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Joseph P O'Shea
Joseph P O'Shea
School of Pharmacy, University College Cork
Verified email at ucc.ie
Title
Cited by
Cited by
Year
Food for thought: formulating away the food effect–a PEARRL review
JP O'Shea, R Holm, CM O'Driscoll, BT Griffin
Journal of Pharmacy and Pharmacology 71 (4), 510-535, 2019
1012019
The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review
LJ Henze, NJ Koehl, JP O'Shea, ES Kostewicz, R Holm, BT Griffin
Journal of pharmacy and pharmacology 71 (4), 581-602, 2019
692019
Folate-targeted amphiphilic cyclodextrin. siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged …
JC Evans, M Malhotra, J Guo, JP O'Shea, K Hanrahan, A O'Neill, ...
Nanomedicine: Nanotechnology, Biology and Medicine 12 (8), 2341-2351, 2016
512016
In vitro dissolution models for the prediction of in vivo performance of an oral mesoporous silica formulation
CA McCarthy, W Faisal, JP O'Shea, C Murphy, RJ Ahern, KB Ryan, ...
Journal of Controlled Release 250, 86-95, 2017
412017
Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: in vitro, in vivo and in silico assessments
JP O’Shea, W Faisal, T Ruane-O’Hora, KJ Devine, ES Kostewicz, ...
European Journal of Pharmaceutics and Biopharmaceutics 96, 207-216, 2015
402015
Best practices in current models mimicking drug permeability in the gastrointestinal tract-An UNGAP review
JP O'Shea, P Augustijns, M Brandl, DJ Brayden, J Brouwers, BT Griffin, ...
European Journal of Pharmaceutical Sciences 170, 106098, 2022
382022
Machine learning methods for prediction of food effects on bioavailability: A comparison of support vector machines and artificial neural networks
H Bennett-Lenane, BT Griffin, JP O'Shea
European Journal of Pharmaceutical Sciences 168, 106018, 2022
272022
A retrospective biopharmaceutical analysis of> 800 approved oral drug products: are drug properties of solid dispersions and lipid-based formulations distinctive?
H Bennett-Lenane, JP O'Shea, CM O'Driscoll, BT Griffin
Journal of Pharmaceutical Sciences 109 (11), 3248-3261, 2020
232020
Toward the establishment of a standardized pre-clinical porcine model to predict food effects–Case studies on fenofibrate and paracetamol
LJ Henze, NJ Koehl, JP O'Shea, R Holm, M Vertzoni, BT Griffin
International journal of pharmaceutics: X 1, 100017, 2019
212019
Mesoporous silica-based dosage forms improve bioavailability of poorly soluble drugs in pigs: case example fenofibrate
JP O'Shea, K Nagarsekar, A Wieber, V Witt, E Herbert, CM O'Driscoll, ...
Journal of Pharmacy and Pharmacology 69 (10), 1284-1292, 2017
212017
Combining species specific in vitro & in silico models to predict in vivo food effect in a preclinical stage–case study of Venetoclax
LJ Henze, NJ Koehl, JP O'Shea, R Holm, M Vertzoni, BT Griffin
European Journal of Pharmaceutical Sciences 162, 105840, 2021
122021
Pre-clinical evaluation of a modified cyclodextrin-based nanoparticle for intestinal delivery of liraglutide
E Presas, S Tovar, J Cuñarro, JP O'Shea, CM O'Driscoll
Journal of Pharmaceutical Sciences 110 (1), 292-300, 2021
122021
Artificial neural networks to predict the apparent degree of supersaturation in supersaturated lipid-based formulations: a pilot study
H Bennett-Lenane, JP O’Shea, JD Murray, AR Ilie, R Holm, M Kuentz, ...
pharmaceutics 13 (9), 1398, 2021
82021
Applying computational predictions of biorelevant solubility ratio upon self-emulsifying lipid-based formulations dispersion to predict dose number
H Bennett-Lenane, NJ Koehl, PJ O'Dwyer, KJ Box, JP O'Shea, BT Griffin
Journal of Pharmaceutical Sciences 110 (1), 164-175, 2021
82021
Exploring porcine gastric and intestinal fluids using microscopic and solubility estimates: Impact of placebo self-emulsifying drug delivery system administration to inform bio …
H Bennett-Lenane, JR Jørgensen, NJ Koehl, LJ Henze, JP O'Shea, ...
European Journal of Pharmaceutical Sciences 161, 105778, 2021
52021
Mechanistic understanding of bioenabling formulation approaches to improve oral bioavailability using porcine in vivo and in silico models
JP O'Shea
University College Cork, 2018
12018
Exploring career choices of pharmacy graduates over 15 years: A cross-sectional evaluation
KL Fitzpatrick, EA Allen, BT Griffin, JP O'Shea, K Dalton, ...
Currents in Pharmacy Teaching and Learning, 2024
2024
The impact of drug-loading factors on the solid-state form of ritonavir-mesoporous silica systems
T Al-Dagamin, J O'Shea, A Crean
British Journal of Pharmacy 7 (2), S1-S2, 2022
2022
Lipid‐based Formulations
JP O'Shea, CM O'Driscoll, BT Griffin
Oral Drug Delivery for Modified Release Formulations, 137-160, 2022
2022
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