| JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation. T Kallunki, B Su, I Tsigelny, HK Sluss, B Dérijard, G Moore, R Davis, ... Genes & development 8 (24), 2996-3007, 1994 | 835 | 1994 |
| Protein docking using continuum electrostatics and geometric fit JG Mandell, VA Roberts, ME Pique, V Kotlovyi, JC Mitchell, E Nelson, ... Protein engineering 14 (2), 105-113, 2001 | 420 | 2001 |
| Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases IF Tsigelny, L Crews, P Desplats, GM Shaked, Y Sharikov, H Mizuno, ... PloS one 3 (9), e3135, 2008 | 331 | 2008 |
| Cell-to-cell transmission of non-prion protein aggregates SJ Lee, P Desplats, C Sigurdson, I Tsigelny, E Masliah Nature Reviews Neurology 6 (12), 702-706, 2010 | 330 | 2010 |
| The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing D Comoletti, A De Jaco, LL Jennings, RE Flynn, G Gaietta, I Tsigelny, ... Journal of Neuroscience 24 (20), 4889-4893, 2004 | 289 | 2004 |
| Genomic landscape of cell-free DNA in patients with colorectal cancer JH Strickler, JM Loree, LG Ahronian, AR Parikh, D Niedzwiecki, ... Cancer discovery 8 (2), 164-173, 2018 | 254 | 2018 |
| Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism AA Chubykin, X Liu, D Comoletti, I Tsigelny, P Taylor, TC Sudhof Journal of Biological Chemistry 280 (23), 22365-22374, 2005 | 240 | 2005 |
| Dynamics of α‐synuclein aggregation and inhibition of pore‐like oligomer development by β‐synuclein IF Tsigelny, P Bar‐On, Y Sharikov, L Crews, M Hashimoto, MA Miller, ... The FEBS journal 274 (7), 1862-1877, 2007 | 214 | 2007 |
| Role of α‐synuclein penetration into the membrane in the mechanisms of oligomer pore formation IF Tsigelny, Y Sharikov, W Wrasidlo, T Gonzalez, PA Desplats, L Crews, ... The FEBS journal 279 (6), 1000-1013, 2012 | 208 | 2012 |
| Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1) WR Wikoff, MA Nagle, VL Kouznetsova, IF Tsigelny, SK Nigam Journal of proteome research 10 (6), 2842-2851, 2011 | 187 | 2011 |
| Role of the glycine triad in the ATP-binding site of cAMP-dependent protein kinase W Hemmer, M McGlone, I Tsigelny, SS Taylor Journal of Biological Chemistry 272 (27), 16946-16954, 1997 | 182 | 1997 |
| Fibrinogen signal transduction as a mediator and therapeutic target in inflammation: lessons from multiple sclerosis RA Adams, C Schachtrup, D Davalos, I Tsigelny, K Akassoglou Current medicinal chemistry 14 (27), 2925-2936, 2007 | 179 | 2007 |
| A de novo compound targeting α-synuclein improves deficits in models of Parkinson’s disease W Wrasidlo, IF Tsigelny, DL Price, G Dutta, E Rockenstein, TC Schwarz, ... Brain 139 (12), 3217-3236, 2016 | 147 | 2016 |
| p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway BD Sachs, GS Baillie, JR McCall, MA Passino, C Schachtrup, DA Wallace, ... The Journal of cell biology 177 (6), 1119-1132, 2007 | 146 | 2007 |
| Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein SB Hansen, Z Radić, TT Talley, BE Molles, T Deerinck, I Tsigelny, ... Journal of Biological Chemistry 277 (44), 41299-41302, 2002 | 129 | 2002 |
| Amino Acid Residues Controlling Reactivation of Organophosphonyl Conjugates of Acetylcholinesterase by Mono-and Bisquaternary Oximes (∗) Y Ashani, Z Radic, I Tsigelny, DC Vellom, NA Pickering, DM Quinn, ... Journal of Biological Chemistry 270 (11), 6370-6380, 1995 | 126 | 1995 |
| Kinetic analyses of mutations in the glycine-rich loop of cAMP-dependent protein kinase BD Grant, W Hemmer, I Tsigelny, JA Adams, SS Taylor Biochemistry 37 (21), 7708-7715, 1998 | 120 | 1998 |
| Role of synucleins in Alzheimer’s disease L Crews, I Tsigelny, M Hashimoto, E Masliah Neurotoxicity research 16, 306-317, 2009 | 109 | 2009 |
| Identification of the protein kinase A regulatory RIα-catalytic subunit interface by amide H/2H exchange and protein docking GS Anand, D Law, JG Mandell, AN Snead, I Tsigelny, SS Taylor, LFT Eyck, ... Proceedings of the National Academy of Sciences 100 (23), 13264-13269, 2003 | 107 | 2003 |
| Identification of Substituted Pyrimido[5,4-b]indoles as Selective Toll-Like Receptor 4 Ligands M Chan, T Hayashi, RD Mathewson, A Nour, Y Hayashi, S Yao, ... Journal of medicinal chemistry 56 (11), 4206-4223, 2013 | 98 | 2013 |
