to Schirmer Strips for SARS-CoV-2 RNA Detection in Tears of Hospitalized COVID-19 Patients
LE Sabage, YJ Sun, J Wolf, J Sabage, A Mazzo, CF Santos, VB Mahajan, ...
Journal of Clinical Medicine 11 (23), 6929, 2022
32022
A protocol to inject ocular drug implants into mouse eyes
CH Lin, YJ Sun, SH Lee, EM Mujica, CR Kunchur, MR Wu, J Yang, ...
STAR protocols 3 (1), 101143, 2022
32022
TMPRSS2 structure-phylogeny repositions Avoralstat for SARS-CoV-2 prophylaxis in mice
Y Joo Sun, G Velez, D Parsons, K Li, M Ortiz, S Sharma, PB McCray Jr, ...
bioRxiv, 2021.01. 04.425289, 2021
32021
New COL6A6 Variant Causes Autosomal Dominant Retinitis Pigmentosa in a Four-Generation Family
V Vaclavik, L Tiab, YJ Sun, VB Mahajan, A Moulin, N Allaman-Pillet, ...
Investigative Ophthalmology & Visual Science 63 (3), 23-23, 2022
22022
Crystal Structure of The Human G267s Calpain-5 Protease Core Domain and Its Use in Rational Drug Design for Identifying Inhibitors of Calpain-5
V Mahajan, YJ Sun, G Velez, D Parsons
US Patent App. 18/030,046, 2024
2024
Macular dystrophy in Kabuki syndrome due to de novo KMT2D variants: refining the phenotype with multimodal imaging and follow-up over 10 years: insight into pathophysiology
V Vaclavik, A Navarro, A Jacot-Guillarmod, A Bottani, YJ Sun, JA Franco, ...
Graefe's Archive for Clinical and Experimental Ophthalmology, 1-8, 2024
2024
Protocol to quantify enzymatic effects on vitreous liquefaction in porcine eyes using a transwell-plate system
J Wolf, LE Sabage, YJ Sun, VB Mahajan
STAR protocols 3 (4), 101754, 2022
2022
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