Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) N Tournier, L Chevillard, B Megarbane, S Pirnay, JM Scherrmann, ... International Journal of Neuropsychopharmacology 13 (7), 905-915, 2010 | 148 | 2010 |
Respiratory toxicity of buprenorphine results from the blockage of P-glycoprotein-mediated efflux of norbuprenorphine at the blood–brain barrier in mice H Alhaddad, S Cisternino, X Declèves, N Tournier, J Schlatter, F Chiadmi, ... Critical care medicine 40 (12), 3215-3223, 2012 | 80 | 2012 |
Preparation and stability of voriconazole eye drop solution A Dupuis, N Tournier, G Le Moal, N Venisse Antimicrobial agents and chemotherapy 53 (2), 798-799, 2009 | 79 | 2009 |
Simultaneous determination of eight β-lactam antibiotics, amoxicillin, cefazolin, cefepime, cefotaxime, ceftazidime, cloxacillin, oxacillin, and piperacillin, in human plasma … T Legrand, D Vodovar, N Tournier, N Khoudour, A Hulin Antimicrobial Agents and Chemotherapy 60 (8), 4734-4742, 2016 | 70 | 2016 |
Opioid transport by ATP-binding cassette transporters at the blood-brain barrier: implications for neuropsychopharmacology N Tournier, X Declèves, B Saubaméa, JM Scherrmann, S Cisternino Current pharmaceutical design 17 (26), 2829-2842, 2011 | 68 | 2011 |
Blood–brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P‐glycoprotein on a novel verapamil influx carrier H Chapy, B Saubaméa, N Tournier, F Bourasset, F Behar‐Cohen, ... British journal of pharmacology 173 (3), 497-510, 2016 | 65 | 2016 |
Imaging techniques to study drug transporter function in vivo N Tournier, B Stieger, O Langer Pharmacology & therapeutics 189, 104-122, 2018 | 61 | 2018 |
Effects of selected OATP and/or ABC transporter inhibitors on the brain and whole-body distribution of glyburide N Tournier, W Saba, S Cisternino, MA Peyronneau, A Damont, S Goutal, ... The AAPS journal 15, 1082-1090, 2013 | 60 | 2013 |
Transport of selected PET radiotracers by human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2): an in vitro screening N Tournier, H Valette, MA Peyronneau, W Saba, S Goutal, B Kuhnast, ... Journal of Nuclear Medicine 52 (3), 415-423, 2011 | 60 | 2011 |
Strategies to inhibit ABCB1-and ABCG2-mediated efflux transport of erlotinib at the blood–brain barrier: a PET study on nonhuman primates N Tournier, S Goutal, S Auvity, A Traxl, S Mairinger, T Wanek, OB Helal, ... Journal of Nuclear Medicine 58 (1), 117-122, 2017 | 54 | 2017 |
Imaging the impact of the P-glycoprotein (ABCB1) function on the brain kinetics of metoclopramide G Pottier, S Marie, S Goutal, S Auvity, MA Peyronneau, S Stute, ... Journal of Nuclear Medicine 57 (2), 309-314, 2016 | 52 | 2016 |
Physical blood-brain barrier disruption induced by focused ultrasound does not overcome the transporter-mediated efflux of erlotinib S Goutal, M Gerstenmayer, S Auvity, F Caillé, S Mériaux, I Buvat, B Larrat, ... Journal of controlled release 292, 210-220, 2018 | 51 | 2018 |
Repurposing radiotracers for myelin imaging: a study comparing 18F-florbetaben, 18F-florbetapir, 18F-flutemetamol, 11C-MeDAS, and 11C-PiB S Auvity, M Tonietto, F Caillé, B Bodini, M Bottlaender, N Tournier, ... European Journal of Nuclear Medicine and Molecular Imaging 47, 490-501, 2020 | 47 | 2020 |
Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model GL Roux, R Jarray, AC Guyot, S Pavoni, N Costa, F Théodoro, F Nassor, ... Scientific Reports 9 (1), 16310, 2019 | 46 | 2019 |
P-Glycoprotein (ABCB1) inhibits the influx and increases the efflux of 11C-metoclopramide across the blood–brain barrier: a PET study on nonhuman primates S Auvity, F Caillé, S Marie, C Wimberley, M Bauer, O Langer, I Buvat, ... Journal of Nuclear Medicine 59 (10), 1609-1615, 2018 | 45 | 2018 |
Impact of blood-brain barrier permeabilization induced by ultrasound associated to microbubbles on the brain delivery and kinetics of cetuximab: An immunoPET study using 89Zr … VL Tran, A Novell, N Tournier, M Gerstenmayer, A Schweitzer-Chaput, ... Journal of controlled release 328, 304-312, 2020 | 44 | 2020 |
Impact of P-glycoprotein function on the brain kinetics of the weak substrate 11C-metoclopramide assessed with PET imaging in humans N Tournier, M Bauer, V Pichler, L Nics, EM Klebermass, K Bamminger, ... Journal of Nuclear Medicine 60 (7), 985-991, 2019 | 38 | 2019 |
Validation of a simple HPLC-UV method for rifampicin determination in plasma: Application to the study of rifampicin arteriovenous concentration gradient S Goutal, S Auvity, T Legrand, F Hauquier, S Cisternino, H Chapy, ... Journal of Pharmaceutical and Biomedical Analysis 123, 173-178, 2016 | 37 | 2016 |
Discrepancies in the P-glycoprotein-Mediated Transport of 18F-MPPF: A Pharmacokinetic Study in Mice and Non-human Primates N Tournier, S Cisternino, MA Peyronneau, S Goutal, F Dolle, ... Pharmaceutical research 29, 2468-2476, 2012 | 34 | 2012 |
A proof-of-concept study to inhibit ABCG2-and ABCB1-mediated efflux transport at the human blood–brain barrier M Bauer, R Karch, B Wulkersdorfer, C Philippe, L Nics, EM Klebermass, ... Journal of Nuclear Medicine 60 (4), 486-491, 2019 | 31 | 2019 |