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Jyothi Mahadevan
Jyothi Mahadevan
Senior Research Scientist, OnKure Therapeutics, Boulder CO
Verified email at onkure.com
Title
Cited by
Cited by
Year
Poly (ADP-ribose) polymerase 1 searches DNA via a ‘monkey bar’mechanism
J Rudolph, J Mahadevan, P Dyer, K Luger
Elife 7, e37818, 2018
722018
The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer
J Rudolph, UM Muthurajan, M Palacio, J Mahadevan, G Roberts, ...
Molecular cell 81 (24), 4994-5006. e5, 2021
502021
Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1
G Gaullier, G Roberts, UM Muthurajan, S Bowerman, J Rudolph, ...
PLoS One 15 (11), e0240932, 2020
392020
Efficient differentiation of murine embryonic stem cells requires the binding of CXXC finger protein 1 to DNA or methylated histone H3-Lys4
J Mahadevan, DG Skalnik
Gene 594 (1), 1-9, 2016
222016
Probing the conformational changes associated with DNA binding to PARP1
J Rudolph, J Mahadevan, K Luger
Biochemistry 59 (21), 2003-2011, 2020
192020
Q-FADD: a mechanistic approach for modeling the accumulation of proteins at sites of DNA damage
J Mahadevan, J Rudolph, A Jha, JW Tay, J Dragavon, EM Grumstrup, ...
Biophysical Journal 116 (11), 2224-2233, 2019
152019
Quantitating repair protein accumulation at DNA lesions: Past, present, and future
J Mahadevan, S Bowerman, K Luger
DNA repair 81, 102650, 2019
112019
Dynamics of endogenous PARP1 and PARP2 during DNA damage revealed by live-cell single-molecule imaging
J Mahadevan, A Jha, J Rudolph, S Bowerman, D Narducci, AS Hansen, ...
IScience 26 (1), 2023
92023
Automated modeling of protein accumulation at DNA damage sites using qFADD. py
S Bowerman, J Mahadevan, P Benson, J Rudolph, K Luger
Biological imaging 2, e8, 2022
42022
Q-FADD: a mechanistic approach for modeling the accumulation of proteins at sites of DNA damage by free diffusion
J Mahadevan, J Rudolph, A Jha, JW Tay, J Dragavon, EM Grumstrup, ...
bioRxiv, 373043, 2018
12018
The role of CFP1 in murine embryonic stem cell function and liver regeneration
J Mahadevan
Indiana University-Purdue University Indianapolis, 2015
12015
OKI-1546 is a selective, orally bioavailable inhibitor of CDK12 that causes tumor regression in multiple preclinical cancer models
AA Strait, DA Mareska, J Mahadevan, CA Schulte, Y Izrayelit, ML Boys, ...
Cancer Research 83 (7_Supplement), 1635-1635, 2023
2023
Extracting Protein Recruitment Kinetics to DNA Damage using qFADD. py
S Bowerman, J Mahadevan, P Benson, J Rudolph, K Luger
Biophysical Journal 120 (3), 82a-83a, 2021
2021
Monkey Business: How to Move in the DNA Jungle.
K Luger, J Rudolph, J Mahadevan, A Jha, S Bowerman, E Grumstrup
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 60, 31-32, 2019
2019
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