SUMO chain-induced dimerization activates RNF4 A Rojas-Fernandez, A Plechanovova, N Hattersley, E Jaffray, MH Tatham, ... Molecular cell 53 (6), 880-892, 2014 | 95 | 2014 |
An affinity-directed protein missile system for targeted proteolysis LJ Fulcher, T Macartney, P Bozatzi, A Hornberger, A Rojas-Fernandez, ... Open biology 6 (10), 160255, 2016 | 85 | 2016 |
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ... Molecular psychiatry 28 (7), 2878-2893, 2023 | 76 | 2023 |
Iron supply determines apical/basolateral membrane distribution of intestinal iron transporters DMT1 and ferroportin 1 MT Núñez, V Tapia, A Rojas, P Aguirre, F Gómez, F Nualart American Journal of Physiology-Cell Physiology 298 (3), C477-C485, 2010 | 54 | 2010 |
Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody G Valenzuela Nieto, R Jara, D Watterson, N Modhiran, AA Amarilla, ... Scientific reports 11 (1), 3318, 2021 | 50 | 2021 |
Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9 A Rojas-Fernandez, L Herhaus, T Macartney, C Lachaud, RT Hay, ... Scientific Reports 5 (1), 9811, 2015 | 50 | 2015 |
The potential role of SARS-COV-2 in the pathogenesis of Parkinson's disease P Chana-Cuevas, P Salles-Gandara, A Rojas-Fernandez, ... Frontiers in neurology 11, 1044, 2020 | 42 | 2020 |
Autophagosomes cooperate in the degradation of intracellular C-terminal fragments of the amyloid precursor protein via the MVB/lysosomal pathway AE González, VC Muñoz, VA Cavieres, HA Bustamante, VH Cornejo, ... FASEB, 2017 | 42 | 2017 |
Turning the RING domain protein MdmX into an active ubiquitin-protein ligase S Iyappan, HP Wollscheid, A Rojas-Fernandez, A Marquardt, HC Tang, ... Journal of biological chemistry 285 (43), 33065-33072, 2010 | 37 | 2010 |
DHX15 regulates CMTR1-dependent gene expression and cell proliferation F Inesta-Vaquera, VK Chaugule, A Galloway, L Chandler, ... Life science alliance 1 (3), 2018 | 36 | 2018 |
Regulation of membrane ruffling by polarized STIM1 and ORAI1 in cortactin-rich domains AM Lopez-Guerrero, P Tomas-Martin, C Pascual-Caro, T Macartney, ... Scientific reports 7 (1), 383, 2017 | 26 | 2017 |
Apical distribution of HFE–β2-microglobulin is associated with inhibition of apical iron uptake in intestinal epithelia cells M Arredondo, V Tapia, A Rojas, P Aguirre, F Reyes, MP Marzolo, ... Biometals 19, 379-388, 2006 | 26 | 2006 |
Hereditary hemochromatosis: an opportunity for gene therapy F Ezquer, MT Núñez, A Rojas, J Asenjo, Y Israel Biological research 39 (1), 113-124, 2006 | 18 | 2006 |
The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling Golgi-to-ER retrograde transport HA Bustamante, K Cereceda, AE González, GE Valenzuela, ... Cells 9 (3), 777, 2020 | 14 | 2020 |
Antioxidant responses of cortex neurons to iron loading P Aguirre, N Mena, V Tapia, A Rojas, M Arredondo, MT NuÑez Biological Research 39 (1), 103-104, 2006 | 13 | 2006 |
Nanobodies: cOVID-19 and future perspectives G Valenzuela-Nieto, Z Miranda-Chacon, C Salinas-Rebolledo, R Jara, ... Frontiers in Drug Discovery 2, 927164, 2022 | 9 | 2022 |
Fast isolation of sub-nanomolar affinity alpaca nanobody against the Spike RBD of SARS-CoV-2 by combining bacterial display and a simple single-step density gradient selection GEV Nieto, R Jara, D Watterson, N Modhiran, AA Amarilla, J Himelreichs, ... | 8 | 2020 |
Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology J Aguado, AA Amarilla, A Taherian Fard, EA Albornoz, A Tyshkovskiy, ... Nature Aging 3 (12), 1561-1575, 2023 | 7 | 2023 |
Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG S Espinoza, SB Arredondo, F Barake, F Carvajal, FG Guerrero, ... BMC biology 18, 1-17, 2020 | 7 | 2020 |
WDR90 is a new component of the NLRC4 inflammasome involved in Salmonella Typhimurium resistance A Valera-Pérez, SD Tyrkalska, C Viana, A Rojas-Fernández, P Pelegrín, ... Developmental & Comparative Immunology 100, 103428, 2019 | 7 | 2019 |