| Inhibition of resistance-refractory P. falciparum kinase PKG delivers prophylactic, blood stage, and transmission-blocking antiplasmodial activity M Vanaerschot, JM Murithi, CFA Pasaje, S Ghidelli-Disse, L Dwomoh, ... Cell chemical biology 27 (7), 806-816. e8, 2020 | 61 | 2020 |
| From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease AJH Brown, SJ Bradley, FH Marshall, GA Brown, KA Bennett, J Brown, ... Cell 184 (24), 5886-5901. e22, 2021 | 48 | 2021 |
| Thiodiglycolic acid is excreted by humans receiving ifosfamide and inhibits mitochondrial function in rats TM Visarius, H Bähler, A Küpfer, T Cerny, BH Lauterburg Drug Metabolism and Disposition 26 (3), 193-196, 1998 | 48 | 1998 |
| Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs SJ Bradley, C Molloy, P Valuskova, L Dwomoh, M Scarpa, M Rossi, ... Nature chemical biology 16 (3), 240-249, 2020 | 43 | 2020 |
| Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes SJ Bradley, C Molloy, C Bundgaard, AJ Mogg, KJ Thompson, L Dwomoh, ... Molecular pharmacology 93 (6), 645-656, 2018 | 28 | 2018 |
| Targeting the M1 muscarinic acetylcholine receptor in Alzheimer’s disease L Dwomoh, GS Tejeda, AB Tobin Neuronal Signaling 6 (1), NS20210004, 2022 | 20 | 2022 |
| Variants of the EAAT2 Glutamate Transporter Gene Promoter Are Associated with Cerebral Palsy in Preterm Infants S Rajatileka, D Odd, MT Robinson, AC Spittle, L Dwomoh, M Williams, ... Molecular Neurobiology 55, 2013-2024, 2018 | 20 | 2018 |
| Selective phosphorylation of threonine residues defines GPR84–arrestin interactions of biased ligands S Marsango, RJ Ward, L Jenkins, AJ Butcher, Z Al Mahmud, L Dwomoh, ... Journal of Biological Chemistry 298 (5), 2022 | 13 | 2022 |
| Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease M Scarpa, C Molloy, L Jenkins, B Strellis, RF Budgett, S Hesse, ... Proceedings of the National Academy of Sciences 118 (50), e2107389118, 2021 | 13 | 2021 |
| M1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease L Dwomoh, M Rossi, M Scarpa, E Khajehali, C Molloy, P Herzyk, ... Science Signaling 15 (760), eabm3720, 2022 | 5 | 2022 |
| Activation of M1 muscarinic receptors reduce pathology and slow progression of neurodegenerative disease L Dwomoh, M Rossi, M Scarpa, E Khajehali, C Molloy, P Herzyk, ... bioRxiv, 2021.07. 30.454298, 2021 | 4 | 2021 |
| Host tissue proteomics reveal insights into the molecular basis of Schistosoma haematobium-induced bladder pathology DNM Osakunor, K Ishida, OK Lamanna, M Rossi, L Dwomoh, MH Hsieh PLoS Neglected Tropical Diseases 16 (2), e0010176, 2022 | 3 | 2022 |
| Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner N Barki, L Jenkins, S Marsango, D Dedeo, D Bolognini, L Dwomoh, ... Elife 12, RP91861, 2023 | | 2023 |
| Characterising the signal transduction pathway of mGlu (5) to determine the role of receptor phosphorylation B Strellis, L Wei, L Dwomoh, S Bradley, B Hudson BRITISH JOURNAL OF PHARMACOLOGY 180 (4), 499-499, 2023 | | 2023 |
| Phosphorylation of the M1 muscarinic acetylcholine receptor mediates protection in neurodegenerative disease M Scarpa, C Molloy, L Jenkins, G Tejeda, M Rossi, L Dwomoh, ... bioRxiv, 2021.04. 29.440753, 2021 | | 2021 |
| Investigating protein expression, modifications and interactions in the brain: Protocol for preparing rodent brain tissue for mass spectrometry-based quantitative-and phospho … L Dwomoh Methods in Cell Biology 166, 251-269, 2021 | | 2021 |
| Hippocampal proteomics of mouse prion disease: unravelling disease networks and understanding the mechanism of disease-modifying ligands L Dwomoh, M Rossi, A Bottrill, S Bradley, A Tobin FEBS OPEN BIO 9, 223-223, 2019 | | 2019 |
| The Role of β-cell Glutamate Receptors in Pancreatic Endocrine Function and in the Pathogenesis of Type 1 Diabetes Mellitus L Dwomoh University of Bristol, 2016 | | 2016 |
| Molecular composition, function and physiology of Kainate Receptors (KARs) in pancreatic endocrine cells L Dwomoh, G Whitehead, A Spittle, E Molnar, A Varadi FEBS JOURNAL 282, 137-138, 2015 | | 2015 |
| Efecto de la cascarilla café sobre la lipotoxicidad en células pancreáticas B Fernández, L Dwomoh, MD Mesa, A Varadi, M Castillo | | |
