| Clinical mechanism of the cystic fibrosis transmembrane conductance regulator potentiator ivacaftor in G551D-mediated cystic fibrosis SM Rowe, SL Heltshe, T Gonska, SH Donaldson, D Borowitz, D Gelfond, ... American journal of respiratory and critical care medicine 190 (2), 175-184, 2014 | 522 | 2014 |
| Type of CFTR mutation determines risk of pancreatitis in patients with cystic fibrosis CY Ooi, R Dorfman, M Cipolli, T Gonska, C Castellani, K Keenan, ... Gastroenterology 140 (1), 153-161, 2011 | 277 | 2011 |
| Risk factors associated with pediatric acute recurrent and chronic pancreatitis: lessons from INSPPIRE S Kumar, CY Ooi, S Werlin, M Abu-El-Haija, B Barth, MD Bellin, PR Durie, ... JAMA pediatrics 170 (6), 562-569, 2016 | 258 | 2016 |
| Management of acute pancreatitis in the pediatric population: a clinical report from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition … M Abu-El-Haija, S Kumar, JA Quiros, K Balakrishnan, B Barth, S Bitton, ... Journal of pediatric gastroenterology and nutrition 66 (1), 159-176, 2018 | 236 | 2018 |
| Pediatric chronic pancreatitis is associated with genetic risk factors and substantial disease burden SJ Schwarzenberg, M Bellin, SZ Husain, M Ahuja, B Barth, H Davis, ... The Journal of pediatrics 166 (4), 890-896. e1, 2015 | 192 | 2015 |
| CFTR Cl− channel function in native human colon correlates with the genotype and phenotype in cystic fibrosis S Hirtz, T Gonska, HH Seydewitz, J Thomas, P Greiner, J Kuehr, ... Gastroenterology 127 (4), 1085-1095, 2004 | 156 | 2004 |
| Inconclusive diagnosis of cystic fibrosis after newborn screening CY Ooi, C Castellani, K Keenan, J Avolio, S Volpi, M Boland, T Kovesi, ... Pediatrics 135 (6), e1377-e1385, 2015 | 141 | 2015 |
| Modulation of Ca2+-activated Cl− secretion by basolateral K+ channels in human normal and cystic fibrosis airway epithelia M Mall, T Gonska, J Thomas, R Schreiber, HH Seydewitz, J Kuehr, ... Pediatric research 53 (4), 608-618, 2003 | 135 | 2003 |
| Severe ulcerative colitis after rituximab therapy DS Ardelean, T Gonska, S Wires, E Cutz, A Griffiths, E Harvey, SML Tse, ... Pediatrics 126 (1), e243-e246, 2010 | 134 | 2010 |
| Cystic fibrosis transmembrane conductance regulator-related metabolic syndrome and cystic fibrosis screen positive, inconclusive diagnosis CL Ren, DS Borowitz, T Gonska, MS Howenstine, H Levy, J Massie, ... The Journal of Pediatrics 181, S45-S51. e1, 2017 | 129 | 2017 |
| Inhibition of Amiloride-Sensitive Epithelial Na+ Absorption by Extracellular Nucleotides in Human Normal and Cystic Fibrosis Airways M Mall, A Wissner, T Gonska, D Calenborn, J Kuehr, M Brandis, ... American journal of respiratory cell and molecular biology 23 (6), 755-761, 2000 | 128 | 2000 |
| Rescue of multiple class II CFTR mutations by elexacaftor+ tezacaftor+ ivacaftor mediated in part by the dual activities of elexacaftor as both corrector and potentiator O Laselva, C Bartlett, TNA Gunawardena, H Ouyang, PDW Eckford, ... European Respiratory Journal 57 (6), 2021 | 122 | 2021 |
| Impact of CFTR modulation with ivacaftor on gut microbiota and intestinal inflammation CY Ooi, SA Syed, L Rossi, M Garg, B Needham, J Avolio, K Young, ... Scientific reports 8 (1), 17834, 2018 | 118 | 2018 |
| VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface PDW Eckford, M Ramjeesingh, S Molinski, S Pasyk, JF Dekkers, C Li, ... Chemistry & biology 21 (5), 666-678, 2014 | 113 | 2014 |
| Cystic fibrosis gene modifier SLC26A9 modulates airway response to CFTR-directed therapeutics LJ Strug, T Gonska, G He, K Keenan, W Ip, PY Boelle, F Lin, N Panjwani, ... Human molecular genetics 25 (20), 4590-4600, 2016 | 110 | 2016 |
| The intestinal epithelial insulin-like growth factor-1 receptor links glucagon-like peptide-2 action to gut barrier function CX Dong, W Zhao, C Solomon, KJ Rowland, C Ackerley, S Robine, ... Endocrinology 155 (2), 370-379, 2014 | 108 | 2014 |
| Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue SV Molinski, S Ahmadi, W Ip, H Ouyang, A Villella, JP Miller, PS Lee, ... EMBO molecular medicine 9 (9), 1224-1243, 2017 | 106 | 2017 |
| GOAL Investigators of the Cystic Fibrosis Foundation Therapeutics Development Network. Clinical mechanism of the cystic fibrosis transmembrane conductance regulator potentiator … SM Rowe, SL Heltshe, T Gonska, SH Donaldson, D Borowitz, D Gelfond, ... Am J Respir Crit Care Med 190 (2), 175-84, 2014 | 104 | 2014 |
| Bacterial overgrowth, dysbiosis, inflammation, and dysmotility in the Cystic Fibrosis intestine J Dorsey, T Gonska Journal of Cystic Fibrosis 16, S14-S23, 2017 | 102 | 2017 |
| β-adrenergic sweat secretion as a diagnostic test for cystic fibrosis P Quinton, L Molyneux, W Ip, A Dupuis, J Avolio, E Tullis, D Conrad, ... American journal of respiratory and critical care medicine 186 (8), 732-739, 2012 | 99 | 2012 |
