| Seven-transmembrane receptors KL Pierce, RT Premont, RJ Lefkowitz Nature reviews Molecular cell biology 3 (9), 639, 2002 | 2730 | 2002 |
| A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. A De Lean, JM Stadel, RJ Lefkowitz Journal of Biological Chemistry 255 (15), 7108-7117, 1980 | 1717 | 1980 |
| Transduction of receptor signals by ß-arrestins RJ Lefkowitz, SK Shenoy Science 308 (5721), 512-517, 2005 | 1661 | 2005 |
| Model systems for the study of seven-transmembrane-segment receptors HG Dohlman, J Thorner, MG Caron, RJ Lefkowitz Annual review of biochemistry 60 (1), 653-688, 1991 | 1551 | 1991 |
| β-Arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes LM Luttrell, S Ferguson, Y Daaka, WE Miller, S Maudsley, GJ Della Rocca, ... Science 283 (5402), 655-661, 1999 | 1537 | 1999 |
| Turning off the signal: desensitization of beta-adrenergic receptor function. WP Hausdorff, MG Caron, RJ Lefkowitz The FASEB Journal 4 (11), 2881-2889, 1990 | 1413 | 1990 |
| Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin RAF Dixon, BK Kobilka, DJ Strader, JL Benovic, HG Dohlman, T Frielle, ... Nature 321 (6065), 75, 1986 | 1402 | 1986 |
| International Union of Pharmacology nomenclature of adrenoceptors. DB Bylund, DC Eikenberg, JP Hieble, SZ Langer, RJ Lefkowitz, ... Pharmacological reviews 46 (2), 121-136, 1994 | 1384 | 1994 |
| G protein–coupled receptor kinases JA Pitcher, NJ Freedman, RJ Lefkowitz Annual review of biochemistry 67 (1), 653-692, 1998 | 1383 | 1998 |
| A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model. P Samama, S Cotecchia, T Costa, RJ Lefkowitz Journal of Biological Chemistry 268 (7), 4625-4636, 1993 | 1376 | 1993 |
| Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A Y Daaka, LM Luttrell, RJ Lefkowitz Nature 390 (6655), 88, 1997 | 1372 | 1997 |
| β-arrestins and cell signaling SM DeWire, S Ahn, RJ Lefkowitz, SK Shenoy Annu. Rev. Physiol. 69, 483-510, 2007 | 1280 | 2007 |
| G protein-coupled receptors III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization RJ Lefkowitz Journal of Biological Chemistry 273 (30), 18677-18680, 1998 | 1232 | 1998 |
| beta-Arrestin: a protein that regulates beta-adrenergic receptor function MJ Lohse, JL Benovic, J Codina, MG Caron, RJ Lefkowitz Science 248 (4962), 1547-1550, 1990 | 1184 | 1990 |
| The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals LM Luttrell, RJ Lefkowitz Journal of cell science 115 (3), 455-465, 2002 | 1169 | 2002 |
| Seven-transmembrane-spanning receptors and heart function HA Rockman, WJ Koch, RJ Lefkowitz Nature 415 (6868), 206, 2002 | 1077 | 2002 |
| An Akt/β-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior JM Beaulieu, TD Sotnikova, S Marion, RJ Lefkowitz, RR Gainetdinov, ... Cell 122 (2), 261-273, 2005 | 912 | 2005 |
| Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins RJ Lefkowitz, S Cotecchia, P Samama, T Costa Trends in pharmacological sciences 14 (8), 303-307, 1993 | 893 | 1993 |
| Chimeric alpha 2-, beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity BK Kobilka, TS Kobilka, K Daniel, JW Regan, MG Caron, RJ Lefkowitz Science 240 (4857), 1310-1316, 1988 | 873 | 1988 |
| Regulation of receptor fate by ubiquitination of activated β2-adrenergic receptor and β-arrestin SK Shenoy, PH McDonald, TA Kohout, RJ Lefkowitz Science 294 (5545), 1307-1313, 2001 | 866 | 2001 |
Jeffrey BenovicThomas Eakins Professor of Biochemistry and Molecular Biology, Thomas Jefferson UniversityVerified email at jefferson.edu
