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Nicolas Tournier
Nicolas Tournier
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Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)
N Tournier, L Chevillard, B Megarbane, S Pirnay, JM Scherrmann, ...
International Journal of Neuropsychopharmacology 13 (7), 905-915, 2010
1482010
Respiratory toxicity of buprenorphine results from the blockage of P-glycoprotein-mediated efflux of norbuprenorphine at the blood–brain barrier in mice
H Alhaddad, S Cisternino, X Declèves, N Tournier, J Schlatter, F Chiadmi, ...
Critical care medicine 40 (12), 3215-3223, 2012
802012
Preparation and stability of voriconazole eye drop solution
A Dupuis, N Tournier, G Le Moal, N Venisse
Antimicrobial agents and chemotherapy 53 (2), 798-799, 2009
792009
Simultaneous determination of eight β-lactam antibiotics, amoxicillin, cefazolin, cefepime, cefotaxime, ceftazidime, cloxacillin, oxacillin, and piperacillin, in human plasma …
T Legrand, D Vodovar, N Tournier, N Khoudour, A Hulin
Antimicrobial Agents and Chemotherapy 60 (8), 4734-4742, 2016
702016
Opioid transport by ATP-binding cassette transporters at the blood-brain barrier: implications for neuropsychopharmacology
N Tournier, X Declèves, B Saubaméa, JM Scherrmann, S Cisternino
Current pharmaceutical design 17 (26), 2829-2842, 2011
682011
Blood–brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P‐glycoprotein on a novel verapamil influx carrier
H Chapy, B Saubaméa, N Tournier, F Bourasset, F Behar‐Cohen, ...
British journal of pharmacology 173 (3), 497-510, 2016
652016
Imaging techniques to study drug transporter function in vivo
N Tournier, B Stieger, O Langer
Pharmacology & therapeutics 189, 104-122, 2018
612018
Effects of selected OATP and/or ABC transporter inhibitors on the brain and whole-body distribution of glyburide
N Tournier, W Saba, S Cisternino, MA Peyronneau, A Damont, S Goutal, ...
The AAPS journal 15, 1082-1090, 2013
602013
Transport of selected PET radiotracers by human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2): an in vitro screening
N Tournier, H Valette, MA Peyronneau, W Saba, S Goutal, B Kuhnast, ...
Journal of Nuclear Medicine 52 (3), 415-423, 2011
602011
Strategies to inhibit ABCB1-and ABCG2-mediated efflux transport of erlotinib at the blood–brain barrier: a PET study on nonhuman primates
N Tournier, S Goutal, S Auvity, A Traxl, S Mairinger, T Wanek, OB Helal, ...
Journal of Nuclear Medicine 58 (1), 117-122, 2017
542017
Imaging the impact of the P-glycoprotein (ABCB1) function on the brain kinetics of metoclopramide
G Pottier, S Marie, S Goutal, S Auvity, MA Peyronneau, S Stute, ...
Journal of Nuclear Medicine 57 (2), 309-314, 2016
522016
Physical blood-brain barrier disruption induced by focused ultrasound does not overcome the transporter-mediated efflux of erlotinib
S Goutal, M Gerstenmayer, S Auvity, F Caillé, S Mériaux, I Buvat, B Larrat, ...
Journal of controlled release 292, 210-220, 2018
512018
Repurposing radiotracers for myelin imaging: a study comparing 18F-florbetaben, 18F-florbetapir, 18F-flutemetamol, 11C-MeDAS, and 11C-PiB
S Auvity, M Tonietto, F Caillé, B Bodini, M Bottlaender, N Tournier, ...
European Journal of Nuclear Medicine and Molecular Imaging 47, 490-501, 2020
472020
Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model
GL Roux, R Jarray, AC Guyot, S Pavoni, N Costa, F Théodoro, F Nassor, ...
Scientific Reports 9 (1), 16310, 2019
462019
P-Glycoprotein (ABCB1) inhibits the influx and increases the efflux of 11C-metoclopramide across the blood–brain barrier: a PET study on nonhuman primates
S Auvity, F Caillé, S Marie, C Wimberley, M Bauer, O Langer, I Buvat, ...
Journal of Nuclear Medicine 59 (10), 1609-1615, 2018
452018
Impact of blood-brain barrier permeabilization induced by ultrasound associated to microbubbles on the brain delivery and kinetics of cetuximab: An immunoPET study using 89Zr …
VL Tran, A Novell, N Tournier, M Gerstenmayer, A Schweitzer-Chaput, ...
Journal of controlled release 328, 304-312, 2020
442020
Impact of P-glycoprotein function on the brain kinetics of the weak substrate 11C-metoclopramide assessed with PET imaging in humans
N Tournier, M Bauer, V Pichler, L Nics, EM Klebermass, K Bamminger, ...
Journal of Nuclear Medicine 60 (7), 985-991, 2019
382019
Validation of a simple HPLC-UV method for rifampicin determination in plasma: Application to the study of rifampicin arteriovenous concentration gradient
S Goutal, S Auvity, T Legrand, F Hauquier, S Cisternino, H Chapy, ...
Journal of Pharmaceutical and Biomedical Analysis 123, 173-178, 2016
372016
Discrepancies in the P-glycoprotein-Mediated Transport of 18F-MPPF: A Pharmacokinetic Study in Mice and Non-human Primates
N Tournier, S Cisternino, MA Peyronneau, S Goutal, F Dolle, ...
Pharmaceutical research 29, 2468-2476, 2012
342012
A proof-of-concept study to inhibit ABCG2-and ABCB1-mediated efflux transport at the human blood–brain barrier
M Bauer, R Karch, B Wulkersdorfer, C Philippe, L Nics, EM Klebermass, ...
Journal of Nuclear Medicine 60 (4), 486-491, 2019
312019
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