Recent progress in the development of anti-malarial quinolones RM Beteck, FJ Smit, RK Haynes, DD N’Da Malaria journal 13, 1-10, 2014 | 94 | 2014 |
Antimalarial application of quinones: A recent update OPS Patel, RM Beteck, LJ Legoabe European Journal of Medicinal Chemistry 210, 113084, 2021 | 64 | 2021 |
Chemical classes presenting novel antituberculosis agents currently in different phases of drug development: A 2010–2020 review KT Angula, LJ Legoabe, RM Beteck Pharmaceuticals 14 (5), 461, 2021 | 40 | 2021 |
Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research OPS Patel, RM Beteck, LJ Legoabe European journal of medicinal chemistry 213, 113193, 2021 | 35 | 2021 |
Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites RM Beteck, R Seldon, D Coertzen, ME van der Watt, J Reader, ... COMMUNICATIONS CHEMISTRY- NATURE 1, 62, 2018 | 33 | 2018 |
Quinolone-isoniazid hybrids: Synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation RM Beteck, R Seldon, A Jordaan, DF Warner, HC Hoppe, D Laming, ... Medchemcomm 10 (2), 326-331, 2019 | 28 | 2019 |
Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective OPS Patel, OJ Jesumoroti, LJ Legoabe, RM Beteck European Journal of Medicinal Chemistry 210, 112994, 2021 | 24 | 2021 |
Quinolone: a versatile therapeutic compound class PS Dube, LJ Legoabe, RM Beteck Molecular Diversity 27 (3), 1501-1526, 2023 | 21 | 2023 |
Cinnamoyl-oxaborole amides: Synthesis and their in vitro biological activity M Gumbo, RM Beteck, T Mandizvo, R Seldon, DF Warner, HC Hoppe, ... Molecules 23 (8), 2038, 2018 | 20 | 2018 |
Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities RM Beteck, D Coertzen, FJ Smit, LM Birkholtz, RK Haynes, DD N’Da Bioorganic & Medicinal Chemistry Letters 26 (13), 3006-3009, 2016 | 20 | 2016 |
New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis RM Beteck, R Seldon, A Jordaan, DF Warner, HC Hoppe, D Laming, ... Molecules 24 (9), 1740, 2019 | 18 | 2019 |
Anti-trypanosomal and antimalarial properties of tetralone derivatives and structurally related benzocycloalkanones RM Beteck, LJ Legoabe, M Isaacs, SD Khanye, D Laming, HC Hoppe Medicina 55 (5), 206, 2019 | 14 | 2019 |
Easily accessed nitroquinolones exhibiting potent and selective anti-tubercular activity PS Dube, LJ Legoabe, A Jordaan, OJ Jesumoroti, T Tshiwawa, ... European journal of medicinal chemistry 213, 113207, 2021 | 13 | 2021 |
An update on development of small-molecule Plasmodial kinase inhibitors C Moolman, R Sluis, RM Beteck, LJ Legoabe Molecules 25 (21), 5182, 2020 | 12 | 2020 |
Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors MA Qhobosheane, LJ Legoabe, B Josselin, S Bach, S Ruchaud, ... Bioorganic & Medicinal Chemistry 28 (11), 115468, 2020 | 12 | 2020 |
Synthesis and biological evaluation of selected 7-azaindole derivatives as CDK9/Cyclin T and Haspin inhibitors L Pieterse, LJ Legoabe, RM Beteck, B Josselin, S Bach, S Ruchaud | 10 | 2020 |
Synthesis, in vitro cytotoxicity and trypanocidal evaluation of novel 1,3,6-substituted non-fluoroquinolones R.M. Beteck, M. Isaacs, H.C. Hoppe and S.D. Khanye South Africa Journal of Chemistry 71, 188-195, 2018 | 10* | 2018 |
Synthesis, antiplasmodial and antitrypanosomal evaluation of a series of novel 2-oxoquinoline-based thiosemicarbazone derivatives OT Darrell, ST Hulushe, TE Mtshare, RM Beteck, M Isaacs, D Laming, ... South African Journal of Chemistry 71, 174-181, 2018 | 9 | 2018 |
Assessment of the activity of decoquinate and its quinoline-O-carbamate derivatives against Toxoplasma gondii in vitro and in pregnant mice infected with T. gondii oocysts J Ramseier, D Imhof, N Anghel, K Hänggeli, RM Beteck, V Balmer, ... Molecules 26 (21), 6393, 2021 | 8 | 2021 |
Exploration of 7-azaindole-coumaranone hybrids and their analogues as protein kinase inhibitors MA Qhobosheane, RM Beteck, B Baratte, T Robert, S Ruchaud, S Bach, ... Chemico-Biological Interactions 343, 109478, 2021 | 8 | 2021 |