| Structural characterization of a human Fc fragment engineered for lack of effector functions V Oganesyan, C Gao, L Shirinian, H Wu, WF Dall'Acqua Acta Crystallographica Section D: Biological Crystallography 64 (6), 700-704, 2008 | 260 | 2008 |
| Structural insights into neonatal Fc receptor-based recycling mechanisms V Oganesyan, MM Damschroder, KE Cook, Q Li, C Gao, H Wu, ... Journal of Biological Chemistry 289 (11), 7812-7824, 2014 | 245 | 2014 |
| The crystal structure of the endothelial protein C receptor and a bound phospholipid V Oganesyan, N Oganesyan, S Terzyan, D Qu, Z Dauter, NL Esmon, ... Journal of Biological Chemistry 277 (28), 24851-24854, 2002 | 239 | 2002 |
| Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer L Jiang, J Huang, BW Higgs, Z Hu, Z Xiao, X Yao, S Conley, H Zhong, ... PLoS genetics 12 (4), e1005895, 2016 | 162 | 2016 |
| Structural characterization of a human Fc fragment engineered for extended serum half-life V Oganesyan, MM Damschroder, RM Woods, KE Cook, H Wu, ... Molecular immunology 46 (8-9), 1750-1755, 2009 | 129 | 2009 |
| Improving target cell specificity using a novel monovalent bispecific IgG design Y Mazor, V Oganesyan, C Yang, A Hansen, J Wang, H Liu, ... MAbs 7 (2), 377-389, 2015 | 125 | 2015 |
| pH-dependent binding engineering reveals an FcRn affinity threshold that governs IgG recycling MJ Borrok, Y Wu, N Beyaz, XQ Yu, V Oganesyan, WF Dall'Acqua, P Tsui Journal of Biological Chemistry 290 (7), 4282-4290, 2015 | 125 | 2015 |
| Molecular basis for antagonistic activity of anifrolumab, an anti-interferon–α receptor 1 antibody L Peng, V Oganesyan, H Wu, WF Dall’Acqua, MM Damschroder MAbs 7 (2), 428-439, 2015 | 116 | 2015 |
| Structural characterization of a mutated, ADCC-enhanced human Fc fragment V Oganesyan, MM Damschroder, W Leach, H Wu, WF Dall’Acqua Molecular immunology 45 (7), 1872-1882, 2008 | 111 | 2008 |
| Mechanisms of neutralization of a human anti-α-toxin antibody V Oganesyan, L Peng, MM Damschroder, L Cheng, A Sadowska, ... Journal of Biological Chemistry 289 (43), 29874-29880, 2014 | 98 | 2014 |
| A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity JL Karnell, M Albulescu, S Drabic, L Wang, R Moate, M Baca, ... Science translational medicine 11 (489), eaar6584, 2019 | 75 | 2019 |
| Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody V Oganesyan, L Peng, JS Bee, J Li, SR Perry, F Comer, L Xu, K Cook, ... Journal of Biological Chemistry 293 (22), 8439-8448, 2018 | 58 | 2018 |
| Staphylococcus aureus alpha-toxin is conserved among diverse hospital respiratory isolates collected from a global surveillance study and is neutralized by monoclonal antibody … DE Tabor, L Yu, H Mok, C Tkaczyk, BR Sellman, Y Wu, V Oganesyan, ... Antimicrobial Agents and Chemotherapy 60 (9), 5312-5321, 2016 | 57 | 2016 |
| Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates DE Tabor, V Oganesyan, AE Keller, L Yu, RE McLaughlin, E Song, ... The Journal of Infectious Diseases 218 (12), 1983-1994, 2018 | 52 | 2018 |
| Modified polypeptides for bispecific antibody scaffolds PS Chowdhury, V Oganesyan, Y Mazor, N Dimasi | 46 | 2013 |
| Crystal Structure of the “PhoU-Like” Phosphate Uptake Regulator from Aquifex aeolicus V Oganesyan, N Oganesyan, PD Adams, J Jancarik, HA Yokota, R Kim, ... Journal of bacteriology 187 (12), 4238-4244, 2005 | 45 | 2005 |
| Glycan bound to the selectin low affinity state engages Glu-88 to stabilize the high affinity state under force P Mehta-D'souza, AG Klopocki, V Oganesyan, S Terzyan, T Mather, Z Li, ... Journal of Biological Chemistry 292 (6), 2510-2518, 2017 | 40 | 2017 |
| Structure of the hypothetical protein AQ_1354 from Aquifex aeolicus V Oganesyan, D Busso, J Brandsen, S Chen, J Jancarik, R Kim, SH Kim Acta Crystallographica Section D: Biological Crystallography 59 (7), 1219-1223, 2003 | 38 | 2003 |
| Blocking endothelial protein C receptor (EPCR) accelerates thrombus development in vivo MN Centelles, C Puy, J Lopez-Sagaseta, K Fukudome, R Montes, ... Thrombosis and haemostasis 103 (06), 1239-1244, 2010 | 37 | 2010 |
| Modulation of redox potential in electron transfer proteins: Effects of complex formation on the active site microenvironment of cytochrome b 5 M Wirtz, V Oganesyan, X Zhang, J Studer, M Rivera Faraday discussions 116, 221-234, 2000 | 36 | 2000 |
