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Jeffrey D Steimle
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TBX5: a key regulator of heart development
JD Steimle, IP Moskowitz
Current topics in developmental biology 122, 195-221, 2017
1512017
De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects
JR Priest, K Osoegawa, N Mohammed, V Nanda, R Kundu, K Schultz, ...
PLoS genetics 12 (4), e1005963, 2016
1052016
The cardiac TBX5 interactome reveals a chromatin remodeling network essential for cardiac septation
L Waldron, JD Steimle, TM Greco, NC Gomez, KM Dorr, J Kweon, ...
Developmental cell 36 (3), 262-275, 2016
882016
Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation
AD Hoffmann, XH Yang, O Burnicka-Turek, JD Bosman, X Ren, ...
PLoS genetics 10 (10), e1004604, 2014
882014
Evolutionarily conserved Tbx5Wnt2/2b pathway orchestrates cardiopulmonary development
JD Steimle, SA Rankin, CE Slagle, J Bekeny, AB Rydeen, SSK Chan, ...
Proceedings of the National Academy of Sciences 115 (45), E10615-E10624, 2018
562018
Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms
O Burnicka-Turek, JD Steimle, W Huang, L Felker, A Kamp, J Kweon, ...
Human molecular genetics 25 (14), 3011-3028, 2016
552016
Transcriptional patterning of the ventricular cardiac conduction system
O Burnicka-Turek, MT Broman, JD Steimle, BJ Boukens, NB Petrenko, ...
Circulation research 127 (3), e94-e106, 2020
202020
Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development
SA Rankin, JD Steimle, XH Yang, AB Rydeen, K Agarwal, P Chaturvedi, ...
Elife 10, e69288, 2021
192021
The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model
RC Polk, P Gergics, JD Steimle, H Li, IP Moskowitz, SA Camper, ...
BMC Developmental Biology 15, 1-12, 2015
192015
Transcriptional dysregulation underlies both monogenic arrhythmia syndrome and common modifiers of cardiac repolarization
KR Bersell, T Yang, JD Mosley, AM Glazer, AT Hale, DO Kryshtal, K Kim, ...
Circulation 147 (10), 824-840, 2023
102023
Hedgehog signaling controls progenitor differentiation timing during heart development
M Rowton, AD Hoffmann, JD Steimle, XH Yang, A Guzzetta, S Lazarevic, ...
bioRxiv, 2018
7*2018
Decoding the PITX2-controlled genetic network in atrial fibrillation
JD Steimle, FJG Canozo, M Park, ZA Kadow, MAH Samee, JF Martin
Jci Insight 7 (11), 2022
62022
ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment
JD Steimle, C Kim, M Rowton, RD Nadadur, Z Wang, M Stocker, ...
Cell reports 42 (6), 2023
32023
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages
M Rowton, C Perez-Cervantes, S Hur, J Jacobs-Li, E Lu, N Deng, ...
Developmental cell 57 (18), 2181-2203. e9, 2022
32022
LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation
IM Martínez Traverso, JD Steimle, X Zhao, J Wang, JF Martin
Development 149 (18), dev200860, 2022
32022
Regional and TBX5-Dependent Gene Expression in the Atria: Implications for Pulmonary Vein Development and Atrial Fibrillation
JD Steimle, B Laforest, RD Nadadur, MT Broman, IP Moskowitz
Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension …, 2020
22020
Correction: Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation
AD Hoffmann, XH Yang, O Burnicka-Turek, JD Bosman, X Ren, L Xie, ...
Plos Genetics 12 (12), e1006533, 2016
12016
Endothelial cells adopt a pro-reparative immune responsive signature during cardiac injury
H Long, JD Steimle, FJG Canozo, JH Kim, X Li, Y Morikawa, M Park, ...
Life Science Alliance 7 (2), 2024
2024
A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network
MT Broman, RD Nadadur, C Perez-Cervantes, O Burnicka-Turek, ...
Circulation, 2024
2024
Sweet and sour story of maternal diabetes and birth defects
JD Steimle, JF Martin
Nature Cardiovascular Research 2 (12), 1107-1108, 2023
2023
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