| Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study FE Dewey, MF Murray, JD Overton, L Habegger, JB Leader, SN Fetterolf, ... Science 354 (6319), aaf6814, 2016 | 547 | 2016 |
| Exome sequencing and analysis of 454,787 UK Biobank participants JD Backman, AH Li, A Marcketta, D Sun, J Mbatchou, MD Kessler, ... Nature 599 (7886), 628-634, 2021 | 441 | 2021 |
| Genetic identification of familial hypercholesterolemia within a single US health care system NS Abul-Husn, K Manickam, LK Jones, EA Wright, DN Hartzel, ... Science 354 (6319), aaf7000, 2016 | 419 | 2016 |
| Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of pathology K Burgos, I Malenica, R Metpally, A Courtright, B Rakela, T Beach, H Shill, ... PloS one 9 (5), e94839, 2014 | 403 | 2014 |
| Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing KL Burgos, A Javaherian, R Bomprezzi, L Ghaffari, S Rhodes, ... Rna 19 (5), 712-722, 2013 | 226 | 2013 |
| Exome sequencing–based screening for BRCA1/2 expected pathogenic variants among adult biobank participants K Manickam, AH Buchanan, MLB Schwartz, MLG Hallquist, JL Williams, ... JAMA Network Open 1 (5), e182140-e182140, 2018 | 197 | 2018 |
| Integrated genomic and epigenomic analysis of breast cancer brain metastasis B Salhia, J Kiefer, JTD Ross, R Metapally, RA Martinez, KN Johnson, ... PloS one 9 (1), e85448, 2014 | 160 | 2014 |
| Comparative proteome analysis of psychrophilic versus mesophilic bacterial species: Insights into the molecular basis of cold adaptation of proteins RPR Metpally, BVB Reddy BMC genomics 10, 1-10, 2009 | 158 | 2009 |
| Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation JR Homburger, EM Green, C Caleshu, MS Sunitha, RE Taylor, ... Proceedings of the National Academy of Sciences 113 (24), 6701-6706, 2016 | 118 | 2016 |
| The Caenorhabditis elegans Kinesin-3 Motor UNC-104/KIF1A Is Degraded upon Loss of Specific Binding to Cargo J Kumar, BC Choudhary, R Metpally, Q Zheng, ML Nonet, S Ramanathan, ... PLoS genetics 6 (11), e1001200, 2010 | 89 | 2010 |
| Comparison of analysis tools for miRNA high throughput sequencing using nerve crush as a model RPR Metpally, S Nasser, I Malenica, A Courtright, E Carlson, L Ghaffari, ... Frontiers in Genetics 4, 20, 2013 | 67 | 2013 |
| Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors RPR Metpally, R Sowdhamini BMC genomics 6, 1-20, 2005 | 67 | 2005 |
| OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica G Danks, C Campsteijn, M Parida, S Butcher, H Doddapaneni, B Fu, ... Nucleic acids research 41 (D1), D845-D853, 2013 | 62 | 2013 |
| Paired tumor and normal whole genome sequencing of metastatic olfactory neuroblastoma GJ Weiss, WS Liang, T Izatt, S Arora, I Cherni, RN Raju, G Hostetter, ... PloS one 7 (5), e37029, 2012 | 51 | 2012 |
| Familial hypocalciuric hypercalcemia type 1 and autosomal-dominant hypocalcemia type 1: prevalence in a large healthcare population R Dershem, CM Gorvin, RPR Metpally, S Krishnamurthy, DT Smelser, ... The American Journal of Human Genetics 106 (6), 734-747, 2020 | 50 | 2020 |
| Assessment of probable opioid use disorder using electronic health record documentation SA Palumbo, KM Adamson, S Krishnamurthy, S Manoharan, D Beiler, ... JAMA network open 3 (9), e2015909-e2015909, 2020 | 48 | 2020 |
| Modeling and analysis of MH1 domain of Smads and their interaction with promoter DNA sequence motif P Makkar, RPR Metpally, S Sangadala, BVB Reddy Journal of Molecular Graphics and Modelling 27 (7), 803-812, 2009 | 45 | 2009 |
| micro RNA changes in liver tissue associated with fibrosis progression in patients with hepatitis C KR Van Keuren‐Jensen, I Malenica, AL Courtright, LT Ghaffari, AP Starr, ... Liver International 36 (3), 334-343, 2016 | 44 | 2016 |
| Genome wide survey of G protein-coupled receptors in Tetraodon nigroviridis RPR Metpally, R Sowdhamini BMC evolutionary biology 5, 1-10, 2005 | 41 | 2005 |
| Molecular Interaction Between Smurfl WW2 Domain and PPXY Motifs of Smadl, Smad5, and Smad6—Modeling and Analysis S Sangadala, RP Rao Metpally, BV B. Reddy Journal of Biomolecular Structure and Dynamics 25 (1), 11-23, 2007 | 40 | 2007 |
David J CareyGeisingerVerified email at geisinger.edu
