C9orf72 expansion disrupts ATM-mediated chromosomal break repair C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ... Nature neuroscience 20 (9), 1225-1235, 2017 | 172 | 2017 |
SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair JJR Hudson, SC Chiang, OS Wells, C Rookyard, SF El-Khamisy Nature communications 3 (1), 733, 2012 | 92 | 2012 |
TEX264 coordinates p97-and SPRTN-mediated resolution of topoisomerase 1-DNA adducts J Fielden, K Wiseman, I Torrecilla, S Li, S Hume, SC Chiang, A Ruggiano, ... Nature communications 11 (1), 1274, 2020 | 79 | 2020 |
ATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cells M Alagoz, SC Chiang, A Sharma, SF El-Khamisy PloS one 8 (4), e58239, 2013 | 76 | 2013 |
TDP1 serine 81 promotes interaction with DNA ligase IIIα and facilitates cell survival following DNA damage SC Chiang, J Carroll, SF El-Khamisy Cell Cycle 9 (3), 588-595, 2010 | 75 | 2010 |
Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks C Kerzendorfer, A Whibley, G Carpenter, E Outwin, SC Chiang, G Turner, ... Human molecular genetics 19 (7), 1324-1334, 2010 | 74 | 2010 |
Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage SC Chiang, M Meagher, N Kassouf, M Hafezparast, PJ McKinnon, ... Science advances 3 (4), e1602506, 2017 | 60 | 2017 |
UCHL3 regulates topoisomerase-induced chromosomal break repair by controlling TDP1 proteostasis C Liao, R Beveridge, JJR Hudson, JD Parker, SC Chiang, S Ray, ... Cell reports 23 (11), 3352-3365, 2018 | 47 | 2018 |
Identification and characterisation of the BPI/LBP/PLUNC-like gene repertoire in chickens reveals the absence of a LBP gene SC Chiang, EJA Veldhuizen, FA Barnes, CJ Craven, HP Haagsman, ... Developmental & Comparative Immunology 35 (3), 285-295, 2011 | 41 | 2011 |
Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing J Carroll, TKW Page, SC Chiang, B Kalmar, D Bode, L Greensmith, ... Human molecular genetics 24 (3), 828-840, 2015 | 20 | 2015 |
Study of the mechanisms of crocetin‐induced differentiation and apoptosis in human acute promyelocytic leukemia cells M Moradzadeh, A Ghorbani, S Erfanian, ST Mohaddes, H Rahimi, ... Journal of cellular biochemistry 120 (2), 1943-1957, 2019 | 14 | 2019 |
Studying TDP1 function in DNA repair SC Chiang, K Liversidge, SF El-Khamisy DNA Topoisomerases: Methods and Protocols, 173-181, 2018 | 4 | 2018 |
UVA-induced carbon-centred radicals in lightly pigmented cells detected using ESR spectroscopy N Kassouf, CWM Kay, A Volkov, SC Chiang, MA Birch-Machin, ... Free Radical Biology and Medicine 126, 153-165, 2018 | 3 | 2018 |
Evolutionary History of PLUNCs: The Putative Pulmonary Mucosal Host Defence Proteins, SPLUNC1 and LPLUNC1 Are Present Only in the Therian Lineage. CD Bingle, S Chiang, EJ Veldhuizen, HP Haagsman, L Bingle, CJ Craven B32. MUCOSAL IMMUNITY AND AIRWAY EPITHELIA, A2816, 2009 | 1 | 2009 |
Middlesex University Research Repository N Kassouf, CWM Kay, A Volkov, SC Chiang, M Birch-Machin | | 2018 |
Investigating the role of Tyrosyl-DNA Phosphodiesterase 1 in nuclear and mitochondrial DNA repair SC Chiang University of Sussex, 2017 | | 2017 |
ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in M Alagoz, SC Chiang, A Sharma, SF El-Khamisy | | 2013 |
ASSOCIATION STUDIES ARTICLE C Kerzendorfer, A Whibley, G Carpenter, E Outwin, SC Chiang, G Turner, ... Human Molecular Genetics 19 (7), 2010 | | 2010 |