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Jonathan Snedeker
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A small-molecule inhibitor of WEE1, AZD1775, synergizes with olaparib by impairing homologous recombination and enhancing DNA damage and apoptosis in acute leukemia
TB Garcia, JC Snedeker, D Baturin, L Gardner, SP Fosmire, C Zhou, ...
Molecular cancer therapeutics 16 (10), 2058-2068, 2017
742017
Asymmetric histone inheritance via strand-specific incorporation and biased replication fork movement
M Wooten, J Snedeker, ZF Nizami, X Yang, R Ranjan, E Urban, JM Kim, ...
Nature structural & molecular biology 26 (8), 732-743, 2019
712019
Asymmetric centromeres differentially coordinate with mitotic machinery to ensure biased sister chromatid segregation in germline stem cells
R Ranjan, J Snedeker, X Chen
Cell stem cell 25 (5), 666-681. e5, 2019
592019
Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin
JM Kim, P Visanpattanasin, V Jou, S Liu, X Tang, Q Zheng, KY Li, ...
Elife 10, e69387, 2021
412021
Regulation of Drosophila germline stem cells
EW Kahney, JC Snedeker, X Chen
Current opinion in cell biology 60, 27-35, 2019
362019
The inherent asymmetry of DNA replication
J Snedeker, M Wooten, X Chen
Annual review of cell and developmental biology 33, 291-318, 2017
282017
Superresolution imaging of chromatin fibers to visualize epigenetic information on replicative DNA
M Wooten, Y Li, J Snedeker, ZF Nizami, JG Gall, X Chen
Nature protocols 15 (3), 1188-1208, 2020
192020
Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage
R Ranjan, J Snedeker, M Wooten, C Chu, S Bracero, T Mouton, X Chen
Developmental cell 57 (9), 1102-1118. e7, 2022
162022
Differential condensation of sister chromatids coordinates with Cdc6 to ensure distinct cell cycle progression in Drosophila male germline stem cell lineage
R Ranjan, J Snedeker, M Wooten, C Chu, S Bracero, T Mouton, X Chen
bioRxiv, 2021.03. 08.434490, 2021
42021
Stem cell mitotic drive ensures asymmetric epigenetic inheritance
R Ranjan, J Snedeker, X Chen
BioRxiv, 416446, 2018
22018
Unidirectional fork movement coupled with strand-specific histone incorporation ensures asymmetric histone inheritance
M Wooten, J Snedeker, Z Nizami, X Yang, R Ranjan, E Urban, JM Kim, ...
bioRxiv, 242768, 2018
22018
A single N-terminal amino acid determines the distinct roles of histones H3 and H3.3 in the Drosophila male germline stem cell lineage
C Chandrasekhara, R Ranjan, JA Urban, BEM Davis, WL Ku, J Snedeker, ...
Plos Biology 21 (5), e3002098, 2023
12023
Combined inhibition of wee1 and poly (ADP ribose) polymerase1/2 synergistically inhibits acute myeloid leukemia cells by enhancing DNA damage and the induction of apoptosis
JC Snedeker, TM Burleson, R Tibes, CC Porter
Blood 124 (21), 3621, 2014
12014
Reduced Levels of Lagging Strand Polymerases Shape Stem Cell Chromatin
J Snedeker, BEM Davis, R Ranjan, MI Wooten, J Blundon, X Chen
bioRxiv, 2024.04. 26.591383, 2024
2024
Roles of the distinct N-terminal amino acid between H3 and H3.3 in Drosophila male germline stem cell lineage
C Chandrasekhara, R Ranjan, JA Urban, WL Ku, J Snedeker, K Zhao, ...
bioRxiv, 2022.09. 03.506490, 2022
2022
On the Mechanism and Function of Asymmetric Histone Inheritance
J Snedeker
Johns Hopkins University, 2022
2022
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Articles 1–16