| Identification of a nuclear receptor for bile acids M Makishima, AY Okamoto, JJ Repa, H Tu, RM Learned, A Luk, MV Hull, ... Science 284 (5418), 1362-1365, 1999 | 3052 | 1999 |
| Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response CS Manno, GF Pierce, VR Arruda, B Glader, M Ragni, JJE Rasko, ... Nature medicine 12 (3), 342-347, 2006 | 2377 | 2006 |
| Role of LXRs in control of lipogenesis JR Schultz, H Tu, A Luk, JJ Repa, JC Medina, L Li, S Schwendner, ... Genes & development 14 (22), 2831-2838, 2000 | 2001 | 2000 |
| Hemophilia B gene therapy with a high-specific-activity factor IX variant LA George, SK Sullivan, A Giermasz, JEJ Rasko, BJ Samelson-Jones, ... New England Journal of Medicine 377 (23), 2215-2227, 2017 | 705 | 2017 |
| Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR J Ou, H Tu, B Shan, A Luk, RA DeBose-Boyd, Y Bashmakov, JL Goldstein, ... Proceedings of the National Academy of Sciences 98 (11), 6027-6032, 2001 | 601 | 2001 |
| Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A J Mahlangu, JS Powell, MV Ragni, P Chowdary, NC Josephson, ... Blood, The Journal of the American Society of Hematology 123 (3), 317-325, 2014 | 517 | 2014 |
| Ethanol intoxication in Drosophila: genetic and pharmacological evidence for regulation by the cAMP signaling pathway MS Moore, J DeZazzo, AY Luk, T Tully, CM Singh, U Heberlein Cell 93 (6), 997-1007, 1998 | 502 | 1998 |
| Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B JS Powell, KJ Pasi, MV Ragni, MC Ozelo, LA Valentino, JN Mahlangu, ... New England Journal of Medicine 369 (24), 2313-2323, 2013 | 378 | 2013 |
| Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients JS Powell, NC Josephson, D Quon, MV Ragni, G Cheng, E Li, H Jiang, ... Blood, The Journal of the American Society of Hematology 119 (13), 3031-3037, 2012 | 328 | 2012 |
| Growth and differentiation in the Drosophila eye coordinated by hedgehog U Heberlein, CM Singh, AY Luk, TJ Donohoe Nature 373 (6516), 709-711, 1995 | 258 | 1995 |
| Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients AD Shapiro, MV Ragni, LA Valentino, NS Key, NC Josephson, JS Powell, ... Blood, The Journal of the American Society of Hematology 119 (3), 666-672, 2012 | 257 | 2012 |
| Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B H Jiang, GF Pierce, MC Ozelo, EV De Paula, JA Vargas, P Smith, ... Molecular Therapy 14 (3), 452-455, 2006 | 248 | 2006 |
| eyelidantagonizes wingless signaling during Drosophiladevelopment and has homology to the Bright family of DNA-binding proteins JE Treisman, A Luk, GM Rubin, U Heberlein Genes & development 11 (15), 1949-1962, 1997 | 121 | 1997 |
| Factor VIII-Fc chimeric and hybrid polypeptides, and methods of use thereof JA Dumont, S Low, AJ Bitonti, G Pierce, A Luk, H Jiang, B McKinney, ... US Patent 9,050,318, 2015 | 97 | 2015 |
| Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A JS Powell, DJ Nugent, JA Harrison, A Soni, A Luk, H Stass, E Gorina Journal of Thrombosis and Haemostasis 6 (2), 277-283, 2008 | 73 | 2008 |
| Factor VIII-Fc chimeric and hybrid polypeptides, and methods of use thereof JA Dumont, S Low, AJ Bitonti, G Pierce, A Luk, H Jiang, B McKinney, ... US Patent 9,241,978, 2016 | 71 | 2016 |
| Factor viii chimeric and hybrid polypeptides, and methods of use thereof JA Dumont, S Low, AJ Bitonti, G Pierce, A Luk, H Jiang, B Mckinney, ... | 67 | 2013 |
| Long‐acting recombinant factor IX Fc fusion protein (rFIXF c) for perioperative management of subjects with haemophilia B in the phase 3 B‐LONG study JS Powell, S Apte, H Chambost, C Hermans, S Jackson, NC Josephson, ... British journal of haematology 168 (1), 124-134, 2015 | 56 | 2015 |
| A screen for dominant modifiers of roDom, a mutation that disrupts morphogenetic furrow progression in Drosophila, identifies Groucho and Hairless as regulators of atonal … F Chanut, A Luk, U Heberlein Genetics 156 (3), 1203-1217, 2000 | 34 | 2000 |
| Immune responses to AAV and to factor IX in a phase I study of AAV-mediated, liver-directed gene transfer for hemophilia B K High, C Manno, D Sabatino, S Hutchison, M Dake, M Razavi, R Kaye, ... Molecular Therapy 9, S383-S384, 2004 | 31 | 2004 |
