| Creating new fluorescent probes for cell biology J Zhang, RE Campbell, AY Ting, RY Tsien Nature reviews Molecular cell biology 3 (12), 906-918, 2002 | 2504 | 2002 |
| Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering J Zhang, Y Ma, SS Taylor, RY Tsien Proceedings of the National Academy of Sciences 98 (26), 14997-15002, 2001 | 721 | 2001 |
| A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C JD Violin, J Zhang, RY Tsien, AC Newton The Journal of cell biology 161 (5), 899-909, 2003 | 640 | 2003 |
| The growing and glowing toolbox of fluorescent and photoactive proteins EA Rodriguez, RE Campbell, JY Lin, MZ Lin, A Miyawaki, AE Palmer, ... Trends in biochemical sciences 42 (2), 111-129, 2017 | 608 | 2017 |
| Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments LM DiPilato, X Cheng, J Zhang Proceedings of the National Academy of Sciences 101 (47), 16513-16518, 2004 | 566 | 2004 |
| SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2 Y Lei, J Zhang, CR Schiavon, M He, L Chen, H Shen, Y Zhang, Q Yin, ... Circulation research 128 (9), 1323-1326, 2021 | 539 | 2021 |
| Genetically encodable fluorescent biosensors for tracking signaling dynamics in living cells RH Newman, MD Fosbrink, J Zhang Chemical reviews 111 (5), 3614-3666, 2011 | 381 | 2011 |
| Genetically encoded fluorescent biosensors illuminate the spatiotemporal regulation of signaling networks EC Greenwald, S Mehta, J Zhang Chemical reviews 118 (24), 11707-11794, 2018 | 376 | 2018 |
| Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes J Zhang, CJ Hupfeld, SS Taylor, JM Olefsky, RY Tsien Nature 437 (7058), 569-573, 2005 | 372 | 2005 |
| Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters MD Allen, J Zhang Biochemical and biophysical research communications 348 (2), 716-721, 2006 | 347 | 2006 |
| A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN M Rahdar, T Inoue, T Meyer, J Zhang, F Vazquez, PN Devreotes Proceedings of the National Academy of Sciences 106 (2), 480-485, 2009 | 318 | 2009 |
| β2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics JD Violin, LM DiPilato, N Yildirim, TC Elston, J Zhang, RJ Lefkowitz Journal of Biological Chemistry 283 (5), 2949-2961, 2008 | 280 | 2008 |
| Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter MT Kunkel, Q Ni, RY Tsien, J Zhang, AC Newton Journal of Biological Chemistry 280 (7), 5581-5587, 2005 | 267 | 2005 |
| PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains X Gao, PR Lowry, X Zhou, C Depry, Z Wei, GW Wong, J Zhang Proceedings of the National Academy of Sciences 108 (35), 14509-14514, 2011 | 226 | 2011 |
| Widely accessible method for superresolution fluorescence imaging of living systems P Dedecker, GCH Mo, T Dertinger, J Zhang Proceedings of the National Academy of Sciences 109 (27), 10909-10914, 2012 | 220 | 2012 |
| Visualization of PKA activity in plasma membrane microdomains C Depry, MD Allen, J Zhang Molecular bioSystems 7 (1), 52-58, 2011 | 217 | 2011 |
| Phase separation of a PKA regulatory subunit controls cAMP compartmentation and oncogenic signaling JZ Zhang, TW Lu, LM Stolerman, B Tenner, JR Yang, JF Zhang, M Falcke, ... Cell 182 (6), 1531-1544. e15, 2020 | 198 | 2020 |
| A genetically encoded near-infrared fluorescent calcium ion indicator Y Qian, KD Piatkevich, B Mc Larney, AS Abdelfattah, S Mehta, ... Nature methods 16 (2), 171-174, 2019 | 195 | 2019 |
| Construction of human activity‐based phosphorylation networks RH Newman, J Hu, HS Rho, Z Xie, C Woodard, J Neiswinger, C Cooper, ... Molecular systems biology 9 (1), 655, 2013 | 185 | 2013 |
| Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes JJ Saucerman, J Zhang, JC Martin, LX Peng, AE Stenbit, RY Tsien, ... Proceedings of the National Academy of Sciences 103 (34), 12923-12928, 2006 | 181 | 2006 |
