The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1 L Barnard, N Nikolaou, C Louw, L Schiffer, H Gibson, LC Gilligan, ... The Journal of steroid biochemistry and molecular biology 202, 105724, 2020 | 19 | 2020 |
Quantifying community-wide antibiotic usage via urban water fingerprinting: Focus on contrasting resource settings in South Africa E Holton, C Louw, E Archer, T Louw, G Wolfaardt, B Kasprzyk-Hordern Water Research 240, 120110, 2023 | 3 | 2023 |
Supervised machine learning with feature selection for prioritization of targets related to time-based cellular dysfunction in aging N Truter, ZJ van Rensburg, R Oudrhiri, R Singh, C Louw bioRxiv, 2022.06. 24.497511, 2022 | 2 | 2022 |
Computational modelling of the Δ4 and Δ5 adrenal steroidogenic pathways provides insight into hypocortisolism C Louw, EJ van Schalkwyk, R Conradie, R Louw, Y Engelbrecht, ... Molecular and cellular endocrinology 526, 111194, 2021 | 1 | 2021 |
Computational modelling of steroid hormone biosynthesis and metabolism C Louw Stellenbosch: Stellenbosch University, 2020 | 1 | 2020 |
ALaSCA: A novel in silico simulation platform to untangle biological pathway mechanisms, with a case study in Type 1 Diabetes progression C Louw, N Truter, W Bergh, M van den Heever, S Horn, R Oudrhiri, ... bioRxiv, 2023.03. 16.532913, 2023 | | 2023 |
ALaSCA: a computational platform for quantifying the effect of proteins using Pearlian causal inference, with an example application in Alzheimer’s disease N Truter, Z Jansen van Rensburg, R Oudrhiri, DD Van Niekerk, B Loos, ... bioRxiv, 2022.10. 31.514546, 2022 | | 2022 |
Dynamic mathematical model development and validation of in vitro Mycobacterium smegmatis growth under nutrient-and pH-stress D Apiyo, JM Mouton, C Louw, SL Sampson, TM Louw Journal of Theoretical Biology 532, 110921, 2022 | | 2022 |
Comparison of progress curve analysis and initial rate kinetics for the estimation of identifiable enzyme kinetic parameters: a case study using two glycolytic enzymes from … C Louw Stellenbosch: Stellenbosch University, 2016 | | 2016 |