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Chuanjuan Tao
Chuanjuan Tao
Verified email at columbia.edu
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Year
Nucleotide analogues as inhibitors of SARS-CoV-2 polymerase, a key drug target for COVID-19
M Chien, TK Anderson, S Jockusch, C Tao, X Li, S Kumar, JJ Russo, ...
Journal of proteome research 19 (11), 4690-4697, 2020
2752020
Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array
CW Fuller, S Kumar, M Porel, M Chien, A Bibillo, PB Stranges, M Dorwart, ...
Proceedings of the National Academy of Sciences 113 (19), 5233-5238, 2016
2012016
PEG-Labeled Nucleotides and Nanopore Detection for Single Molecule DNASequencing by Synthesis
S Kumar, C Tao, M Chien, B Hellner, A Balijepalli, JWF Robertson, Z Li, ...
Scientific reports 2 (1), 1-8, 2012
1902012
A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19
S Jockusch, C Tao, X Li, TK Anderson, M Chien, S Kumar, JJ Russo, ...
Antiviral research 180, 104857, 2020
1292020
Method of preparation of nanopore and uses thereof
J Ju, S Kumar, C Tao, M Chien, JJ Russo, JJ Kasianowicz, ...
US Patent 10,246,479, 2019
123*2019
DNA sequencing by synthesis using modified nucleotides and nanopore detection
J Ju, S Kumar, Z Li, C Tao, M Chien, JJ Russo, S Kalachikov, K Shepard, ...
1162012
Nucleotide analogues as inhibitors of SARS‐CoV polymerase
J Ju, X Li, S Kumar, S Jockusch, M Chien, C Tao, I Morozova, ...
Pharmacology Research & Perspectives 8 (6), e00674, 2020
902020
Sofosbuvir terminated RNA is more resistant to SARS-CoV-2 proofreader than RNA terminated by Remdesivir
S Jockusch, C Tao, X Li, M Chien, S Kumar, I Morozova, S Kalachikov, ...
Scientific reports 10 (1), 16577, 2020
802020
In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19
CQ Sacramento, N Fintelman-Rodrigues, JR Temerozo, APD Da Silva, ...
Journal of Antimicrobial Chemotherapy 76 (7), 1874-1885, 2021
672021
Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array
PB Stranges, M Palla, S Kalachikov, J Nivala, M Dorwart, S Kumar, ...
Proceedings of the National Academy of Sciences 113 (44), E6749-E6756, 2016
642016
Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture
X Wang, CQ Sacramento, S Jockusch, OA Chaves, C Tao, ...
Communications Biology 5 (1), 154, 2022
542022
Method for detecting multiple predetermined compounds in a sample
J Ju, S Kumar, C Tao, S Kalachikov, JJ Russo
US Patent 10,732,183, 2020
482020
Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
J Ju, X Li, X Chen, Z Li, S Kumar, S Shi, C Guo, J Ren, MK Hsieh, M Chien, ...
US Patent 11,085,076, 2021
412021
Triphosphates of the two components in DESCOVY and TRUVADA are inhibitors of the SARS-CoV-2 polymerase
S Jockusch, C Tao, X Li, TK Anderson, M Chien, S Kumar, JJ Russo, ...
BioRxiv, 2020.04. 03.022939, 2020
322020
Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells
X Nguyenla, E Wehri, E Van Dis, SB Biering, LH Yamashiro, C Zhu, ...
Scientific reports 12 (1), 18506, 2022
222022
Ion sensor dna and rna sequencing by synthesis using nucleotide reversible terminators
J Ju, X Li, Z Li, S Kumar, X Chen, C Guo, S Shi, J Ren, C Tao, M Chien, ...
US Patent App. 15/777,416, 2018
152018
Identifying structural features of nucleotide analogues to overcome SARS-CoV-2 exonuclease activity
X Wang, C Tao, I Morozova, S Kalachikov, X Li, S Kumar, JJ Russo, J Ju
Viruses 14 (7), 1413, 2022
52022
DNA sequencing by synthesis using modified nucleotides and nanopore detection
J Ju, S Kumar, Z Li, C Tao, M Chien, JJ Russo, S Kalachikov, K Shepard, ...
US Patent 11,499,186, 2022
32022
Single molecule electronic multiplex SNP assay and PCR analysis
C Tao, S Kumar, M Chien, J Ju
US Patent 10,718,011, 2020
32020
Method of preparation of nanopore and uses thereof
J Ju, S Kumar, C Tao, M Chien, JJ Russo, JJ Kasianowicz, ...
US Patent 11,795,191, 2023
22023
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