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Nitin A. Patil
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A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1
MA Hossain, M Kocan, ST Yao, SG Royce, VB Nair, C Siwek, NA Patil, ...
Chemical science 7 (6), 3805-3819, 2016
912016
Relaxin family peptides: structure–activity relationship studies
NA Patil, KJ Rosengren, F Separovic, JD Wade, RAD Bathgate, ...
British Journal of Pharmacology 174 (10), 950-961, 2017
792017
Cellular disulfide bond formation in bioactive peptides and proteins
NA Patil, J Tailhades, RA Hughes, F Separovic, JD Wade, MA Hossain
International journal of molecular sciences 16 (1), 1791-1805, 2015
622015
A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens
KD Roberts, Y Zhu, MAK Azad, ML Han, J Wang, L Wang, HH Yu, ...
Nature communications 13 (1), 1625, 2022
612022
The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1
A Sethi, S Bruell, N Patil, MA Hossain, DJ Scott, EJ Petrie, RAD Bathgate, ...
Nature communications 7 (1), 11344, 2016
532016
Intramolecular acyl transfer in peptide and protein ligation and synthesis
J Tailhades, NA Patil, MA Hossain, JD Wade
Journal of Peptide Science 21 (3), 139-147, 2015
482015
Polymyxins Bind to the Cell Surface of Unculturable Acinetobacter baumannii and Cause Unique Dependent Resistance
Y Zhu, J Lu, ML Han, X Jiang, MAK Azad, NA Patil, YW Lin, J Zhao, Y Hu, ...
Advanced Science 7 (15), 2000704, 2020
452020
Total chemical synthesis of an intra‐A‐chain cystathionine human insulin analogue with enhanced thermal stability
JA Karas, NA Patil, J Tailhades, MA Sani, DB Scanlon, BE Forbes, ...
Angewandte Chemie 128 (47), 14963-14967, 2016
442016
Minimum active structure of insulin-like peptide 5
A Belgi, RAD Bathgate, M Kocan, N Patil, S Zhang, GW Tregear, JD Wade, ...
Journal of Medicinal Chemistry 56 (23), 9509-9516, 2013
342013
Signal transduction pathways activated by insulin‐like peptide 5 at the relaxin family peptide RXFP4 receptor
SY Ang, DS Hutchinson, N Patil, BA Evans, RAD Bathgate, ML Halls, ...
British journal of pharmacology 174 (10), 1077-1089, 2017
312017
Amyloid aggregation and membrane activity of the antimicrobial peptide uperin 3.5
LL Martin, C Kubeil, S Piantavigna, T Tikkoo, NP Gray, T John, ...
Peptide Science 110 (3), e24052, 2018
292018
Engineering of a novel simplified human insulin-like peptide 5 agonist
NA Patil, RA Hughes, KJ Rosengren, M Kocan, SY Ang, J Tailhades, ...
Journal of medicinal chemistry 59 (5), 2118-2125, 2016
292016
Molecular dynamics simulations informed by membrane lipidomics reveal the structure–interaction relationship of polymyxins with the lipid A-based outer membrane of …
X Jiang, K Yang, B Yuan, M Han, Y Zhu, KD Roberts, NA Patil, J Li, ...
Journal of Antimicrobial Chemotherapy 75 (12), 3534-3543, 2020
252020
Combination of valproic acid and morpholino splice-switching oligonucleotide produces improved outcomes in spinal muscular atrophy patient-derived fibroblasts
A Farrelly-Rosch, CL Lau, N Patil, BJ Turner, F Shabanpoor
Neurochemistry International 108, 213-221, 2017
242017
2-Cyanoisonicotinamide conjugation: a facile approach to generate potent peptide inhibitors of the Zika virus protease
NA Patil, JP Quek, B Schroeder, R Morewood, J Rademann, D Luo, ...
ACS Medicinal Chemistry Letters 12 (5), 732-737, 2021
222021
The kinetics of amyloid fibrillar aggregation of uperin 3.5 is directed by the peptide’s secondary structure
T John, TJA Dealey, NP Gray, NA Patil, MA Hossain, B Abel, JA Carver, ...
Biochemistry 58 (35), 3656-3668, 2019
222019
Thiol-cyanobenzothiazole ligation for the efficient preparation of peptide–PNA conjugates
NA Patil, JA Karas, BJ Turner, F Shabanpoor
Bioconjugate Chemistry 30 (3), 793-799, 2019
212019
A One‐Pot Chemically Cleavable Bis‐Linker Tether Strategy for the Synthesis of Heterodimeric Peptides
NA Patil, J Tailhades, JA Karas, F Separovic, JD Wade, MA Hossain
Angewandte Chemie International Edition 55 (47), 14552-14556, 2016
212016
Adsorption of amyloidogenic peptides to functionalized surfaces is biased by charge and hydrophilicity
T John, GW Greene, NA Patil, TJA Dealey, MA Hossain, B Abel, LL Martin
Langmuir 35 (45), 14522-14531, 2019
202019
The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP4 receptor activity
NA Patil, RAD Bathgate, M Kocan, SY Ang, J Tailhades, F Separovic, ...
Amino Acids 48, 987-992, 2016
192016
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