Structural basis for the aminoacid composition of proteins from halophilic archea X Tadeo, B López-Méndez, T Trigueros, A Laín, D Castaño, O Millet PLoS biology 7 (12), e1000257, 2009 | 177 | 2009 |
SARS-CoV-2 infection dysregulates the metabolomic and lipidomic profiles of serum C Bruzzone, M Bizkarguenaga, R Gil-Redondo, T Diercks, E Arana, ... Iscience 23 (10), 101645, 2020 | 154 | 2020 |
Diagnosis of invasive candidiasis by enzyme-linked immunosorbent assay using the N-terminal fragment of Candida albicans hyphal wall protein 1 A Laín, N Elguezabal, S Brena, JC García-Ruiz, A del Palacio, ... BMC microbiology 7 (1), 35, 2007 | 74 | 2007 |
Halophilic enzyme activation induced by salts G Ortega, A Laín, X Tadeo, B López-Méndez, D Castano, O Millet Scientific reports 1, 6, 2011 | 68 | 2011 |
Evaluation of a novel enzyme-linked immunosorbent assay to detect immunoglobulin G antibody to enolase for serodiagnosis of invasive candidiasis A Laín, MD Moragues, JCG Ruiz, J Mendoza, A Camacho, A del Palacio, ... Clinical and Vaccine Immunology 14 (3), 318-319, 2007 | 61 | 2007 |
Use of recombinant antigens for the diagnosis of invasive candidiasis A Laín, N Elguezabal, E Amutio, I Fernández de Larrinoa, MD Moragues, ... Clinical and Developmental Immunology 2008, 2008 | 59 | 2008 |
Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria P Urquiza, A Laín, A Sanz-Parra, J Moreno, G Bernardo-Seisdedos, ... Science translational medicine 10 (459), eaat7467, 2018 | 52 | 2018 |
Therapeutic potential of proteasome inhibitors in congenital erythropoietic porphyria JM Blouin, Y Duchartre, P Costet, M Lalanne, C Ged, A Lain, O Millet, ... Proceedings of the National Academy of Sciences, 201314177, 2013 | 41 | 2013 |
Uroporphyrinogen III synthase mutations related to congenital erythropoietic porphyria identify a key helix for protein stability A Fortian, D Castaño, G Ortega, A Laín, M Pons, O Millet Biochemistry 48 (2), 454-461, 2008 | 39 | 2008 |
Abnormal concentration of porphyrins in serum from COVID‐19 patients I San Juan, C Bruzzone, M Bizkarguenaga, G Bernardo‐Seisdedos, ... British journal of haematology 190 (5), e265, 2020 | 35 | 2020 |
Glycoprofile analysis of an intact glycoprotein as inferred by NMR spectroscopy L Unione, MP Lenza, A Ardá, P Urquiza, A Laín, JM Falcón-Pérez, ... ACS central science 5 (9), 1554-1561, 2019 | 35 | 2019 |
A molecular signature for the metabolic syndrome by urine metabolomics C Bruzzone, R Gil-Redondo, M Seco, R Barragán, L de la Cruz, C Cannet, ... Cardiovascular Diabetology 20 (1), 1-13, 2021 | 28 | 2021 |
Contribution of serum biomarkers to the diagnosis of invasive candidiasis A Laín, N Elguezabal, MD Moragues, JC García-Ruiz, A Del Palacio, ... Expert review of molecular diagnostics 8 (3), 315-325, 2008 | 26 | 2008 |
Tuning intracellular homeostasis of human uroporphyrinogen III synthase by enzyme engineering at a single hotspot of congenital erythropoietic porphyria F ben Bdira, E González, P Pluta, A Laín, A Sanz-Parra, JM Falcon-Perez, ... Human molecular genetics 23 (21), 5805-5813, 2014 | 24 | 2014 |
Structural, thermodynamic, and mechanistical studies in uroporphyrinogen III synthase: molecular basis of congenital erythropoietic porphyria A Fortian, D Castaño, E Gonzalez, A Laín, JM Falcon-Perez, O Millet Advances in protein chemistry and structural biology 83, 43-74, 2011 | 19 | 2011 |
Hereditary tyrosinemia type I–associated mutations in fumarylacetoacetate hydrolase reduce the enzyme stability and increase its aggregation rate I Macias, A Laín, G Bernardo-Seisdedos, D Gil, E Gonzalez, ... Journal of Biological Chemistry 294 (35), 13051-13060, 2019 | 16 | 2019 |
Serodiagnosis of mycoses using recombinant antigens N Elguezabal, F Lopitz-Otsoa, A Laín, IF de Larrinoa, MD Moragues, ... Mycopathologia 160 (2), 97-109, 2005 | 16 | 2005 |
Therapeutic targeting of fumaryl acetoacetate hydrolase in hereditary tyrosinemia type i J Gil-Martínez, I Macias, L Unione, G Bernardo-Seisdedos, F Lopitz-Otsoa, ... International journal of molecular sciences 22 (4), 1789, 2021 | 8 | 2021 |
New pharmacological therapies against congenital erythropoietic porphyria (CEP) PD Urquiza, A Lain, A Sanz, JM Falcon, O Millet PROTEIN SCIENCE 24, 64-64, 2015 | 2 | 2015 |
Evaluation of the Candida Enolasa ELISA IgG® test for the serodiagnosis of invasive candidiasis A Laín, MD Moragues, JCG Ruiz, J Mendoza, A Camacho, A del Palacio, ... Clinical and Vaccine Immunology, 2007 | 1 | 2007 |