| Import of a cytosolic protein into lysosomes by chaperone-mediated autophagy depends on its folding state N Salvador, C Aguado, M Horst, E Knecht Journal of Biological Chemistry 275 (35), 27447-27456, 2000 | 290 | 2000 |
| Laforin, the most common protein mutated in Lafora disease, regulates autophagy C Aguado, S Sarkar, VI Korolchuk, O Criado, S Vernia, P Boya, P Sanz, ... Human molecular genetics 19 (14), 2867-2876, 2010 | 196 | 2010 |
| Regulation of glycogen synthesis by the laforin–malin complex is modulated by the AMP-activated protein kinase pathway MC Solaz-Fuster, JV Gimeno-Alcaniz, S Ros, ME Fernandez-Sanchez, ... Human molecular genetics 17 (5), 667-678, 2008 | 163 | 2008 |
| Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy O Criado, C Aguado, J Gayarre, L Duran-Trio, AM Garcia-Cabrero, ... Human molecular genetics 21 (7), 1521-1533, 2012 | 150 | 2012 |
| Alterations in ROS activity and lysosomal pH account for distinct patterns of macroautophagy in LINCL and JNCL fibroblasts JM Vidal-Donet, J Carcel-Trullols, B Casanova, C Aguado, E Knecht PLoS One 8 (2), e55526, 2013 | 107 | 2013 |
| Intracellular protein degradation in mammalian cells: recent developments E Knecht, C Aguado, J Cárcel, I Esteban, JM Esteve, G Ghislat, JF Moruno, ... Cellular and Molecular Life Sciences 66, 2427-2443, 2009 | 107 | 2009 |
| Dynamics of an F-actin aggresome generated by the actin-stabilizing toxin jasplakinolide F Lázaro-Diéguez, C Aguado, E Mato, Y Sánchez-Ruíz, I Esteban, ... Journal of cell science 121 (9), 1415-1425, 2008 | 90 | 2008 |
| Role of AMP-activated protein kinase in autophagy and proteasome function R Viana, C Aguado, I Esteban, D Moreno, B Viollet, E Knecht, P Sanz Biochemical and biophysical research communications 369 (3), 964-968, 2008 | 89 | 2008 |
| PTEN increases autophagy and inhibits the ubiquitin-proteasome pathway in glioma cells independently of its lipid phosphatase activity R Errafiy, C Aguado, G Ghislat, JM Esteve, A Gil, M Loutfi, E Knecht PloS one 8 (12), e83318, 2013 | 81 | 2013 |
| Characterization of human GTPBP3, a GTP-binding protein involved in mitochondrial tRNA modification M Villarroya, S Prado, JM Esteve, MA Soriano, C Aguado, ... Molecular and cellular biology 28 (24), 7514-7531, 2008 | 71 | 2008 |
| Increased oxidative stress and impaired antioxidant response in Lafora disease C Romá-Mateo, C Aguado, JL García-Giménez, JS Ibáñez-Cabellos, ... Molecular neurobiology 51, 932-946, 2015 | 64 | 2015 |
| The GTPase activity and C-terminal cysteine of the Escherichia coli MnmE protein are essential for its tRNA modifying function L Yim, M Martínez-Vicente, M Villarroya, C Aguado, E Knecht, ... Journal of Biological Chemistry 278 (31), 28378-28387, 2003 | 62 | 2003 |
| Annexin A5 stimulates autophagy and inhibits endocytosis G Ghislat, C Aguado, E Knecht Journal of Cell Science 125 (1), 92-107, 2012 | 61 | 2012 |
| Reactive glia-derived neuroinflammation: a novel hallmark in Lafora progressive myoclonus epilepsy that progresses with age M Lahuerta, D Gonzalez, C Aguado, A Fathinajafabadi, ... Molecular neurobiology 57, 1607-1621, 2020 | 47 | 2020 |
| Impaired autophagy in Lafora disease E Knecht, C Aguado, S Sarkar, VI Korolchuk, O Criado-García, S Vernia, ... Autophagy 6 (7), 991-993, 2010 | 47 | 2010 |
| Transglutaminase activity is involved in Saccharomyces cerevisiae wall construction M Iranzo, C Aguado, C Pallotti, JV Cañizares, S Mormeneo Microbiology 148 (5), 1329-1334, 2002 | 47 | 2002 |
| The phosphatase activity of laforin is dispensable to rescue Epm2a−/− mice from Lafora disease J Gayarre, L Duran-Trío, O Criado Garcia, C Aguado, L Juana-López, ... Brain 137 (3), 806-818, 2014 | 46 | 2014 |
| Autophagy induction halts axonal degeneration in a mouse model of X-adrenoleukodystrophy N Launay, C Aguado, S Fourcade, M Ruiz, L Grau, J Riera, C Guilera, ... Acta neuropathologica 129, 399-415, 2015 | 45 | 2015 |
| Extracellular histones activate autophagy and apoptosis via mTOR signaling in human endothelial cells JS Ibañez-Cabellos, C Aguado, D Perez-Cremades, JL García-Giménez, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (10 …, 2018 | 42 | 2018 |
| Oxidative stress, a new hallmark in the pathophysiology of Lafora progressive myoclonus epilepsy C Roma-Mateo, C Aguado, JL García-Giménez, E Knecht, P Sanz, ... Free Radical Biology and Medicine 88, 30-41, 2015 | 38 | 2015 |
Erwin KnechtCentro de Investigación Príncipe FelipeVerified email at cipf.es
