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L. A. Liggett
L. A. Liggett
Other namesAlex Liggett, Alexander Liggett
Postdoctoral Fellow at Harvard Medical School, The Broad Institute, and Boston Children's
Verified email at broadinstitute.org - Homepage
Title
Cited by
Cited by
Year
Trisomy 21 consistently activates the interferon response
KD Sullivan, HC Lewis, AA Hill, A Pandey, LP Jackson, JM Cabral, ...
Elife 5, e16220, 2016
2562016
Unraveling hematopoiesis through the lens of genomics
LA Liggett, VG Sankaran
Cell 182 (6), 1384-1400, 2020
1202020
The burden of trisomy 21 disrupts the proteostasis network in Down syndrome
S Aivazidis, CM Coughlan, AK Rauniyar, H Jiang, LA Liggett, KN Maclean, ...
Plos one 12 (4), e0176307, 2017
632017
Changing mutational and adaptive landscapes and the genesis of cancer
LA Liggett, J DeGregori
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1867 (2), 84-94, 2017
462017
Variant to function mapping at single-cell resolution through network propagation
F Yu, LD Cato, C Weng, LA Liggett, S Jeon, K Xu, CWK Chiang, ...
Nature Biotechnology 40 (11), 1644-1653, 2022
302022
Clonal hematopoiesis in sickle cell disease
LA Liggett, LD Cato, JS Weinstock, Y Zhang, SM Nouraie, MT Gladwin, ...
The Journal of Clinical Investigation 132 (4), 2022
292022
Precocious clonal hematopoiesis in Down syndrome is accompanied by immune dysregulation
LA Liggett, MD Galbraith, KP Smith, KD Sullivan, RE Granrath, ...
Blood Advances 5 (7), 1791-1796, 2021
142021
FERMI: a novel method for sensitive detection of rare mutations in somatic tissue
LA Liggett, A Sharma, S De, J DeGregori
G3: Genes, Genomes, Genetics 9 (9), 2977-2987, 2019
102019
Trisomy 21 consistently activates the interferon response. Elife 5
KD Sullivan, HC Lewis, AA Hill, A Pandey, LP Jackson, JM Cabral, ...
eLife Sciences Publications Limited 5, 1709, 2016
82016
Deciphering cell states and genealogies of human hematopoiesis
C Weng, F Yu, D Yang, M Poeschla, LA Liggett, MG Jones, X Qiu, ...
Springer Science and Business Media LLC, 2024
72024
Optical imaging of targeted β-galactosidase in brain tumors to detect EGFR levels
AM Broome, G Ramamurthy, K Lavik, A Liggett, I Kinstlinger, J Basilion
Bioconjugate chemistry 26 (4), 660-668, 2015
62015
Measuring gender differences in attitudes using the lost-letter technique
L Liggett, C Blair, S Kennison
Journal of Scientific Psychology, 16-24, 2010
42010
Sowing the Seeds of Clonal Hematopoiesis
LA Liggett, RA Voit, VG Sankaran
Cell Stem Cell 27 (2), 195-197, 2020
22020
Conserved patterns of somatic mutations in human peripheral blood cells
LA Liggett, A Sharma, S De, J DeGregori
bioRxiv, 208066, 2017
22017
Patchwork cancer predisposition
LA Liggett, VG Sankaran
Cancer discovery 12 (4), 889-891, 2022
12022
A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution
AI Rozhok, RE Silberman, KC Higa, LA Liggett, A Amon, J DeGregori
Scientific Reports 10 (1), 12198, 2020
2020
Identifying Rare Somatic Mutations as a Means of Understanding Tissue Clonal Evolution
LA Liggett
University of Colorado Denver, Anschutz Medical Campus, 2019
2019
Tumor imaging via β-galactosidase fragment complementation with a multifunctional targeted-reporter complex
AM Broome, K Lavik, G Ramamurthy, LA Liggett, RS Agnes, JP Basilion
Cancer Research 70 (8_Supplement), 4341-4341, 2010
2010
Effects of unloading (HS) and loading (exercise training) on overall work capacity in rats.
F Silva, I Bederman, A Liggett, M Cabrera
The FASEB Journal 22, 121-121, 2008
2008
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Articles 1–19