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Ashok R. Nayak
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Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM
KA Iyer, Y Hu, AR Nayak, N Kurebayashi, T Murayama, M Samsó
Science advances 6 (31), eabb2964, 2020
542020
A cryo-EM–based model of phosphorylation-and FKBP12. 6-mediated allosterism of the cardiac ryanodine receptor
S Dhindwal, J Lobo, V Cabra, DJ Santiago, AR Nayak, K Dryden, ...
Science signaling 10 (480), eaai8842, 2017
472017
Ca2+ inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM
AR Nayak, M Samsó
Elife 11, e75568, 2022
112022
Structure of Leishmania donovani coronin coiled coil domain reveals an antiparallel 4 helix bundle with inherent asymmetry
AR Nayak, SS Karade, VK Srivastava, AK Rana, CM Gupta, ...
Journal of Structural Biology 195 (1), 129-138, 2016
72016
Molecular and structural analysis of a mechanical transition of helices in the L. donovani coronin coiled-coil domain
SS Karade, A Ansari, VK Srivastava, AR Nayak, JV Pratap
International journal of biological macromolecules 143, 785-796, 2020
52020
Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli
AR Nayak, PK Singh, J Zhao, M Samso, MS Donnenberg
mBio, 2022
32022
Purification of recombinant wild type and mutant ryanodine receptors expressed in HEK293 cells
Y Hu, KA Iyer, AR Nayak, N Kurebayashi, T Murayama, M Samsó
Bio-protocol 11 (15), e4112-e4112, 2021
32021
Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor
AR Nayak, W Rangubpit, AH Will, Y Hu, P Castro-Hartmann, JJ Lobo, ...
Nature Communications, In press (accepted manuscript), 2024
2024
Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor
AR Nayak, W Rangubpit, AH Will, Y Hu, P Castro-Hartmann, JJ Lobo, ...
bioRxiv, 2024.02. 16.580716, 2024
2024
Structural basis for DNA proofreading
G Buchel, AR Nayak, K Herbine, A Sarfallah, VO Sokolova, ...
Nature Communications 14 (1), 8501, 2023
2023
High-resolution cryo-EM structures of the magnesium-inhibited and calcium-inactivated RyR1
AR Nayak, W Rangubpit, AH Will, Y Hu, K Iyer, P Castro-Hartmann, ...
Biophysical Journal 121 (3), 13a, 2022
2022
Phosphorylation of cardiac ryanodine receptor (RyR2): a structure-function study of phosphomimetic and phospho-null triple mutants
Y Hu, KA Iyer, AR Nayak, JM Eltit, N Kurebayashi, T Murayama, M Samso
Biophysical Journal 121 (3), 379a, 2022
2022
Cryo-Em Studies of Phosphomimetic and Phospho-Null Triple Mutants of Cardiac Ryanodine Receptor (RyR2)
Y Hu, K Iyer, AR Nayak, T Klose, JM Eltit, N Kurebayashi, T Murayama, ...
Biophysical Journal 120 (3), 239a, 2021
2021
A Cryo-EM Based Study of An Equivalent N Terminal Domain Mutation in Skeletal and Cardiac Ryanodine Receptor (RyR)
KA Iyer, Y Hu, AR Nayak, N Kurebayashi, T Murayama, M Samso
Biophysical Journal 118 (3), 567a-568a, 2020
2020
Structural Insight on the Regulation of RyR1 by Calcium and Magnesium
AR Nayak, AH Will, J Lobo, P Castro-Hartmann, M Samso
Biophysical Journal 118 (3), 34a, 2020
2020
A Cryo-EM Based Study of a Mutant Cardiac Ryanodine Receptor (RyR2)
KA Iyer, AR Nayak, T Murayama, N Kurebayashi, M Samso
Biophysical Journal 116 (3), 42a, 2019
2019
Structural Modulation of RyR1 by MgATP and Free Mg2+ in Lipid Membrane using CryoEM
AR Nayak, AH Will, J Lobo, PC Hartmann, M Samso
Biophysical Journal 116 (3), 183a, 2019
2019
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Articles 1–17