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Christopher R McCurdy
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A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity
S Khan, X Zhang, D Lv, Q Zhang, Y He, P Zhang, X Liu, D Thummuri, ...
Nature medicine 25 (12), 1938-1947, 2019
3982019
Self‐treatment of opioid withdrawal using kratom (Mitragynia speciosa korth)
EW Boyer, KM Babu, JE Adkins, CR McCurdy, JH Halpern
Addiction 103 (6), 1048-1050, 2008
3872008
Opioid receptors and legal highs: Salvia divinorum and Kratom
KM Babu, CR McCurdy, EW Boyer
Clinical toxicology 46 (2), 146-152, 2008
3002008
Analgesic substances derived from natural products (natureceuticals)
CR McCurdy, SS Scully
Life sciences 78 (5), 476-484, 2005
1792005
Antinociceptive profile of salvinorin A, a structurally unique kappa opioid receptor agonist
CR McCurdy, KJ Sufka, GH Smith, JE Warnick, MJ Nieto
Pharmacology Biochemistry and Behavior 83 (1), 109-113, 2006
1662006
Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of 1-deoxy-D-xylulose-5-phosphate …
N Singh, G Chevé, MA Avery, CR McCurdy
Current pharmaceutical design 13 (11), 1161-1177, 2007
1532007
p-Hydroxyphenylpyruvate dioxygenase is a herbicidal target site for β-triketones from Leptospermum scoparium
FE Dayan, SO Duke, A Sauldubois, N Singh, C McCurdy, C Cantrell
Phytochemistry 68 (14), 2004-2014, 2007
1462007
Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7‐hydroxymitragynine
SE Hemby, S McIntosh, F Leon, SJ Cutler, CR McCurdy
Addiction biology 24 (5), 874-885, 2019
1452019
The sigma-2 receptor and progesterone receptor membrane component 1 are different binding sites derived from independent genes
UB Chu, TA Mavlyutov, ML Chu, H Yang, A Schulman, C Mesangeau, ...
EBioMedicine 2 (11), 1806-1813, 2015
1112015
Investigation of the adrenergic and opioid binding affinities, metabolic stability, plasma protein binding properties, and functional effects of selected indole-based kratom …
S Obeng, SH Kamble, ME Reeves, LF Restrepo, A Patel, M Behnke, ...
Journal of medicinal chemistry 63 (1), 433-439, 2019
1082019
Suspected adulteration of commercial kratom products with 7-hydroxymitragynine
AG Lydecker, A Sharma, CR McCurdy, BA Avery, KM Babu, EW Boyer
Journal of Medical Toxicology 12, 341-349, 2016
1062016
Herbal medicines for the management of opioid addiction: safe and effective alternatives to conventional pharmacotherapy?
J Ward, C Rosenbaum, C Hernon, CR McCurdy, EW Boyer
CNS drugs 25, 999-1007, 2011
1062011
Phytochemical Characterization of the Leaves of Mitragyna Speciosa Grown in USA
F León, E Habib, JE Adkins, EB Furr, CR McCurdy, SJ Cutler
Natural Product Communications 4 (7), 1934578X0900400705, 2009
992009
Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis
L Garcés-Ramírez, JL Green, T Hiranita, TA Kopajtic, M Mereu, ...
Biological psychiatry 69 (3), 208-217, 2011
972011
New positron emission tomography (PET) radioligand for imaging σ-1 receptors in living subjects
ML James, B Shen, CL Zavaleta, CH Nielsen, C Mesangeau, PK Vuppala, ...
Journal of medicinal chemistry 55 (19), 8272-8282, 2012
952012
Kratom policy: the challenge of balancing therapeutic potential with public safety
WC Prozialeck, BA Avery, EW Boyer, O Grundmann, JE Henningfield, ...
International Journal of Drug Policy 70, 70-77, 2019
922019
Metabolite profiling and identification of enzymes responsible for the metabolism of mitragynine, the major alkaloid of Mitragyna speciosa (kratom)
SH Kamble, A Sharma, TI King, F León, CR McCurdy, BA Avery
Xenobiotica, 2019
882019
The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats
WC Hong, H Yano, T Hiranita, FT Chin, CR McCurdy, TP Su, SG Amara, ...
Journal of Biological Chemistry 292 (27), 11250-11261, 2017
872017
N-naphthoyl-β-naltrexamine (NNTA), a highly selective and potent activator of μ/κ-opioid heteromers
AS Yekkirala, MM Lunzer, CR McCurdy, MD Powers, AE Kalyuzhny, ...
Proceedings of the National Academy of Sciences 108 (12), 5098-5103, 2011
812011
Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents
AH Abdelazeem, SA Abdelatef, MT El-Saadi, HA Omar, SI Khan, ...
European Journal of Pharmaceutical Sciences 62, 197-211, 2014
802014
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