| Structure and biophysics of type III secretion in bacteria S Chatterjee, S Chaudhury, AC McShan, K Kaur, RN De Guzman Biochemistry 52 (15), 2508-2517, 2013 | 137 | 2013 |
| De novo design of a non-local β-sheet protein with high stability and accuracy E Marcos, TM Chidyausiku, AC McShan, T Evangelidis, S Nerli, L Carter, ... Nature structural & molecular biology 25 (11), 1028-1034, 2018 | 118 | 2018 |
| Hydrolysis of polysorbate 20 and 80 by a range of carboxylester hydrolases AC McShan, P Kei, JA Ji, D Kim, YJ Wang PDA Journal of Pharmaceutical Science and Technology, 2016 | 96 | 2016 |
| Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle AC McShan, K Natarajan, VK Kumirov, D Flores-Solis, J Jiang, ... Nature chemical biology 14 (8), 811-820, 2018 | 75 | 2018 |
| An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role K Natarajan, AC McShan, J Jiang, VK Kumirov, R Wang, H Zhao, ... Nature communications 8 (1), 15260, 2017 | 74 | 2017 |
| The role of molecular flexibility in antigen presentation and T cell receptor-mediated signaling K Natarajan, J Jiang, NA May, MG Mage, LF Boyd, AC McShan, ... Frontiers in immunology 9, 1657, 2018 | 68 | 2018 |
| The bacterial type III secretion system as a target for developing new antibiotics AC McShan, RN De Guzman Chemical biology & drug design 85 (1), 30-42, 2015 | 63 | 2015 |
| Chemical shift-based methods in NMR structure determination S Nerli, AC McShan, NG Sgourakis Progress in nuclear magnetic resonance spectroscopy 106, 1-25, 2018 | 59 | 2018 |
| NMR model of PrgI–sipd interaction and its implications in the needle-tip assembly of the Salmonella type III secretion system T Rathinavelan, M Lara-Tejero, M Lefebre, S Chatterjee, AC McShan, ... Journal of molecular biology 426 (16), 2958-2969, 2014 | 53 | 2014 |
| Computational design of closely related proteins that adopt two well-defined but structurally divergent folds KY Wei, D Moschidi, MJ Bick, S Nerli, AC McShan, LP Carter, PS Huang, ... Proceedings of the National Academy of Sciences 117 (13), 7208-7215, 2020 | 51 | 2020 |
| Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection AC McShan, CA Devlin, SA Overall, J Park, JS Toor, D Moschidi, ... Proceedings of the National Academy of Sciences 116 (51), 25602-25613, 2019 | 47 | 2019 |
| An order-to-disorder structural switch activates the FoxM1 transcription factor AH Marceau, CM Brison, S Nerli, HE Arsenault, AC McShan, E Chen, ... Elife 8, e46131, 2019 | 43 | 2019 |
| TAPBPR Promotes Antigen Loading on MHC-I Molecules Using a Peptide Trap A McShan, C Devlin, G Morozov, S Overall, D Moschidi, N Akella, ... Nature Communications 12, 2021 | 37 | 2021 |
| Backbone-independent NMR resonance assignments of methyl probes in large proteins S Nerli, VS De Paula, AC McShan, NG Sgourakis Nature communications 12 (1), 691, 2021 | 33 | 2021 |
| A recurrent mutation in anaplastic lymphoma kinase with distinct neoepitope conformations JS Toor, AA Rao, AC McShan, M Yarmarkovich, S Nerli, K Yamaguchi, ... Frontiers in Immunology 9, 99, 2018 | 33 | 2018 |
| Better together: Elements of successful scientific software development in a distributed collaborative community J Koehler Leman, BD Weitzner, PD Renfrew, SM Lewis, R Moretti, ... PLoS computational biology 16 (5), e1007507, 2020 | 31 | 2020 |
| TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules AC McShan, CA Devlin, GF Papadaki, Y Sun, AI Green, GI Morozov, ... Nature chemical biology 18 (8), 859-868, 2022 | 17 | 2022 |
| Characterization of the Binding of Hydroxyindole, Indoleacetic acid, and Morpholinoaniline to the Salmonella Type III Secretion System Proteins SipD and SipB AC McShan, A Anbanandam, S Patnaik, RN De Guzman ChemMedChem 11 (9), 963-971, 2016 | 17 | 2016 |
| De novo design of a homo-trimeric amantadine-binding protein J Park, B Selvaraj, AC McShan, SE Boyken, KY Wei, G Oberdorfer, ... Elife 8, e47839, 2019 | 16 | 2019 |
| NMR identification of the binding surfaces involved in the Salmonella and Shigella Type III secretion tip‐translocon protein–protein interactions AC McShan, K Kaur, S Chatterjee, KM Knight, RN De Guzman Proteins: Structure, Function, and Bioinformatics 84 (8), 1097-1107, 2016 | 10 | 2016 |
Nikolaos G. SgourakisUniversity of PennsylvaniaVerified email at pennmedicine.upenn.edu
