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Michael A. DeJesus
Michael A. DeJesus
Bioinformatics, Rockefeller University
Verified email at rockefeller.edu - Homepage
Title
Cited by
Cited by
Year
High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism
JE Griffin, JD Gawronski, MA DeJesus, TR Ioerger, BJ Akerley, ...
PLoS pathogens 7 (9), e1002251, 2011
11322011
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis
MA DeJesus, ER Gerrick, W Xu, SW Park, JE Long, CC Boutte, EJ Rubin, ...
MBio 8 (1), 10.1128/mbio. 02133-16, 2017
5312017
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis
MA DeJesus, ER Gerrick, W Xu, SW Park, JE Long, CC Boutte, EJ Rubin, ...
MBio 8 (1), 10.1128/mbio. 02133-16, 2017
5312017
TRANSIT-a software tool for Himar1 TnSeq analysis
MA DeJesus, C Ambadipudi, R Baker, C Sassetti, TR Ioerger
PLoS computational biology 11 (10), e1004401, 2015
1942015
Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis
B Bosch, MA DeJesus, NC Poulton, W Zhang, CA Engelhart, A Zaveri, ...
Cell 184 (17), 4579-4592. e24, 2021
1392021
A Hidden Markov Model for identifying essential and growth-defect regions in bacterial genomes from transposon insertion sequencing data
MA DeJesus, TR Ioerger
BMC bioinformatics 14, 1-12, 2013
962013
Chemical genetic interaction profiling reveals determinants of intrinsic antibiotic resistance in Mycobacterium tuberculosis
W Xu, MA DeJesus, N Rücker, CA Engelhart, MG Wright, C Healy, K Lin, ...
Antimicrobial agents and chemotherapy 61 (12), 10.1128/aac. 01334-17, 2017
932017
Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries
MA DeJesus, YJ Zhang, CM Sassetti, EJ Rubin, JC Sacchettini, ...
Bioinformatics 29 (6), 695-703, 2013
922013
Identifying Essential Genes in Mycobacterium tuberculosis by Global Phenotypic Profiling
JE Long, M DeJesus, D Ward, RE Baker, T Ioerger, CM Sassetti
Gene Essentiality: Methods and Protocols, 79-95, 2015
892015
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis
S Li, NC Poulton, JS Chang, ZA Azadian, MA DeJesus, N Ruecker, ...
Nature Microbiology 7 (6), 766-779, 2022
712022
Behavioral and transcriptomic profiling of mice null for Lphn3, a gene implicated in ADHD and addiction
CA Orsini, B Setlow, M DeJesus, S Galaviz, K Loesch, T Ioerger, D Wallis
Molecular genetics & genomic medicine 4 (3), 322-343, 2016
562016
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice
J Korte, M Alber, CM Trujillo, K Syson, H Koliwer-Brandl, R Deenen, ...
PLoS pathogens 12 (12), e1006043, 2016
462016
Statistical analysis of genetic interactions in Tn-Seq data
MA DeJesus, S Nambi, CM Smith, RE Baker, CM Sassetti, TR Ioerger
Nucleic acids research 45 (11), e93-e93, 2017
402017
Reannotation of translational start sites in the genome of Mycobacterium tuberculosis
MA DeJesus, JC Sacchettini, TR Ioerger
Tuberculosis 93 (1), 18-25, 2013
352013
Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression
S Subramaniyam, MA DeJesus, A Zaveri, CM Smith, RE Baker, S Ehrt, ...
BMC bioinformatics 20, 1-15, 2019
192019
CRISPR Interference Reveals That All-Trans-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to …
GH Babunovic, MA DeJesus, B Bosch, MR Chase, T Barbier, AK Dickey, ...
MBio 13 (1), e03683-21, 2022
172022
Normalization of transposon-mutant library sequencing datasets to improve identification of conditionally essential genes
MA DeJesus, TR Ioerger
Journal of bioinformatics and computational biology 14 (03), 1642004, 2016
172016
Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis
NC Poulton, ZA Azadian, MA DeJesus, JM Rock
Antimicrobial Agents and Chemotherapy 66 (9), e00904-22, 2022
102022
Capturing uncertainty by modeling local transposon insertion frequencies improves discrimination of essential genes
MA DeJesus, TR Ioerger
IEEE/ACM Transactions on Computational Biology and Bioinformatics 12 (1), 92-102, 2014
102014
The Mycobacterium tuberculosis transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality
A Jinich, A Zaveri, MA DeJesus, E Flores-Bautista, CM Smith, CM Sassetti, ...
bioRxiv, 2021.03. 05.434127, 2021
92021
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Articles 1–20