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Jesse Lai
Jesse Lai
Dewpoint Therapeutics, University of Southern California, Amgen, Queen's University
Verified email at dewpointx.com
Title
Cited by
Cited by
Year
Laboratory monitoring in emicizumab-treated persons with hemophilia A
J Müller, I Pekrul, B Pötzsch, B Berning, J Oldenburg, M Spannagl
Thrombosis and Haemostasis 119 (09), 1384-1393, 2019
842019
ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
KR Bowles, MC Silva, K Whitney, T Bertucci, JE Berlind, JD Lai, JC Garza, ...
Cell 184 (17), 4547-4563. e17, 2021
822021
The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity
LL Swystun, JD Lai, C Notley, I Georgescu, AS Paine, J Mewburn, ...
The Journal of clinical investigation 128 (9), 4057-4073, 2018
702018
Biological considerations of plasma-derived and recombinant factor VIII immunogenicity
J Lai, C Hough, J Tarrant, D Lillicrap
Blood, The Journal of the American Society of Hematology 129 (24), 3147-3154, 2017
472017
Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons
Y Shi, ST Hung, G Rocha, S Lin, GR Linares, KA Staats, C Seah, Y Wang, ...
JCI insight 4 (15), 2019
442019
The endothelial lectin clearance receptor CLEC4M binds and internalizes factor VIII in a VWF‐dependent and independent manner
LL Swystun, C Notley, I Georgescu, JD Lai, K Nesbitt, PD James, ...
Journal of Thrombosis and Haemostasis 17 (4), 681-694, 2019
432019
Factor VIII inhibitors: advances in basic and translational science
JD Lai, D Lillicrap
International Journal of Laboratory Hematology 39, 6-13, 2017
362017
Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A
JD Lai, PC Moorehead, K Sponagle, KN Steinitz, BM Reipert, C Hough, ...
Blood, The Journal of the American Society of Hematology 127 (26), 3439-3449, 2016
332016
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
ST Hung, GR Linares, WH Chang, Y Eoh, G Krishnan, S Mendonca, ...
Cell 186 (4), 786-802. e28, 2023
302023
N-linked glycosylation modulates the immunogenicity of recombinant human factor VIII in hemophilia A mice
JD Lai, LL Swystun, D Cartier, K Nesbitt, C Zhang, C Hough, JW Dennis, ...
Haematologica 103 (11), 1925, 2018
292018
C9ORF72 protein function and immune dysregulation in amyotrophic lateral sclerosis
JD Lai, JK Ichida
Neuroscience Letters 713, 134523, 2019
282019
The scavenger receptor SCARA5 is an endocytic receptor for von Willebrand factor expressed by littoral cells in the human spleen
LL Swystun, K Ogiwara, JD Lai, JRM Ojala, O Rawley, F Lassalle, ...
Journal of Thrombosis and Haemostasis 17 (8), 1384-1396, 2019
232019
Early cellular interactions and immune transcriptome profiles in human factor VIII‐exposed hemophilia A mice
JD Lai, D Cartier, RB Hartholt, LL Swystun, AS Van Velzen, ...
Journal of Thrombosis and Haemostasis 16 (3), 533-545, 2018
202018
To clear or to fear: An innate perspective on factor VIII immunity
JD Lai, MT Georgescu, C Hough, D Lillicrap
Cellular Immunology 301, 82-89, 2016
202016
Genetic connectivity across marginal habitats: the elephants of the Namib Desert
Y Ishida, PJ Van Coeverden de Groot, KEA Leggett, AS Putnam, VE Fox, ...
Ecology and Evolution 6 (17), 6189-6201, 2016
192016
War and peace: factor VIII and the adaptive immune response
MT Georgescu, JD Lai, C Hough, D Lillicrap
Cellular Immunology 301, 2-7, 2016
192016
A model of traumatic brain injury using human iPSC-derived cortical brain organoids
JD Lai, JE Berlind, G Fricklas, NS Maria, R Jacobs, V Yu, JK Ichida
BioRxiv, 2020.07. 05.180299, 2020
62020
KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury
JD Lai, JE Berlind, G Fricklas, C Lie, JP Urenda, K Lam, NS Maria, ...
Cell Stem Cell 31 (4), 519-536. e8, 2024
2024
Early mechanisms of factor VIII immunity in hemophilia A
J Lai
2017
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Articles 1–19