| Pain relief produces negative reinforcement through activation of mesolimbic reward–valuation circuitry E Navratilova, JY Xie, A Okun, C Qu, N Eyde, S Ci, MH Ossipov, T King, ... Proceedings of the National Academy of Sciences 109 (50), 20709-20713, 2012 | 327 | 2012 |
| Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance JY Xie, DS Herman, CO Stiller, LR Gardell, MH Ossipov, J Lai, F Porreca, ... Journal of Neuroscience 25 (2), 409-416, 2005 | 242 | 2005 |
| Biocompatible PEDOT: Nafion composite electrode coatings for selective detection of neurotransmitters in vivo RF Vreeland, CW Atcherley, WS Russell, JY Xie, D Lu, ND Laude, ... Analytical chemistry 87 (5), 2600-2607, 2015 | 208 | 2015 |
| Endogenous opioid activity in the anterior cingulate cortex is required for relief of pain E Navratilova, JY Xie, D Meske, C Qu, K Morimura, A Okun, N Arakawa, ... Journal of Neuroscience 35 (18), 7264-7271, 2015 | 202 | 2015 |
| Descending facilitation from the rostral ventromedial medulla maintains nerve injury-induced central sensitization LP Vera-Portocarrero, ET Zhang, MH Ossipov, JY Xie, T King, J Lai, ... Neuroscience 140 (4), 1311-1320, 2006 | 176 | 2006 |
| Evaluation of reward from pain relief E Navratilova, JY Xie, T King, F Porreca Annals of the New York Academy of Sciences 1282 (1), 1-11, 2013 | 157 | 2013 |
| Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states JW Little, A Ford, AM Symons-Liguori, Z Chen, K Janes, T Doyle, J Xie, ... Brain 138 (1), 28-35, 2015 | 153 | 2015 |
| Afferent drive elicits ongoing pain in a model of advanced osteoarthritis A Okun, P Liu, P Davis, J Ren, B Remeniuk, T Brion, MH Ossipov, J Xie, ... PAIN® 153 (4), 924-933, 2012 | 134 | 2012 |
| Ongoing pain in the MIA model of osteoarthritis P Liu, A Okun, J Ren, R Guo, MH Ossipov, J Xie, T King, F Porreca Neuroscience letters 493 (3), 72-75, 2011 | 109 | 2011 |
| Positive emotions and brain reward circuits in chronic pain E Navratilova, K Morimura, JY Xie, CW Atcherley, MH Ossipov, F Porreca Journal of Comparative Neurology 524 (8), 1646-1652, 2016 | 107 | 2016 |
| Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors W Zhang, S Gardell, D Zhang, JY Xie, RS Agnes, H Badghisi, VJ Hruby, ... Brain 132 (3), 778-787, 2009 | 107 | 2009 |
| Multiple sites and actions of gabapentin-induced relief of ongoing experimental neuropathic pain K Bannister, C Qu, E Navratilova, J Oyarzo, JY Xie, T King, AH Dickenson, ... Pain 158 (12), 2386-2395, 2017 | 92 | 2017 |
| Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention JY Xie, M De Felice, CM Kopruszinski, N Eyde, J LaVigne, B Remeniuk, ... Cephalalgia 37 (8), 780-794, 2017 | 92 | 2017 |
| Targeting TRP channels for novel migraine therapeutics G Dussor, J Yan, JY Xie, MH Ossipov, DW Dodick, F Porreca ACS chemical neuroscience 5 (11), 1085-1096, 2014 | 88 | 2014 |
| Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: a potential biomarker of efficacy JY Xie, C Qu, A Patwardhan, MH Ossipov, E Navratilova, L Becerra, ... Pain 155 (8), 1659-1666, 2014 | 83 | 2014 |
| CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide A Moutal, X Yang, W Li, KB Gilbraith, S Luo, S Cai, L François-Moutal, ... Pain 158 (12), 2301-2319, 2017 | 75 | 2017 |
| A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain ME Hildebrand, PL Smith, C Bladen, C Eduljee, JY Xie, L Chen, ... PAIN® 152 (4), 833-843, 2011 | 74 | 2011 |
| Prevention of stress-or nitric oxide donor-induced medication overuse headache by a calcitonin gene-related peptide antibody in rodents CM Kopruszinski, JY Xie, NM Eyde, B Remeniuk, S Walter, J Stratton, ... Cephalalgia 37 (6), 560-570, 2017 | 64 | 2017 |
| (S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation … A Moutal, LA Chew, X Yang, Y Wang, SK Yeon, E Telemi, S Meroueh, ... Pain 157 (7), 1448-1463, 2016 | 61 | 2016 |
| The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females Y Chen, A Moutal, E Navratilova, C Kopruszinski, X Yue, M Ikegami, ... Science translational medicine 12 (529), eaay7550, 2020 | 53 | 2020 |
