A small-molecule inhibitor of WEE1, AZD1775, synergizes with olaparib by impairing homologous recombination and enhancing DNA damage and apoptosis in acute leukemia TB Garcia, JC Snedeker, D Baturin, L Gardner, SP Fosmire, C Zhou, ... Molecular cancer therapeutics 16 (10), 2058-2068, 2017 | 74 | 2017 |
Asymmetric histone inheritance via strand-specific incorporation and biased replication fork movement M Wooten, J Snedeker, ZF Nizami, X Yang, R Ranjan, E Urban, JM Kim, ... Nature structural & molecular biology 26 (8), 732-743, 2019 | 71 | 2019 |
Asymmetric centromeres differentially coordinate with mitotic machinery to ensure biased sister chromatid segregation in germline stem cells R Ranjan, J Snedeker, X Chen Cell stem cell 25 (5), 666-681. e5, 2019 | 59 | 2019 |
Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin JM Kim, P Visanpattanasin, V Jou, S Liu, X Tang, Q Zheng, KY Li, ... Elife 10, e69387, 2021 | 41 | 2021 |
Regulation of Drosophila germline stem cells EW Kahney, JC Snedeker, X Chen Current opinion in cell biology 60, 27-35, 2019 | 36 | 2019 |
The inherent asymmetry of DNA replication J Snedeker, M Wooten, X Chen Annual review of cell and developmental biology 33, 291-318, 2017 | 28 | 2017 |
Superresolution imaging of chromatin fibers to visualize epigenetic information on replicative DNA M Wooten, Y Li, J Snedeker, ZF Nizami, JG Gall, X Chen Nature protocols 15 (3), 1188-1208, 2020 | 19 | 2020 |
Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage R Ranjan, J Snedeker, M Wooten, C Chu, S Bracero, T Mouton, X Chen Developmental cell 57 (9), 1102-1118. e7, 2022 | 16 | 2022 |
Differential condensation of sister chromatids coordinates with Cdc6 to ensure distinct cell cycle progression in Drosophila male germline stem cell lineage R Ranjan, J Snedeker, M Wooten, C Chu, S Bracero, T Mouton, X Chen bioRxiv, 2021.03. 08.434490, 2021 | 4 | 2021 |
Stem cell mitotic drive ensures asymmetric epigenetic inheritance R Ranjan, J Snedeker, X Chen BioRxiv, 416446, 2018 | 2 | 2018 |
Unidirectional fork movement coupled with strand-specific histone incorporation ensures asymmetric histone inheritance M Wooten, J Snedeker, Z Nizami, X Yang, R Ranjan, E Urban, JM Kim, ... bioRxiv, 242768, 2018 | 2 | 2018 |
A single N-terminal amino acid determines the distinct roles of histones H3 and H3.3 in the Drosophila male germline stem cell lineage C Chandrasekhara, R Ranjan, JA Urban, BEM Davis, WL Ku, J Snedeker, ... Plos Biology 21 (5), e3002098, 2023 | 1 | 2023 |
Combined inhibition of wee1 and poly (ADP ribose) polymerase1/2 synergistically inhibits acute myeloid leukemia cells by enhancing DNA damage and the induction of apoptosis JC Snedeker, TM Burleson, R Tibes, CC Porter Blood 124 (21), 3621, 2014 | 1 | 2014 |
Reduced Levels of Lagging Strand Polymerases Shape Stem Cell Chromatin J Snedeker, BEM Davis, R Ranjan, MI Wooten, J Blundon, X Chen bioRxiv, 2024.04. 26.591383, 2024 | | 2024 |
Roles of the distinct N-terminal amino acid between H3 and H3.3 in Drosophila male germline stem cell lineage C Chandrasekhara, R Ranjan, JA Urban, WL Ku, J Snedeker, K Zhao, ... bioRxiv, 2022.09. 03.506490, 2022 | | 2022 |
On the Mechanism and Function of Asymmetric Histone Inheritance J Snedeker Johns Hopkins University, 2022 | | 2022 |