A nontoxic pain killer designed by modeling of pathological receptor conformations V Spahn, G Del Vecchio, D Labuz, A Rodriguez-Gaztelumendi, N Massaly, ... Science 355 (6328), 966-969, 2017 | 213 | 2017 |
Pain-induced negative affect is mediated via recruitment of the nucleus accumbens kappa opioid system N Massaly, BA Copits, AR Wilson-Poe, L Hipólito, T Markovic, HJ Yoon, ... Neuron 102 (3), 564-573. e6, 2019 | 163 | 2019 |
Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice T Duparc, A Colom, PD Cani, N Massaly, S Rastrelli, A Drougard, ... Antioxidants & redox signaling 15 (6), 1477-1496, 2011 | 104 | 2011 |
Pain induces adaptations in ventral tegmental area dopamine neurons to drive anhedonia-like behavior T Markovic, CE Pedersen, N Massaly, YM Vachez, B Ruyle, CA Murphy, ... Nature neuroscience 24 (11), 1601-1613, 2021 | 69 | 2021 |
A trigger for opioid misuse: chronic pain and stress dysregulate the mesolimbic pathway and kappa opioid system N Massaly, JA Morón, R Al-Hasani Frontiers in neuroscience 10, 215259, 2016 | 63 | 2016 |
Jejunum inflammation in obese and diabetic mice impairs enteric glucose detection and modifies nitric oxide release in the hypothalamus T Duparc, D Naslain, A Colom, GG Muccioli, N Massaly, NM Delzenne, ... Antioxidants & redox signaling 14 (3), 415-423, 2011 | 46 | 2011 |
Roles of the ubiquitin proteasome system in the effects of drugs of abuse N Massaly, B Francès, L Moulédous Frontiers in molecular neuroscience 7, 99, 2015 | 36 | 2015 |
Morphine-associated contextual cues induce structural plasticity in hippocampal CA1 pyramidal neurons AK Fakira, N Massaly, O Cohensedgh, A Berman, JA Morón Neuropsychopharmacology 41 (11), 2668-2678, 2016 | 32 | 2016 |
Involvement of protein degradation by the ubiquitin proteasome system in opiate addictive behaviors N Massaly, L Dahan, M Baudonnat, C Hovnanian, K Rekik, M Solinas, ... Neuropsychopharmacology 38 (4), 596-604, 2013 | 32 | 2013 |
Synthesis and pharmacology of a novel μ–δ opioid receptor heteromer-selective agonist based on the carfentanyl template A Faouzi, R Uprety, I Gomes, N Massaly, AI Keresztes, V Le Rouzic, ... Journal of medicinal chemistry 63 (22), 13618-13637, 2020 | 24 | 2020 |
Endogenous opioid systems alterations in pain and opioid use disorder JA Higginbotham, T Markovic, N Massaly, JA Morón Frontiers in systems neuroscience 16, 1014768, 2022 | 22 | 2022 |
Modulation of μ‐opioid receptor activation by acidic pH is dependent on ligand structure and an ionizable amino acid residue J Meyer, G Del Vecchio, V Seitz, N Massaly, C Stein British Journal of Pharmacology 176 (23), 4510-4520, 2019 | 17 | 2019 |
Behavioral outcomes of complete Freund adjuvant–induced inflammatory pain in the rodent hind paw: a systematic review and meta-analysis DJ Burek, N Massaly, HJ Yoon, M Doering, JA Morón Pain 163 (5), 809-819, 2022 | 16 | 2022 |
Pain and opioid systems, implications in the opioid epidemic N Massaly, JA Morón Current opinion in behavioral sciences 26, 69-74, 2019 | 13 | 2019 |
Mu-opioid receptor and receptor tyrosine kinase crosstalk: Implications in mechanisms of opioid tolerance, reduced analgesia to neuropathic pain, dependence, and reward MC Gamble, BR Williams, N Singh, L Posa, Z Freyberg, RW Logan, ... Frontiers in Systems Neuroscience 16, 1059089, 2022 | 12 | 2022 |
Uncovering the analgesic effects of a pH-dependent mu-opioid receptor agonist using a model of nonevoked ongoing pain N Massaly, J Temp, H Machelska, C Stein Pain 161 (12), 2798-2804, 2020 | 11 | 2020 |
Pain, negative affective states and opioid-based analgesics: Safer pain therapies to dampen addiction N Massaly, T Markovic, M Creed, R Al-Hasani, CM Cahill, JA Moron International Review of Neurobiology 157, 31-68, 2021 | 7 | 2021 |
4th, McCall JG, Al-Hasani R, Bruchas MR, Morón JA (2019) Pain-induced negative affect is mediated via recruitment of the nucleus accumbens kappa opioid system N Massaly, BA Copits, AR Wilson-Poe, L Hipólito, T Markovic, HJ Yoon, ... Neuron 102 (3), 564-573, 0 | 7 | |
Long-term inflammatory pain does not impact exploratory behavior and stress coping strategies in mice DJ Burek, N Massaly, M Doering, A Zec, J Gaelen, JA Morón Pain 162 (6), 1705-1721, 2021 | 6 | 2021 |
(323) Kappa opioid receptors in the nucleus accumbens mediate pain-induced decrease in motivated behavior N Massaly, A Ream, L Hipolito, A Wilson-Poe, B Walker, M Bruchas, ... The Journal of Pain 17 (4), S56, 2016 | 4 | 2016 |