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Blanchard Valentin
Blanchard Valentin
Department of Medicine, Centre for Heart Lung Innovation, Providence Healthcare Research Institute
Adresse e-mail validée de hli.ubc.ca
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Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor) Implications for the Efficacy of Evolocumab
A Thedrez, DJ Blom, S Ramin-Mangata, V Blanchard, M Croyal, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (3), 592-598, 2018
892018
PCSK9 inhibition with alirocumab reduces lipoprotein (a) levels in nonhuman primates by lowering apolipoprotein (a) production rate
M Croyal, TTT Tran, RH Blanchard, JC Le Bail, EF Villard, B Poirier, ...
Clinical Science 132 (10), 1075-1083, 2018
452018
VLDL (very-low-density lipoprotein)-Apo E (apolipoprotein E) may influence Lp (a)(lipoprotein [a]) synthesis or assembly
M Croyal, V Blanchard, K Ouguerram, M Chétiveaux, L Cabioch, T Moyon, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 40 (3), 819-829, 2020
332020
PCSK9: from biology to clinical applications
V Blanchard, I Khantalin, S Ramin-Mangata, K Chémello, B Nativel, ...
Pathology 51 (2), 177-183, 2019
332019
Kinetics of plasma apolipoprotein E isoforms by LC-MS/MS: a pilot study
V Blanchard, S Ramin-Mangata, S Billon-Crossouard, A Aguesse, ...
Journal of Lipid Research 59 (5), 892-900, 2018
282018
A high-throughput mass spectrometry-based assay for large-scale profiling of circulating human apolipoproteins [S]
V Blanchard, D Garçon, C Jaunet, K Chemello, S Billon-Crossouard, ...
Journal of Lipid Research 61 (7), 1128-1139, 2020
272020
The size of apolipoprotein (a) is an independent determinant of the reduction in lipoprotein (a) induced by PCSK9 inhibitors
V Blanchard, K Chemello, T Hollstein, CC Hong-Fong, F Schumann, ...
Cardiovascular Research 118 (9), 2103-2111, 2022
252022
Lipoprotein (a) cellular uptake ex vivo and hepatic capture in vivo is insensitive to PCSK9 inhibition with alirocumab
K Chemello, S Beeské, TT Trang Tran, V Blanchard, EF Villard, B Poirier, ...
Basic to Translational Science 5 (6), 549-557, 2020
252020
Effects of proprotein convertase subtilisin kexin type 9 modulation in human pancreatic beta cells function
S Ramin-Mangata, A Thedrez, B Nativel, N Diotel, V Blanchard, M Wargny, ...
Atherosclerosis 326, 47-55, 2021
222021
Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes
S Ramin-Mangata, M Wargny, M Pichelin, C Le May, A Thédrez, ...
Atherosclerosis 293, 49-56, 2020
222020
Smooth Muscle Cell—Macrophage Interactions Leading to Foam Cell Formation in Atherosclerosis: Location, Location, Location
P Xiang, V Blanchard, GA Francis
Frontiers in Physiology 13, 921597, 2022
182022
Macrophages in atherosclerosis, first or second row players?
E Checkouri, V Blanchard, O Meilhac
Biomedicines 9 (9), 1214, 2021
142021
Stable isotope kinetic study of ApoM (apolipoprotein M)
M Croyal, S Billon-Crossouard, S Goulitquer, A Aguesse, L León, F Fall, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 38 (1), 255-261, 2018
132018
Plasma apolipoprotein concentrations and incident diabetes in subjects with prediabetes
M Croyal, M Wargny, K Chemello, C Chevalier, V Blanchard, ...
Cardiovascular Diabetology 21 (1), 21, 2022
122022
Plasma concentrations of lipoproteins and risk of lower-limb peripheral artery disease in people with type 2 diabetes: the SURDIAGENE study
C Bertrand, PJ Saulnier, L Potier, M Croyal, V Blanchard, E Gand, ...
Diabetologia 64, 668-680, 2021
122021
Key aspects of PCSK9 inhibition beyond LDL lowering
S Ramin-Mangata, V Blanchard, G Lambert
Current Opinion in Lipidology 29 (6), 453-458, 2018
112018
Genome-wide characterization of a highly penetrant form of hyperlipoprotein (a) emia associated with genetically elevated cardiovascular risk
S Coassin, K Chemello, I Khantalin, L Forer, P Döttelmayer, S Schönherr, ...
Circulation: Genomic and Precision Medicine 15 (2), e003489, 2022
82022
Lysosomal acid lipase deficiency: A rare inherited dyslipidemia but potential ubiquitous factor in the development of atherosclerosis and fatty liver disease
KJ Besler, V Blanchard, GA Francis
Frontiers in Genetics 13, 1013266, 2022
62022
Reduced lipoprotein (a) associated with the apolipoprotein E2 genotype confers cardiovascular protection in familial hypercholesterolemia
V Blanchard, M Croyal, I Khantalin, S Ramin-Mangata, K Chemello, ...
JACC: Basic to Translational Science 4 (3), 425-427, 2019
62019
Homozygous FH patients with identical mutations variably express the LDL receptor: implications for the efficacy of evolocumab
A Thedrez, DJ Blom, S Ramin-Mangata, V Blanchard, M Croyal, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (3), 592, 2018
52018
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