| From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations G Veit, RG Avramescu, AN Chiang, SA Houck, Z Cai, KW Peters, JS Hong, ... Molecular biology of the cell 27 (3), 424-433, 2016 | 579 | 2016 |
| VX-809 corrects folding defects in cystic fibrosis transmembrane conductance regulator protein through action on membrane-spanning domain 1 HY Ren, DE Grove, O De La Rosa, SA Houck, P Sopha, F Van Goor, ... Molecular biology of the cell 24 (19), 3016-3024, 2013 | 321 | 2013 |
| Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHR SA Houck, HY Ren, VJ Madden, JN Bonner, MP Conlin, JA Janovick, ... Molecular cell 54 (1), 166-179, 2014 | 170 | 2014 |
| Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein ND Camp, RG James, DW Dawson, F Yan, JM Davison, SA Houck, ... Journal of Biological Chemistry 287 (9), 6539-6550, 2012 | 136 | 2012 |
| Interactive sequences in the stress protein and molecular chaperone human αB crystallin recognize and modulate the assembly of filaments JG Ghosh, SA Houck, JI Clark The international journal of biochemistry & cell biology 39 (10), 1804-1815, 2007 | 86 | 2007 |
| Interactive domains in the molecular chaperone human αB crystallin modulate microtubule assembly and disassembly JG Ghosh, SA Houck, JI Clark PLoS One 2 (6), e498, 2007 | 77 | 2007 |
| Cellular responses to misfolded proteins and protein aggregates SA Houck, S Singh, DM Cyr Ubiquitin Family Modifiers and the Proteasome: Reviews and Protocols, 455-461, 2012 | 62 | 2012 |
| Mechanisms for quality control of misfolded transmembrane proteins SA Houck, DM Cyr Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (4), 1108-1114, 2012 | 60 | 2012 |
| The zebrafish lens proteome during development and aging TMS Greiling, SA Houck, JI Clark Molecular vision 15, 2313, 2009 | 60 | 2009 |
| Interactive sequences in the molecular chaperone, human αB crystallin modulate the fibrillation of amyloidogenic proteins JG Ghosh, SA Houck, JI Clark The international journal of biochemistry & cell biology 40 (5), 954-967, 2008 | 45 | 2008 |
| Dynamic subunit exchange and the regulation of microtubule assembly by the stress response protein human αB crystallin SA Houck, JI Clark PLoS One 5 (7), e11795, 2010 | 40 | 2010 |
| Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770 M Gentzsch, HY Ren, SA Houck, NL Quinney, DM Cholon, P Sopha, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (3 …, 2016 | 39 | 2016 |
| DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy L He, AS Kennedy, S Houck, A Aleksandrov, NL Quinney, A Cyr-Scully, ... Molecular Biology of the Cell 32 (7), 538-553, 2021 | 33 | 2021 |
| Multiple Sites in αB-Crystallin Modulate Its Interactions with Desmin Filaments Assembled In Vitro SA Houck, A Landsbury, JI Clark, RA Quinlan PloS one 6 (11), e25859, 2011 | 29 | 2011 |
| The function of the β3 interactive domain in the small heat shock protein and molecular chaperone, human αB crystallin JG Ghosh, MR Estrada, SA Houck, JI Clark Cell stress & chaperones 11 (2), 187, 2006 | 29 | 2006 |
| The β4-β8 groove is an ATP-interactive site in the α crystallin core domain of the small heat shock protein, human αB crystallin JG Ghosh, SA Houck, CE Doneanu, JI Clark Journal of molecular biology 364 (3), 364-375, 2006 | 24 | 2006 |
| Increased folding and channel activity of a rare cystic fibrosis mutant with CFTR modulators RA Caldwell, DE Grove, SA Houck, DM Cyr American Journal of Physiology-Lung Cellular and Molecular Physiology 301 (3 …, 2011 | 19 | 2011 |
| Compositions and Methods for Treatment of Protein Misfolding and Protein Aggregation Diseases JG Ghosh, JI Clark US Patent App. 11/718,708, 2008 | 10 | 2008 |
| Hemoglobin interactions with αB crystallin: A direct test of sensitivity to protein instability TJW Clark, SA Houck, JI Clark PLoS One 7 (7), e40486, 2012 | 6 | 2012 |
| VX-809 corrects folding defects in CFTR through action on membrane-spanning domain1 (MSD1) HY Ren, DE Grove, O De La Rosa, SA Houck, P Sopha, F Van Goor, ... Molecular Biology of the Cell, 2013 | 4 | 2013 |
