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Nitu singh
Nitu singh
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α-Synuclein aggregation nucleates through liquid–liquid phase separation
S Ray, N Singh, R Kumar, K Patel, S Pandey, D Datta, J Mahato, ...
Nature chemistry 12 (8), 705-716, 2020
4862020
The structural basis of mode of activation and functional diversity: a case study with HtrA family of serine proteases
N Singh, RR Kuppili, K Bose
Archives of biochemistry and biophysics 516 (2), 85-96, 2011
842011
Glycosaminoglycans have variable effects on α-synuclein aggregation and differentially affect the activities of the resulting amyloid fibrils
S Mehra, D Ghosh, R Kumar, M Mondal, LG Gadhe, S Das, A Anoop, ...
Journal of Biological Chemistry 293 (34), 12975-12991, 2018
572018
Comparison of kinetics, toxicity, oligomer formation, and membrane binding capacity of α-synuclein familial mutations at the A53 site, including the newly discovered A53V mutation
GM Mohite, R Kumar, R Panigrahi, A Navalkar, N Singh, D Datta, S Mehra, ...
Biochemistry 57 (35), 5183-5187, 2018
492018
Dual regulatory switch confers tighter control on HtrA2 proteolytic activity
N Singh, A D'Souza, A Cholleti, GM Sastry, K Bose
The FEBS journal 281 (10), 2456-2470, 2014
392014
Allosteric regulation of serine protease HtrA2 through novel non-canonical substrate binding pocket
PR Bejugam, RR Kuppili, N Singh, N Gadewal, LK Chaganti, GM Sastry, ...
PloS one 8 (2), e55416, 2013
372013
Revolutionizing enzyme engineering through artificial intelligence and machine learning
N Singh, S Malik, A Gupta, KR Srivastava
Emerging Topics in Life Sciences 5 (1), 113-125, 2021
242021
Molecular basis of death effector domain chain assembly and its role in caspase‐8 activation
N Singh, A Hassan, K Bose
The FASEB Journal 30 (1), 186-200, 2016
242016
Liquid-liquid phase separation and liquid-to-solid transition mediate α-synuclein amyloid fibril containing hydrogel formation
S Ray, N Singh, S Pandey, R Kumar, L Gadhe, D Datta, K Patel, J Mahato, ...
bioRxiv, 619858, 2019
232019
α-Synuclein aggregation intermediates form fibril polymorphs with distinct prion-like properties
S Mehra, S Ahlawat, H Kumar, D Datta, A Navalkar, N Singh, K Patel, ...
Journal of Molecular Biology 434 (19), 167761, 2022
172022
Insights into the mechanism of human papillomavirus E2-induced procaspase-8 activation and cell death
N Singh, S Senapati, K Bose
Scientific reports 6 (1), 21408, 2016
122016
Apoptosis: pathways, molecules and beyond
N Singh, K Bose
Proteases in Apoptosis: Pathways, Protocols and Translational Advances, 1-30, 2015
112015
Cathepsins and HtrAs–multitasking proteases in programmed cell death
LK Chaganti, N Singh, K Bose
Proteases in Apoptosis: Pathways, Protocols and Translational Advances, 95-141, 2015
42015
Equilibrium dissociation and unfolding of human papillomavirus E2 transactivation domain
N Singh, S Kanthaje, K Bose
Biochemical and Biophysical Research Communications 463 (4), 496-503, 2015
12015
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Artikler 1–14