| Discovery of 5-(4-hydroxyphenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide as a neuroprotectant for Alzheimer’s disease by hybridization of curcumin and … JE Chojnacki, K Liu, X Yan, S Toldo, T Selden, M Estrada, ... ACS chemical neuroscience 5 (8), 690-699, 2014 | 88 | 2014 |
| Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: Synthesis, biological assessment, and molecular modeling A Samadi, M Estrada, C Pérez, MI Rodríguez-Franco, I Iriepa, I Moraleda, ... European journal of medicinal chemistry 57, 296-301, 2012 | 64 | 2012 |
| New cinnamic – N-benzylpiperidine and cinnamic – N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic … M Estrada, C Herrera-Arozamena, C Pérez, D Viña, A Romero, ... European journal of medicinal chemistry 121, 376-386, 2016 | 61 | 2016 |
| Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors J Reis, F Cagide, ME Valencia, J Teixeira, D Bagetta, C Perez, E Uriarte, ... European Journal of Medicinal Chemistry 158, 781-800, 2018 | 60 | 2018 |
| Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease ME Valencia, C Herrera-Arozamena, L de Andrés, C Pérez, ... European journal of medicinal chemistry 156, 534-553, 2018 | 44 | 2018 |
| Recent advances in neurogenic small molecules as innovative treatments for neurodegenerative diseases C Herrera-Arozamena, O Martí-Marí, M Estrada, M De la Fuente Revenga, ... Molecules 21 (9), 1165, 2016 | 38 | 2016 |
| Potent and selective MAO-B inhibitory activity: Amino-versus nitro-3-arylcoumarin derivatives MJ Matos, F Rodriguez-Enriquez, S Vilar, L Santana, E Uriarte, ... Bioorganic & Medicinal Chemistry Letters 25 (3), 642-648, 2015 | 32 | 2015 |
| New neurogenic lipoic-based hybrids as innovative Alzheimer's drugs with σ-1 agonism and β-secretase inhibition M Estrada, C Pérez, E Soriano, E Laurini, M Romano, S Pricl, ... Future Medicinal Chemistry 8 (11), 1191-1207, 2016 | 31 | 2016 |
| 3‐Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases MJ Matos, F Rodríguez‐Enríquez, F Borges, L Santana, E Uriarte, ... ChemMedChem 10 (12), 2071-2079, 2015 | 30 | 2015 |
| Regioselective synthesis of novel 4-aryl-2-ethylthio-7-methyl pyrazolo [1, 5-a]-[1, 3, 5]-triazines H Insuasty, M Estrada, E Cortés, J Quiroga, B Insuasty, R Abonía, ... Tetrahedron letters 47 (31), 5441-5443, 2006 | 29 | 2006 |
| PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice S Lorrio, A Romero, L González-Lafuente, R Lajarín-Cuesta, ... ACS Chemical Neuroscience 4 (9), 1267-1277, 2013 | 28 | 2013 |
| New flavonoid – N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties M Estrada-Valencia, C Herrera-Arozamena, C Pérez, D Viña, ... Journal of enzyme inhibition and medicinal chemistry 34 (1), 712-727, 2019 | 27 | 2019 |
| Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties C Herrera-Arozamena, M Estrada-Valencia, C Pérez, L Lagartera, ... European Journal of Medicinal Chemistry 190, 112090, 2020 | 17 | 2020 |
| Estudio preliminar de la citotoxicidad y la genotoxicidad de un extracto de origen vegetal conocido como palmo rosado en células meristemáticas de Allium cepa S Freyre, M Estrada, H Bolaños Memorias 5 (12), 12-17, 2009 | 15 | 2009 |
| Isolated molecules in 2-ethylsulfanyl-7-methyl-4-(4-methylphenyl) pyrazolo [1, 5-a][1, 3, 5] triazine and hydrogen-bonded sheets of R22 (10), R22 (16), R44 (22) and R44 (24 … H Insuasty, M Estrada, J Cobo, JN Low, C Glidewell Acta Crystallographica Section C: Crystal Structure Communications 62 (3 …, 2006 | 13 | 2006 |
| An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver AC Raquel Fernández-Ginés, José Antonio Encinar, John D. Hayes, Baldo Oliva ... Redox Biology 55, 102396, 2022 | 12 | 2022 |
| Synthesis and Biological Assessment of 4,1-Benzothiazepines with Neuroprotective Activity on the Ca2+ Overload for the Treatment of Neurodegenerative … L Viejo, M Rubio-Alarcón, RL Arribas, M Moreno-Castro, R Pérez-Marín, ... Molecules 26 (15), 4473, 2021 | 11 | 2021 |
| Resveratrol-based MTDLs to stimulate defensive and regenerative pathways and block early events in neurodegenerative cascades C Herrera-Arozamena, M Estrada-Valencia, P López-Caballero, C Pérez, ... Journal of Medicinal Chemistry 65 (6), 4727-4751, 2022 | 9 | 2022 |
| Optical control of muscular nicotinic channels with azocuroniums, photoswitchable azobenzenes bearing two N-methyl-N-carbocyclic quaternary ammonium groups C Herrera-Arozamena, M Estrada-Valencia, O Martí-Marí, C Pérez, ... European Journal of Medicinal Chemistry 200, 112403, 2020 | 7 | 2020 |
| Anticonvulsant profile of 2-ethylthio-7-methyl-4-(4-methylphenyl) pyrazolo [1, 5-a][1, 3, 5] triazine MH Estrada, H Insuasty, LE Cuca, M Marder, A Fierro, MF Guerrero Brazilian Journal of Pharmaceutical Sciences 50, 73-81, 2014 | 4 | 2014 |
Clara Herrera-ArozamenaUniversity of Leeds (School of Chemistry)Verified email at leeds.ac.uk
