| Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo JA Zuris, DB Thompson, Y Shu, JP Guilinger, JL Bessen, JH Hu, ... Nature biotechnology 33 (1), 73-80, 2015 | 1508 | 2015 |
| Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification JP Guilinger, DB Thompson, DR Liu Nature biotechnology 32 (6), 577-582, 2014 | 1176 | 2014 |
| Initial performance of the NEOWISE reactivation mission A Mainzer, J Bauer, RM Cutri, T Grav, J Masiero, R Beck, P Clarkson, ... The Astrophysical Journal 792 (1), 30, 2014 | 589 | 2014 |
| Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents X Gao, Y Tao, V Lamas, M Huang, WH Yeh, B Pan, YJ Hu, JH Hu, ... Nature 553 (7687), 217-221, 2018 | 531 | 2018 |
| Small molecule–triggered Cas9 protein with improved genome-editing specificity KM Davis, V Pattanayak, DB Thompson, JA Zuris, DR Liu Nature chemical biology 11 (5), 316-318, 2015 | 487 | 2015 |
| Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins BR McNaughton, JJ Cronican, DB Thompson, DR Liu Proceedings of the National Academy of Sciences 106 (15), 6111-6116, 2009 | 327 | 2009 |
| Potent Delivery of Functional Proteins into Mammalian Cells in Vitro and in Vivo Using a Supercharged Protein JJ Cronican, DB Thompson, KT Beier, BR McNaughton, CL Cepko, ... ACS chemical biology 5 (8), 747-752, 2010 | 257 | 2010 |
| Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier LM Yonker, T Gilboa, AF Ogata, Y Senussi, R Lazarovits, BP Boribong, ... The Journal of Clinical Investigation 131 (14), 2021 | 213 | 2021 |
| Engineering and identifying supercharged proteins for macromolecule delivery into mammalian cells DB Thompson, JJ Cronican, DR Liu Methods in enzymology 503, 293-319, 2012 | 158 | 2012 |
| Comparison of genome screens for two independent cohorts provides replication of suggestive linkage of bone mineral density to 3p21 and 1p36 SG Wilson, PW Reed, A Bansal, M Chiano, M Lindersson, M Langdown, ... The American Journal of Human Genetics 72 (1), 144-155, 2003 | 157 | 2003 |
| Cellular uptake mechanisms and endosomal trafficking of supercharged proteins DB Thompson, R Villaseñor, BM Dorr, M Zerial, DR Liu Chemistry & biology 19 (7), 831-843, 2012 | 155 | 2012 |
| Cas9-FokI fusion proteins and uses thereof DR Liu, JP Guilinger, DB Thompson US Patent 9,322,037, 2016 | 154 | 2016 |
| A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells B Chaikind, JL Bessen, DB Thompson, JH Hu, DR Liu Nucleic acids research 44 (20), 9758-9770, 2016 | 145 | 2016 |
| Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo M Li, Y Tao, Y Shu, JR LaRochelle, A Steinauer, D Thompson, ... Journal of the American Chemical Society 137 (44), 14084-14093, 2015 | 141 | 2015 |
| Cas9-recombinase fusion proteins and uses thereof DR Liu, JP Guilinger, DB Thompson US Patent 9,388,430, 2016 | 135 | 2016 |
| Ultrathin ferroic HfO2–ZrO2 superlattice gate stack for advanced transistors SS Cheema, N Shanker, LC Wang, CH Hsu, SL Hsu, YH Liao, ... Nature 604 (7904), 65-71, 2022 | 134 | 2022 |
| A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo JJ Cronican, KT Beier, TN Davis, JC Tseng, W Li, DB Thompson, AF Shih, ... Chemistry & biology 18 (7), 833-838, 2011 | 134 | 2011 |
| Use of cationic lipids to deliver CAS9 DR Liu, JA Zuris, DB Thompson US Patent 9,737,604, 2017 | 128 | 2017 |
| Delivery system for functional nucleases DR Liu, JA Zuris, DB Thompson US Patent 9,526,784, 2016 | 123 | 2016 |
| Supercharged proteins for cell penetration DR Liu, BR McNaughton, JJ Cronican, DB Thompson US Patent App. 12/989,829, 2011 | 120* | 2011 |
David R. LiuHarvard UniversityVerified email at fas.harvard.edu
