Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse MC Thomas, RJ Pickering, D Tsorotes, A Koitka, K Sheehy, S Bernardi, ... Circulation research 107 (7), 888-897, 2010 | 284 | 2010 |
Protective effect of let-7 miRNA family in regulating inflammation in diabetes-associated atherosclerosis E Brennan, B Wang, A McClelland, M Mohan, M Marai, O Beuscart, ... Diabetes 66 (8), 2266-2277, 2017 | 163 | 2017 |
Recent novel approaches to limit oxidative stress and inflammation in diabetic complications RJ Pickering, CJ Rosado, A Sharma, S Buksh, M Tate, JB de Haan Clinical & translational immunology 7 (4), e1016, 2018 | 162 | 2018 |
Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function AG Miller, G Tan, KJ Binger, RJ Pickering, MC Thomas, RH Nagaraj, ... Diabetes 59 (12), 3208-3215, 2010 | 123 | 2010 |
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice P Pymm, A Adair, LJ Chan, JP Cooney, FL Mordant, CC Allison, E Lopez, ... Proceedings of the National Academy of Sciences 118 (19), e2101918118, 2021 | 112 | 2021 |
Transient intermittent hyperglycemia accelerates atherosclerosis by promoting myelopoiesis MC Flynn, MJ Kraakman, C Tikellis, MKS Lee, NMJ Hanssen, ... Circulation research 127 (7), 877-892, 2020 | 99 | 2020 |
Dicarbonyl stress in the absence of hyperglycemia increases endothelial inflammation and atherogenesis similar to that observed in diabetes C Tikellis, RJ Pickering, D Tsorotes, O Huet, ME Cooper, ... Diabetes 63 (11), 3915-3925, 2014 | 94 | 2014 |
Relationship between levels of advanced glycation end products and their soluble receptor and adverse outcomes in adults with type 2 diabetes MC Thomas, M Woodward, B Neal, Q Li, R Pickering, M Marre, B Williams, ... Diabetes Care 38 (10), 1891-1897, 2015 | 89 | 2015 |
Osteoprotegerin promotes vascular fibrosis via a TGF-β1 autocrine loop B Toffoli, RJ Pickering, D Tsorotes, B Wang, S Bernardi, P Kantharidis, ... Atherosclerosis 218 (1), 61-68, 2011 | 77 | 2011 |
Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis RJ Pickering, C Tikellis, CJ Rosado, D Tsorotes, A Dimitropoulos, M Smith, ... The Journal of clinical investigation 129 (1), 406-421, 2019 | 76 | 2019 |
Alagebrium reduces glomerular fibrogenesis and inflammation beyond preventing RAGE activation in diabetic apolipoprotein E knockout mice AMD Watson, SP Gray, L Jiaze, A Soro-Paavonen, B Wong, ME Cooper, ... Diabetes 61 (8), 2105-2113, 2012 | 71 | 2012 |
Interaction of diabetes and ACE2 in the pathogenesis of cardiovascular disease in experimental diabetes C Tikellis, R Pickering, D Tsorotes, XJ Du, H Kiriazis, TP Nguyen-Huu, ... Clinical science 123 (8), 519-529, 2012 | 68 | 2012 |
Measles virus hemagglutinin protein expressed in transgenic lettuce induces neutralising antibodies in mice following mucosal vaccination DE Webster, SD Smith, RJ Pickering, RA Strugnell, IB Dry, SL Wesselingh Vaccine 24 (17), 3538-3544, 2006 | 68 | 2006 |
Lipoxins protect against inflammation in diabetes-associated atherosclerosis EP Brennan, M Mohan, A McClelland, M De Gaetano, C Tikellis, M Marai, ... Diabetes 67 (12), 2657-2667, 2018 | 66 | 2018 |
Activation of the Renin-Angiotensin system mediates the effects of dietary salt intake on atherogenesis in the apolipoprotein E knockout mouse C Tikellis, RJ Pickering, D Tsorotes, O Huet, J Chin-Dusting, ME Cooper, ... Hypertension 60 (1), 98-105, 2012 | 60 | 2012 |
Lipoxins regulate the early growth response–1 network and reverse diabetic kidney disease EP Brennan, M Mohan, A McClelland, C Tikellis, M Ziemann, A Kaspi, ... Journal of the American Society of Nephrology 29 (5), 1437-1448, 2018 | 53 | 2018 |
ACE2 deficiency shifts energy metabolism towards glucose utilization S Bernardi, C Tikellis, R Candido, D Tsorotes, RJ Pickering, F Bossi, ... Metabolism 64 (3), 406-415, 2015 | 51 | 2015 |
Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium A Sharma, D Yuen, O Huet, R Pickering, N Stefanovic, P Bernatchez, ... Vascular Pharmacology 79, 32-42, 2016 | 45 | 2016 |
The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy MJ De Blasio, A Ramalingam, AH Cao, D Prakoso, JM Ye, R Pickering, ... European journal of pharmacology 807, 12-20, 2017 | 44 | 2017 |
Short-term treatment with diminazene aceturate ameliorates the reduction in kidney ACE2 activity in rats with subtotal nephrectomy E Velkoska, SK Patel, K Griggs, RJ Pickering, C Tikellis, LM Burrell PLoS One 10 (3), e0118758, 2015 | 43 | 2015 |