| Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ... Cell 162 (6), 1217-1228, 2015 | 1239 | 2015 |
| A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade DS Thommen, VH Koelzer, P Herzig, A Roller, M Trefny, S Dimeloe, ... Nature medicine 24 (7), 994-1004, 2018 | 884 | 2018 |
| α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming PS Liu, H Wang, X Li, T Chao, T Teav, S Christen, G Di Conza, WC Cheng, ... Nature immunology 18 (9), 985-994, 2017 | 712 | 2017 |
| Regulatory circuits of T cell function in cancer DE Speiser, PC Ho, G Verdeil Nature Reviews Immunology 16 (10), 599-611, 2016 | 529 | 2016 |
| Navigating metabolic pathways to enhance antitumour immunity and immunotherapy X Li, M Wenes, P Romero, SCC Huang, SM Fendt, PC Ho Nature reviews Clinical oncology 16 (7), 425-441, 2019 | 504 | 2019 |
| CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors H Wang, F Franco, YC Tsui, X Xie, MP Trefny, R Zappasodi, SR Mohmood, ... Nature immunology 21 (3), 298-308, 2020 | 393 | 2020 |
| Lactate modulation of immune responses in inflammatory versus tumour microenvironments M Certo, CH Tsai, V Pucino, PC Ho, C Mauro Nature Reviews Immunology 21 (3), 151-161, 2021 | 389 | 2021 |
| IL-7-induced glycerol transport and TAG synthesis promotes memory CD8+ T cell longevity G Cui, MM Staron, SM Gray, PC Ho, RA Amezquita, J Wu, SM Kaech Cell 161 (4), 750-761, 2015 | 337 | 2015 |
| Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion YR Yu, H Imrichova, H Wang, T Chao, Z Xiao, M Gao, M Rincon-Restrepo, ... Nature immunology 21 (12), 1540-1551, 2020 | 310 | 2020 |
| The interleukin-2-mTORc1 kinase axis defines the signaling, differentiation, and metabolism of T helper 1 and follicular B helper T cells JP Ray, MM Staron, JA Shyer, PC Ho, HD Marshall, SM Gray, BJ Laidlaw, ... Immunity 43 (4), 690-702, 2015 | 302 | 2015 |
| Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors S Xu, O Chaudhary, P Rodríguez-Morales, X Sun, D Chen, R Zappasodi, ... Immunity 54 (7), 1561-1577. e7, 2021 | 297 | 2021 |
| CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours R Zappasodi, I Serganova, IJ Cohen, M Maeda, M Shindo, ... Nature 591 (7851), 652-658, 2021 | 230 | 2021 |
| Immunity, hypoxia, and metabolism–the Ménage à Trois of cancer: implications for immunotherapy C Riera-Domingo, A Audigé, S Granja, WC Cheng, PC Ho, F Baltazar, ... Physiological reviews 100 (1), 1-102, 2020 | 217 | 2020 |
| Metabolic and epigenetic regulation of T-cell exhaustion F Franco, A Jaccard, P Romero, YR Yu, PC Ho Nature metabolism 2 (10), 1001-1012, 2020 | 201 | 2020 |
| Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity Y Guo, YQ Xie, M Gao, Y Zhao, F Franco, M Wenes, I Siddiqui, ... Nature immunology 22 (6), 746-756, 2021 | 184 | 2021 |
| The NAD-booster nicotinamide riboside potently stimulates hematopoiesis through increased mitochondrial clearance N Vannini, V Campos, M Girotra, V Trachsel, S Rojas-Sutterlin, J Tratwal, ... Cell stem cell 24 (3), 405-418. e7, 2019 | 175 | 2019 |
| Metabolic regulation of Tregs in cancer: opportunities for immunotherapy H Wang, F Franco, PC Ho Trends in cancer 3 (8), 583-592, 2017 | 171 | 2017 |
| Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells B Mastelic-Gavillet, B Navarro Rodrigo, L Décombaz, H Wang, ... Journal for immunotherapy of cancer 7, 1-16, 2019 | 157 | 2019 |
| ER stress responses: an emerging modulator for innate immunity G Di Conza, PC Ho Cells 9 (3), 695, 2020 | 156 | 2020 |
| Macrophage-derived glutamine boosts satellite cells and muscle regeneration M Shang, F Cappellesso, R Amorim, J Serneels, F Virga, G Eelen, ... Nature 587 (7835), 626-631, 2020 | 137 | 2020 |
