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Milind D Chalishazar
Milind D Chalishazar
Verified email at merck.com
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Year
MYC drives progression of small cell lung cancer to a variant neuroendocrine subtype with vulnerability to aurora kinase inhibition
G Mollaoglu, MR Guthrie, S Böhm, J Brägelmann, I Can, PM Ballieu, ...
Cancer cell 31 (2), 270-285, 2017
4632017
MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate
AS Ireland, AM Micinski, DW Kastner, B Guo, SJ Wait, KB Spainhower, ...
Cancer cell 38 (1), 60-78. e12, 2020
2952020
Single-cell analyses reveal increased intratumoral heterogeneity after the onset of therapy resistance in small-cell lung cancer
CA Stewart, CM Gay, Y Xi, S Sivajothi, V Sivakamasundari, J Fujimoto, ...
Nature cancer 1 (4), 423-436, 2020
2632020
Inosine monophosphate dehydrogenase dependence in a subset of small cell lung cancers
F Huang, M Ni, MD Chalishazar, KE Huffman, J Kim, L Cai, X Shi, F Cai, ...
Cell metabolism 28 (3), 369-382. e5, 2018
1582018
MYC-driven small-cell lung cancer is metabolically distinct and vulnerable to arginine depletion
MD Chalishazar, SJ Wait, F Huang, AS Ireland, A Mukhopadhyay, Y Lee, ...
Clinical Cancer Research 25 (16), 5107-5121, 2019
1382019
MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer
MA Dammert, J Brägelmann, RR Olsen, S Böhm, N Monhasery, ...
Nature communications 10 (1), 3485, 2019
642019
Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer
F Huang, KE Huffman, Z Wang, X Wang, K Li, F Cai, C Yang, L Cai, ...
The Journal of clinical investigation 131 (1), 2021
352021
Sustained intratumoral activation of MM-398 results in superior activity over irinotecan demonstrated by using a systems pharmacology approach
J Kim, E Bayever, P Laivins, C Niyikiza, U Nielsen, J Fitzgerald, A Kalra, ...
Poster presented at the AACR Pancreatic Cancer Symposium, 2012
152012
Evaluating determinants for enhanced activity of MM-398/PEP02; a novel nanotherapeutic encapsulation of irinotecan (CPT-11)
A Kalra, S Klinz, N Paz, J Kim, M Chalishazar, D Drummond, D Kirpotin, ...
Cancer Research 72 (8_Supplement), 5696-5696, 2012
92012
Abstract A6: Sustained intratumoral activation of MM-398 results in superior activity over irinotecan demonstrated by using a systems pharmacology approach
J Kim, E Bayever, P Laivins, C Niyikiza, U Nielsen, J Fitzgerald, A Kalra, ...
Cancer Research 72 (13_Supplement), A6-A6, 2012
72012
Abstract A63: MM-398/PEP02, a novel liposomal formulation of irinotecan, demonstrates stromal-modifying anticancer properties.
N Paz, P Laivins, C Niyikiza, U Nielsen, J Fitzgerald, A Kalra, ...
Cancer Research 72 (14_Supplement), A63-A63, 2012
22012
Development of a bioluminescence reporter mouse model for tracking and quantifying Ly6G+ neutrophils in vivo
MD Chalishazar, N Solban, J Kopinja, D Linn, R Cristescu, H Zhou, ...
Cancer Research 82 (12_Supplement), 2455-2455, 2022
2022
Abstract PO-120: MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate
AS Ireland, AM Micinski, DW Kastner, B Guo, SJ Wait, KB Spainhower, ...
Cancer Research 80 (21_Supplement), PO-120-PO-120, 2020
2020
A08 MYC-Driven SCLC Has Unique Metabolic Vulnerabilities
SJ Wait, MD Chalishazar, F Huang, JS Bomalaski, RJ DeBerardinis, ...
Journal of Thoracic Oncology 15 (2), S14, 2020
2020
Metabolic Vulnerabilities in MYC-Driven Small Cell Lung Cancer
MD Chalishazar
The University of Utah, 2019
2019
MS32. 01 Genetic Mouse Models (GEMMS)
G Mollaoglu, M Chalishazar, F Huang, M Guthrie, S Bohm, T Sen, L Byers, ...
Journal of Thoracic Oncology 13 (10), S307-S308, 2018
2018
Abstract IA27: MYC drives molecular and therapeutically distinct subtype of SCLC
G Mollaoglu, MR Guthrie, S Bohm, J Bragelmann, MD Chalishazar, ...
Clinical Cancer Research 24 (17_Supplement), IA27-IA27, 2018
2018
Abstract A41: Sustained intratumoral activation of MM-398 results in superior activity over irinotecan demonstrated by using a systems pharmacology approach.
J Kim, E Bayever, P Laivins, C Niyikiza, U Nielsen, J Fitzgerald, A Kalra, ...
Cancer Research 72 (14_Supplement), A41-A41, 2012
2012
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