| ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site SM Le Gall, T Maretzky, PDA Issuree, XD Niu, K Reiss, P Saftig, R Khokha, ... Journal of cell science 123 (22), 3913-3922, 2010 | 256 | 2010 |
| iRHOM2 is a critical pathogenic mediator of inflammatory arthritis PDA Issuree, T Maretzky, DR McIlwain, S Monette, X Qing, PA Lang, ... The Journal of clinical investigation 123 (2), 928-932, 2013 | 193 | 2013 |
| iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding T Maretzky, DR McIlwain, PDA Issuree, X Li, J Malapeira, S Amin, ... Proceedings of the National Academy of Sciences 110 (28), 11433-11438, 2013 | 180 | 2013 |
| iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling X Li, T Maretzky, G Weskamp, S Monette, X Qing, PDA Issuree, ... Proceedings of the National Academy of Sciences 112 (19), 6080-6085, 2015 | 157 | 2015 |
| iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling X Qing, Y Chinenov, P Redecha, M Madaio, JJTH Roelofs, G Farber, ... The Journal of clinical investigation 128 (4), 1397-1412, 2018 | 86 | 2018 |
| Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages ML Sellars, JR Huh, K Day, PD Issuree, C Galan, S Gobeil, D Absher, ... Nature immunology 16 (7), 746-754, 2015 | 81 | 2015 |
| Resveratrol attenuates C5a‐induced inflammatory responses in vitro and in vivo by inhibiting phospholipase D and sphingosine kinase activities PDA Issuree, PN Pushparaj, S Pervaiz, AJ Melendez The FASEB journal 23 (8), 2412-2424, 2009 | 72 | 2009 |
| Heritable gene regulation in the CD4: CD8 T cell lineage choice PDA Issuree, CP Ng, DR Littman Frontiers in immunology 8, 250073, 2017 | 39 | 2017 |
| Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development PD Issuree, K Day, C Au, R Raviram, P Zappile, JA Skok, HH Xue, ... Nature communications 9 (1), 3594, 2018 | 34 | 2018 |
| Loss of RHBDF2 results in an early-onset spontaneous murine colitis R Geesala, W Schanz, M Biggs, G Dixit, J Skurski, P Gurung, ... Journal of leukocyte biology 105 (4), 767-781, 2019 | 32 | 2019 |
| Novel functions of inactive rhomboid proteins in immunity and disease R Geesala, PD Issuree, T Maretzky Journal of leukocyte biology 106 (4), 823-835, 2019 | 22 | 2019 |
| Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation J Skurski, CM Penniman, R Geesala, G Dixit, P Pulipati, G Bhardwaj, ... Metabolism 106, 154194, 2020 | 20 | 2020 |
| A pathophysiological perspective on COVID-19's lethal complication: from viremia to hypersensitivity pneumonitis-like immune dysregulation MA Sanchez-Gonzalez, D Moskowitz, PD Issuree, G Yatzkan, SAA Rizvi, ... Infection & chemotherapy 52 (3), 335, 2020 | 19 | 2020 |
| iRhom2 regulates CSF1R cell surface expression and non‐steady state myelopoiesis in mice X Qing, L D. Rogers, A Mortha, Y Lavin, P Redecha, PD Issuree, ... European journal of immunology 46 (12), 2737-2748, 2016 | 19 | 2016 |
| The role of iRhom2 in metabolic and cardiovascular-related disorders R Geesala, PD Issuree, T Maretzky Frontiers in cardiovascular medicine 7, 612808, 2020 | 8 | 2020 |
| The threshold effect: lipopolysaccharide-induced inflammatory responses in primary macrophages are differentially regulated in an iRhom2-dependent manner J Skurski, G Dixit, CP Blobel, PD Issuree, T Maretzky Frontiers in cellular and infection microbiology 10, 620392, 2021 | 5 | 2021 |
| CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element A Teghanemt, P Pulipati, K Misel-Wuchter, K Day, MS Yorek, R Yi, ... Nature communications 13 (1), 1477, 2022 | 4 | 2022 |
| Differences in H3K4me3 and chromatin accessibility contribute to altered T‐cell receptor signaling in neonatal naïve CD4 T cells JR Bermick, P Issuree, A denDekker, KA Gallagher, D Santillan, S Kunkel, ... Immunology and cell biology 100 (7), 562-579, 2022 | 3 | 2022 |
| Neuronal IL-17 controls C. elegans developmental diapause through CEP-1/p53 A Godthi, S Min, S Das, J Cruz-Corchado, A Deonarine, K Misel-Wuchter, ... BioRxiv, 2022.11. 22.517560, 2022 | 2 | 2022 |
| DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation A Teghanemt, K Misel‐Wuchter, J Heath, A Thurman, P Pulipati, G Dixit, ... EMBO reports 24 (5), e55543, 2023 | 1 | 2023 |
