TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding JA Schofield, EE Duffy, L Kiefer, MC Sullivan, MD Simon Nature methods 15 (3), 221-225, 2018 | 214 | 2018 |
Expanding the nucleoside recoding toolkit: revealing RNA population dynamics with 6-thioguanosine L Kiefer, JA Schofield, MD Simon Journal of the American Chemical Society 140 (44), 14567-14570, 2018 | 35 | 2018 |
Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... Molecular cell 82 (6), 1107-1122. e7, 2022 | 27 | 2022 |
RhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport … MA Wallert, D Hammes, T Nguyen, L Kiefer, N Berthelsen, A Kern, ... Cellular Signalling 27 (3), 498-509, 2015 | 26 | 2015 |
WAPL functions as a rheostat of Protocadherin isoform diversity that controls neural wiring L Kiefer, A Chiosso, J Langen, A Buckley, S Gaudin, SM Rajkumar, ... Science 380 (6651), eadf8440, 2023 | 9 | 2023 |
Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin M Machyna, L Kiefer, MD Simon Nature Structural & Molecular Biology 27 (3), 297-304, 2020 | 9 | 2020 |
Multi-omics profiling of U2AF1 mutants dissects pathogenic mechanisms affecting RNA granules in myeloid malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... bioRxiv, 2021.04. 22.441020, 2021 | 3 | 2021 |
Internally controlled RNA sequencing comparisons using nucleoside recoding chemistry MCS Courvan, RO Niederer, IW Vock, L Kiefer, WV Gilbert, MD Simon Nucleic Acids Research 50 (19), e110-e110, 2022 | 2 | 2022 |
Cohesin erases genomic-proximity biases to drive stochastic Protocadherin expression for proper neural wiring L Kiefer, GIF Servito, SM Rajkumar, J Langen, A Chiosso, A Buckley, ... bioRxiv, 2022.03. 09.483674, 2022 | 2 | 2022 |
Improving the study of RNA dynamics through advances in RNA-seq with metabolic labeling and nucleotide-recoding chemistry JT Zimmer, IW Vock, JA Schofield, L Kiefer, MH Moon, MD Simon bioRxiv, 2023 | 1 | 2023 |
Investigation of the interaction and role of CHP1 and CHP2 with NHE1 in lung fibroblasts L Kiefer, M Wallert, J Provost The FASEB Journal 29, 725.17, 2015 | 1 | 2015 |
Cohesin erases genomic-proximity biases to drive stochastic Protocadherin expression for proper neural wiring D Canzio, L Kiefer, GI Servito, S Rajkumar, J Langen, A Chiosso, ... | | 2022 |
U2AF1 Mutations Enhance Stress Granule Response in Myeloid Malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... Blood 138 (Supplement 1), 321-321, 2021 | | 2021 |
Author Correction: Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin M Machyna, L Kiefer, MD Simon Nature Structural & Molecular Biology 27 (4), 400-400, 2020 | | 2020 |
Investigating RNA Population Dynamics through Nucleotide Recoding: Extending the TimeLapse-Seq Toolkit to 6-Thioguanosine L Kiefer Yale University, 2020 | | 2020 |
Stella’s Role in Oocyte DNA Methylation Suggests Additional Activities of DNMT1 L Kiefer, MD Simon Biochemistry 58 (14), 1833-1834, 2019 | | 2019 |
Protocol for TimeLapse-seq M Simon, M Sullivan, J Schofield, E Duffy, L Kiefer | | 2018 |
Studying Stimulus‐Induced Changes in RNA Dynamics by Mutational Mapping through TimeLapse‐seq L Kiefer, JA Schofield, MD Simon The FASEB Journal 32, lb23-lb23, 2018 | | 2018 |