Inactivation of Glucosamine‐6‐Phosphate Synthase by N3‐Oxoacyl Derivatives of L‐2,3‐Diaminopropanoic Acid R Jędrzejczak, M Wojciechowski, R Andruszkiewicz, P Sowiński, ... ChemBioChem 13 (1), 85-96, 2012 | 679* | 2012 |
The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1 Y Cao, Y Liang, K Tanaka, CT Nguyen, RP Jedrzejczak, A Joachimiak, ... elife 3, e03766, 2014 | 596 | 2014 |
Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography DW Kneller, G Phillips, HM O’Neill, R Jedrzejczak, L Stols, P Langan, ... Nature communications 11 (1), 3202, 2020 | 372 | 2020 |
Crystal structure of Nsp15 endoribonuclease NendoU from SARS‐CoV‐2 Y Kim, R Jedrzejczak, NI Maltseva, M Wilamowski, M Endres, A Godzik, ... Protein Science 29 (7), 1596-1605, 2020 | 363 | 2020 |
Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors J Osipiuk, SA Azizi, S Dvorkin, M Endres, R Jedrzejczak, KA Jones, ... Nature communications 12 (1), 743, 2021 | 345 | 2021 |
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ... Science 373 (6557), 931-936, 2021 | 186 | 2021 |
A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase S Wellington, PP Nag, K Michalska, SE Johnston, RP Jedrzejczak, ... Nature chemical biology 13 (9), 943-950, 2017 | 123 | 2017 |
Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets HL Dugan, CT Stamper, L Li, S Changrob, NW Asby, PJ Halfmann, ... Immunity 54 (6), 1290-1303. e7, 2021 | 110 | 2021 |
Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2 Y Kim, J Wower, N Maltseva, C Chang, R Jedrzejczak, M Wilamowski, ... Communications biology 4 (1), 193, 2021 | 109 | 2021 |
Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes K Michalska, Y Kim, R Jedrzejczak, NI Maltseva, L Stols, M Endres, ... IUCrJ 7 (5), 814-824, 2020 | 99 | 2020 |
The crystal structure of nsp10-nsp16 heterodimer from SARS-CoV-2 in complex with S-adenosylmethionine M Rosas-Lemus, G Minasov, L Shuvalova, NL Inniss, O Kiryukhina, ... BioRxiv, 2020 | 67 | 2020 |
New LIC vectors for production of proteins from genes containing rare codons WH Eschenfeldt, M Makowska-Grzyska, L Stols, MI Donnelly, ... Journal of structural and functional genomics 14, 135-144, 2013 | 58 | 2013 |
2′-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography M Wilamowski, DA Sherrell, G Minasov, Y Kim, L Shuvalova, A Lavens, ... Proceedings of the National Academy of Sciences 118 (21), e2100170118, 2021 | 55 | 2021 |
The crystal structure of papain-like protease of SARS CoV-2 J Osipiuk, R Jedrzejczak, C Tesar, M Endres, L Stols, G Babnigg, Y Kim, ... RSCB PDB 10, 2020 | 48 | 2020 |
Interaction of antidiabetic α‐glucosidase inhibitors and gut bacteria α‐glucosidase K Tan, C Tesar, R Wilton, RP Jedrzejczak, A Joachimiak Protein Science 27 (8), 1498-1508, 2018 | 48 | 2018 |
Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication M Wilamowski, M Hammel, W Leite, Q Zhang, Y Kim, KL Weiss, ... Biophysical journal 120 (15), 3152-3165, 2021 | 43 | 2021 |
Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro N Drayman, KA Jones, SA Azizi, HM Froggatt, K Tan, NI Maltseva, S Chen, ... BioRxiv, 2020.08. 31.274639, 2020 | 42 | 2020 |
A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor RK Jha, TL Kern, Y Kim, C Tesar, R Jedrzejczak, A Joachimiak, ... Nucleic Acids Research 44 (17), 8490-8500, 2016 | 34 | 2016 |
Structure of Calcarisporiella thermophila Hsp104 disaggregase that antagonizes diverse proteotoxic misfolding events K Michalska, K Zhang, ZM March, C Hatzos-Skintges, G Pintilie, L Bigelow, ... Structure 27 (3), 449-463. e7, 2019 | 33 | 2019 |
The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily G Batot, K Michalska, G Ekberg, EM Irimpan, G Joachimiak, R Jedrzejczak, ... Nucleic acids research 45 (9), 5013-5025, 2017 | 30 | 2017 |