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Motoko Y. Kimura
Motoko Y. Kimura
Verified email at chiba-u.jp
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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
JH Park, S Adoro, T Guinter, B Erman, AS Alag, M Catalfamo, MY Kimura, ...
Nature immunology 11 (3), 257-264, 2010
2952010
Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals
X Tai, B Erman, A Alag, J Mu, M Kimura, G Katz, T Guinter, T McCaughtry, ...
Immunity 38 (6), 1116-1128, 2013
2612013
T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation
M Yamashita, M Kimura, M Kubo, C Shimizu, T Tada, RM Perlmutter, ...
Proceedings of the National Academy of Sciences 96 (3), 1024-1029, 1999
2351999
Identification of a Conserved GATA3 Response Element Upstream Proximal from the Interleukin-13 Gene Locus* 210
M Yamashita, M Ukai-Tadenuma, M Kimura, M Omori, M Inami, ...
Journal of Biological Chemistry 277 (44), 42399-42408, 2002
2322002
Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci
M Yamashita, M Ukai-Tadenuma, T Miyamoto, K Sugaya, H Hosokawa, ...
Journal of Biological Chemistry 279 (26), 26983-26990, 2004
2132004
Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Vα14 natural killer T cells
J Cui, N Watanabe, T Kawano, M Yamashita, T Kamata, C Shimizu, ...
The Journal of experimental medicine 190 (6), 783-792, 1999
2101999
Regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function
YI Nigo, M Yamashita, K Hirahara, R Shinnakasu, M Inami, M Kimura, ...
Proceedings of the National Academy of Sciences 103 (7), 2286-2291, 2006
2082006
Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway
M Yamashita, R Shinnakasu, H Asou, M Kimura, A Hasegawa, ...
Journal of Biological Chemistry 280 (33), 29409-29419, 2005
1992005
Crucial role of MLL for the maintenance of memory T helper type 2 cell responses
M Yamashita, K Hirahara, R Shinnakasu, H Hosokawa, S Norikane, ...
Immunity 24 (5), 611-622, 2006
1662006
IL-7 signaling must be intermittent, not continuous, during CD8+ T cell homeostasis to promote cell survival instead of cell death
MY Kimura, LA Pobezinsky, TI Guinter, J Thomas, A Adams, JH Park, ...
Nature immunology 14 (2), 143-151, 2013
1562013
Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function
LA Pobezinsky, R Etzensperger, S Jeurling, A Alag, T Kadakia, ...
Nature immunology 16 (5), 517-524, 2015
1552015
T cell receptor–induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex
M Yamashita, M Katsumata, M Iwashima, M Kimura, C Shimizu, T Kamata, ...
The Journal of experimental medicine 191 (11), 1869-1880, 2000
1462000
The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression
T Nakayama, DJ Kasprowicz, M Yamashita, LA Schubert, G Gillard, ...
The Journal of Immunology 168 (1), 87-94, 2002
1402002
src homology 2 domain–containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation
T Kamata, M Yamashita, M Kimura, K Murata, M Inami, C Shimizu, ...
The Journal of clinical investigation 111 (1), 109-119, 2003
1352003
Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene
M Kimura, Y Koseki, M Yamashita, N Watanabe, C Shimizu, T Katsumoto, ...
Immunity 15 (2), 275-287, 2001
1332001
Lck availability during thymic selection determines the recognition specificity of the T cell repertoire
F Van Laethem, AN Tikhonova, LA Pobezinsky, X Tai, MY Kimura, ...
Cell 154 (6), 1326-1341, 2013
1152013
CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA
M Omori, M Yamashita, M Inami, M Ukai-Tadenuma, M Kimura, Y Nigo, ...
Immunity 19 (2), 281-294, 2003
1012003
Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity
C Shimizu, H Kawamoto, M Yamashita, M Kimura, E Kondou, Y Kaneko, ...
International immunology 13 (1), 105-117, 2001
1002001
CD69‐null mice protected from arthritis induced with anti‐type II collagen antibodies
K Murata, M Inami, A Hasegawa, S Kubo, M Kimura, M Yamashita, ...
International immunology 15 (8), 987-992, 2003
942003
The prominent 5d-orbital contribution to the conduction electrons in gold
A Sekiyama, J Yamaguchi, A Higashiya, M Obara, H Sugiyama, ...
New Journal of Physics 12 (4), 043045, 2010
912010
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