Nucleotide analogues as inhibitors of SARS-CoV-2 polymerase, a key drug target for COVID-19 M Chien, TK Anderson, S Jockusch, C Tao, X Li, S Kumar, JJ Russo, ... Journal of proteome research 19 (11), 4690-4697, 2020 | 275 | 2020 |
Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array CW Fuller, S Kumar, M Porel, M Chien, A Bibillo, PB Stranges, M Dorwart, ... Proceedings of the National Academy of Sciences 113 (19), 5233-5238, 2016 | 201 | 2016 |
PEG-Labeled Nucleotides and Nanopore Detection for Single Molecule DNASequencing by Synthesis S Kumar, C Tao, M Chien, B Hellner, A Balijepalli, JWF Robertson, Z Li, ... Scientific reports 2 (1), 1-8, 2012 | 190 | 2012 |
A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19 S Jockusch, C Tao, X Li, TK Anderson, M Chien, S Kumar, JJ Russo, ... Antiviral research 180, 104857, 2020 | 129 | 2020 |
Method of preparation of nanopore and uses thereof J Ju, S Kumar, C Tao, M Chien, JJ Russo, JJ Kasianowicz, ... US Patent 10,246,479, 2019 | 123* | 2019 |
DNA sequencing by synthesis using modified nucleotides and nanopore detection J Ju, S Kumar, Z Li, C Tao, M Chien, JJ Russo, S Kalachikov, K Shepard, ... | 116 | 2012 |
Nucleotide analogues as inhibitors of SARS‐CoV polymerase J Ju, X Li, S Kumar, S Jockusch, M Chien, C Tao, I Morozova, ... Pharmacology Research & Perspectives 8 (6), e00674, 2020 | 90 | 2020 |
Sofosbuvir terminated RNA is more resistant to SARS-CoV-2 proofreader than RNA terminated by Remdesivir S Jockusch, C Tao, X Li, M Chien, S Kumar, I Morozova, S Kalachikov, ... Scientific reports 10 (1), 16577, 2020 | 80 | 2020 |
In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19 CQ Sacramento, N Fintelman-Rodrigues, JR Temerozo, APD Da Silva, ... Journal of Antimicrobial Chemotherapy 76 (7), 1874-1885, 2021 | 67 | 2021 |
Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array PB Stranges, M Palla, S Kalachikov, J Nivala, M Dorwart, S Kumar, ... Proceedings of the National Academy of Sciences 113 (44), E6749-E6756, 2016 | 64 | 2016 |
Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture X Wang, CQ Sacramento, S Jockusch, OA Chaves, C Tao, ... Communications Biology 5 (1), 154, 2022 | 54 | 2022 |
Method for detecting multiple predetermined compounds in a sample J Ju, S Kumar, C Tao, S Kalachikov, JJ Russo US Patent 10,732,183, 2020 | 48 | 2020 |
Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis J Ju, X Li, X Chen, Z Li, S Kumar, S Shi, C Guo, J Ren, MK Hsieh, M Chien, ... US Patent 11,085,076, 2021 | 41 | 2021 |
Triphosphates of the two components in DESCOVY and TRUVADA are inhibitors of the SARS-CoV-2 polymerase S Jockusch, C Tao, X Li, TK Anderson, M Chien, S Kumar, JJ Russo, ... BioRxiv, 2020.04. 03.022939, 2020 | 32 | 2020 |
Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells X Nguyenla, E Wehri, E Van Dis, SB Biering, LH Yamashiro, C Zhu, ... Scientific reports 12 (1), 18506, 2022 | 22 | 2022 |
Ion sensor dna and rna sequencing by synthesis using nucleotide reversible terminators J Ju, X Li, Z Li, S Kumar, X Chen, C Guo, S Shi, J Ren, C Tao, M Chien, ... US Patent App. 15/777,416, 2018 | 15 | 2018 |
Identifying structural features of nucleotide analogues to overcome SARS-CoV-2 exonuclease activity X Wang, C Tao, I Morozova, S Kalachikov, X Li, S Kumar, JJ Russo, J Ju Viruses 14 (7), 1413, 2022 | 5 | 2022 |
DNA sequencing by synthesis using modified nucleotides and nanopore detection J Ju, S Kumar, Z Li, C Tao, M Chien, JJ Russo, S Kalachikov, K Shepard, ... US Patent 11,499,186, 2022 | 3 | 2022 |
Single molecule electronic multiplex SNP assay and PCR analysis C Tao, S Kumar, M Chien, J Ju US Patent 10,718,011, 2020 | 3 | 2020 |
Method of preparation of nanopore and uses thereof J Ju, S Kumar, C Tao, M Chien, JJ Russo, JJ Kasianowicz, ... US Patent 11,795,191, 2023 | 2 | 2023 |