| Redox signaling by reactive electrophiles and oxidants S Parvez, MJC Long, JR Poganik, Y Aye Chemical reviews 118 (18), 8798-8888, 2018 | 280 | 2018 |
| Universal DNA methylation age across mammalian tissues AT Lu, Z Fei, A Haghani, TR Robeck, JA Zoller, CZ Li, R Lowe, Q Yan, ... Nature aging, 1-23, 2023 | 170 | 2023 |
| On-demand targeting: investigating biology with proximity-directed chemistry MJC Long, JR Poganik, Y Aye Journal of the American Chemical Society 138 (11), 3610-3622, 2016 | 78 | 2016 |
| Biomarkers of aging for the identification and evaluation of longevity interventions M Moqri, C Herzog, JR Poganik, J Justice, DW Belsky, A Higgins-Chen, ... Cell 186 (18), 3758-3775, 2023 | 69 | 2023 |
| Biological age is increased by stress and restored upon recovery JR Poganik, B Zhang, GS Baht, A Tyshkovskiy, A Deik, C Kerepesi, ... Cell Metabolism 35 (5), 807-820. e5, 2023 | 69 | 2023 |
| Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1 JR Poganik, MJC Long, MT Disare, X Liu, SH Chang, T Hla, Y Aye The FASEB Journal 33 (12), 14636, 2019 | 48 | 2019 |
| DNA methylation networks underlying mammalian traits A Haghani, CZ Li, TR Robeck, J Zhang, AT Lu, J Ablaeva, ... Science 381 (6658), eabq5693, 2023 | 45* | 2023 |
| Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna AV Shindyapina, Y Cho, A Kaya, A Tyshkovskiy, JP Castro, A Deik, ... Science Advances 8 (37), eabo5482, 2022 | 44* | 2022 |
| β-TrCP1 is a vacillatory regulator of Wnt signaling MJ Long, HY Lin, S Parvez, Y Zhao, JR Poganik, P Huang, Y Aye Cell chemical biology 24 (8), 944-957. e7, 2017 | 41 | 2017 |
| Electrophile signaling and emerging immuno-and neuro-modulatory electrophilic pharmaceuticals JR Poganik, Y Aye Frontiers in Aging Neuroscience 12, 1, 2020 | 27 | 2020 |
| Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera JR Poganik, KT Huang, S Parvez, Y Zhao, S Raja, MJC Long, Y Aye Nature Communications 12 (1), 5736, 2021 | 25 | 2021 |
| Subcellular Redox Targeting: Bridging in Vitro and in Vivo Chemical Biology MJC Long, JR Poganik, S Ghosh, Y Aye ACS chemical biology 12 (3), 586-600, 2017 | 24 | 2017 |
| Getting the message? Native reactive electrophiles pass two out of three thresholds to be bona fide signaling mediators JR Poganik, MJC Long, Y Aye BioEssays 40 (5), 1700240, 2018 | 20 | 2018 |
| Interrogating precision electrophile signaling JR Poganik, MJC Long, Y Aye Trends in biochemical sciences 44 (4), 380-381, 2019 | 12 | 2019 |
| Validation of biomarkers of aging M Moqri, C Herzog, JR Poganik, K Ying, JN Justice, DW Belsky, ... Nature Medicine, 1-13, 2024 | 6 | 2024 |
| Z-REX uncovers a bifurcation in function of Keap1 paralogs A Van Hall-Beauvais, JR Poganik, KT Huang, S Parvez, Y Zhao, HY Lin, ... Elife 11, e83373, 2022 | 6 | 2022 |
| Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox … KT Huang, JR Poganik, S Parvez, S Raja, B Miller, MJC Long, JR Fetcho, ... Nature Protocols, 1-46, 2023 | 5* | 2023 |
| Epigenetic profiling and incidence of disrupted development point to gastrulation as aging ground zero in Xenopus laevis B Zhang, AE Tarkhov, W Ratzan, K Ying, M Moqri, JR Poganik, B Barre, ... bioRxiv, 2022.08. 02.502559, 2022 | 5 | 2022 |
| The mRNA‐binding protein HuR is a kinetically‐privileged electrophile sensor JR Poganik, AK Van Hall‐Beauvais, MJC Long, MT Disare, Y Zhao, Y Aye Helvetica Chimica Acta 103 (5), e2000041, 2020 | 5 | 2020 |
| We need to shift the focus of aging research to aging itself JR Poganik, VN Gladyshev Proceedings of the National Academy of Sciences 120 (37), e2307449120, 2023 | 4 | 2023 |
Saba ParvezAssistant Professor, Cell and Developmental Biology, Northwestern UniversityVerified email at northwestern.edu
