| Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA C Zhang, D Samanta, H Lu, JW Bullen, H Zhang, I Chen, X He, ... Proceedings of the National Academy of Sciences 113 (14), E2047-E2056, 2016 | 967 | 2016 |
| Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells D Samanta, DM Gilkes, P Chaturvedi, L Xiang, GL Semenza Proceedings of the National Academy of Sciences 111 (50), E5429-E5438, 2014 | 503 | 2014 |
| HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells H Zhang, H Lu, L Xiang, JW Bullen, C Zhang, D Samanta, DM Gilkes, ... Proceedings of the National Academy of Sciences 112 (45), E6215-E6223, 2015 | 363 | 2015 |
| Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells D Samanta, Y Park, X Ni, H Li, CA Zahnow, E Gabrielson, F Pan, ... Proceedings of the National Academy of Sciences 115 (6), E1239-E1248, 2018 | 292 | 2018 |
| Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217-and ALKBH5-mediated modulation of RNA methylation in breast cancer cells C Zhang, WI Zhi, H Lu, D Samanta, I Chen, E Gabrielson, GL Semenza Oncotarget 7 (40), 64527, 2016 | 249 | 2016 |
| Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype H Lu, D Samanta, L Xiang, H Zhang, H Hu, I Chen, JW Bullen, ... Proceedings of the National Academy of Sciences 112 (33), E4600-E4609, 2015 | 246 | 2015 |
| PHGDH expression is required for mitochondrial redox homeostasis, breast cancer stem cell maintenance, and lung metastasis D Samanta, Y Park, SA Andrabi, LM Shelton, DM Gilkes, GL Semenza Cancer research 76 (15), 4430-4442, 2016 | 229 | 2016 |
| Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors D Samanta, GL Semenza Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1870 (1), 15-22, 2018 | 161 | 2018 |
| Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype L Xiang, DM Gilkes, H Hu, N Takano, W Luo, H Lu, JW Bullen, D Samanta, ... Oncotarget 5 (24), 12509, 2014 | 130 | 2014 |
| Alterations in the Smad pathway in human cancers D Samanta, PK Datta Frontiers in bioscience (Landmark edition) 17, 1281, 2012 | 124 | 2012 |
| Hypoxia Selectively Enhances Integrin α5β1 Receptor Expression in Breast Cancer to Promote Metastasis JA Ju, I Godet, IC Ye, J Byun, H Jayatilaka, SJ Lee, L Xiang, D Samanta, ... Molecular Cancer Research 15 (6), 723-734, 2017 | 119 | 2017 |
| Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment J Lan, H Lu, D Samanta, S Salman, Y Lu, GL Semenza Proceedings of the National Academy of Sciences 115 (41), E9640-E9648, 2018 | 117 | 2018 |
| Maintenance of redox homeostasis by hypoxia-inducible factors D Samanta, GL Semenza Redox biology 13, 331-335, 2017 | 111 | 2017 |
| Systems biology of oxygen homeostasis D Samanta, NR Prabhakar, GL Semenza Wiley Interdisciplinary Reviews: Systems Biology and Medicine 9 (4), e1382, 2017 | 95 | 2017 |
| Serine synthesis helps hypoxic cancer stem cells regulate redox D Samanta, GL Semenza Cancer research 76 (22), 6458-6462, 2016 | 65 | 2016 |
| Smoking attenuates transforming growth factor-β–mediated tumor suppression function through downregulation of Smad3 in lung cancer D Samanta, AL Gonzalez, N Nagathihalli, F Ye, DP Carbone, PK Datta Cancer Prevention Research 5 (3), 453-463, 2012 | 45 | 2012 |
| BIRC2 expression impairs anti-cancer immunity and immunotherapy efficacy D Samanta, TYT Huang, R Shah, Y Yang, F Pan, GL Semenza Cell reports 32 (8), 2020 | 32 | 2020 |
| Long-term smoking mediated down-regulation of Smad3 induces resistance to carboplatin in non-small cell lung cancer D Samanta, J Kaufman, DP Carbone, PK Datta Neoplasia 14 (7), 644-IN23, 2012 | 25 | 2012 |
| Role of TGF-β-induced Claudin-4 expression through c-Jun signaling in non-small cell lung cancer G Rachakonda, T Vu, L Jin, D Samanta, PK Datta Cellular signalling 28 (10), 1537-1544, 2016 | 22 | 2016 |
| In vitro assays of breast cancer stem cells D Samanta, GL Semenza Hypoxia: Methods and Protocols, 237-246, 2018 | 7 | 2018 |
John W. Bullen, Ph.D.Associate Director, AstraZenecaVerified email at astrazeneca.com
