| Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release Y Suofu, W Li, FG Jean-Alphonse, J Jia, NK Khattar, J Li, SV Baranov, ... Proceedings of the National Academy of Sciences 114 (38), E7997-E8006, 2017 | 403 | 2017 |
| Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease J Kim, JP Moody, CK Edgerly, OL Bordiuk, K Cormier, K Smith, MF Beal, ... Human molecular genetics 19 (20), 3919-3935, 2010 | 389 | 2010 |
| In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease … M Faideau, J Kim, K Cormier, R Gilmore, M Welch, G Auregan, N Dufour, ... Human molecular genetics 19 (15), 3053-3067, 2010 | 340 | 2010 |
| Inhibition of mitochondrial protein import by mutant huntingtin H Yano, SV Baranov, OV Baranova, J Kim, Y Pan, S Yablonska, ... Nature neuroscience 17 (6), 822-831, 2014 | 224 | 2014 |
| The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington’s disease mouse models V Chopra, L Quinti, J Kim, L Vollor, KL Narayanan, C Edgerly, ... Cell reports 2 (6), 1492-1497, 2012 | 211 | 2012 |
| Distinct roles of lymphotoxin α and the type I tumor necrosis factor (TNF) receptor in the establishment of follicular dendritic cells from non–bone marrow–derived cells M Matsumoto, YX Fu, H Molina, G Huang, J Kim, DA Thomas, MH Nahm, ... The Journal of experimental medicine 186 (12), 1997-2004, 1997 | 176 | 1997 |
| Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease G Keryer, JR Pineda, G Liot, J Kim, P Dietrich, C Benstaali, K Smith, ... The Journal of clinical investigation 121 (11), 4372-4382, 2011 | 173 | 2011 |
| Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral … Y Zhang, A Cook, J Kim, SV Baranov, J Jiang, K Smith, K Cormier, ... Neurobiology of disease 55, 26-35, 2013 | 134 | 2013 |
| Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice SJ Del Signore, DJ Amante, J Kim, EC Stack, S Goodrich, K Cormier, ... Amyotrophic Lateral Sclerosis 10 (2), 85-94, 2009 | 123 | 2009 |
| Melatonin inhibits cytosolic mitochondrial DNA–induced neuroinflammatory signaling in accelerated aging and neurodegeneration A Jauhari, SV Baranov, Y Suofu, J Kim, T Singh, S Yablonska, F Li, ... The Journal of clinical investigation 130 (6), 3124-3136, 2020 | 120 | 2020 |
| MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition DM Taylor, R Moser, E Régulier, L Breuillaud, M Dixon, AA Beesen, ... Journal of Neuroscience 33 (6), 2313-2325, 2013 | 117 | 2013 |
| Mutant huntingtin disrupts mitochondrial proteostasis by interacting with TIM23 S Yablonska, V Ganesan, LM Ferrando, JH Kim, A Pyzel, OV Baranova, ... Proceedings of the National Academy of Sciences 116 (33), 16593-16602, 2019 | 77 | 2019 |
| Therapeutic attenuation of mitochondrial dysfunction and oxidative stress in neurotoxin models of Parkinson's disease EC Stack, JL Ferro, J Kim, SJ Del Signore, S Goodrich, S Matson, BB Hunt, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1782 (3), 151-162, 2008 | 72 | 2008 |
| Time course of cerebrospinal fluid inflammatory biomarkers and relationship to 6-month neurologic outcome in adult severe traumatic brain injury EL Nwachuku, AM Puccio, A Adeboye, YF Chang, J Kim, DO Okonkwo Clinical neurology and neurosurgery 149, 1-5, 2016 | 65 | 2016 |
| Reduced creatine kinase as a central and peripheral biomarker in Huntington's disease J Kim, DJ Amante, JP Moody, CK Edgerly, OL Bordiuk, K Smith, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (7-8 …, 2010 | 58 | 2010 |
| Mitochondrial nuclear receptors and transcription factors: who's minding the cell? J Lee, S Sharma, J Kim, RJ Ferrante, H Ryu Journal of neuroscience research 86 (5), 961-971, 2008 | 55 | 2008 |
| Monoallele deletion of CBP leads to pericentromeric heterochromatin condensation through ESET expression and histone H3 (K9) methylation J Lee, S Hagerty, KA Cormier, J Kim, AL Kung, RJ Ferrante, H Ryu Human molecular genetics 17 (12), 1774-1782, 2008 | 53 | 2008 |
| ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: potential application … T Chen, R Benmohamed, J Kim, K Smith, D Amante, RI Morimoto, ... Journal of medicinal chemistry 55 (1), 515-527, 2012 | 52 | 2012 |
| The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity C Tourette, F Farina, RP Vazquez-Manrique, AM Orfila, J Voisin, ... PLoS biology 12 (6), e1001895, 2014 | 51 | 2014 |
| Pyrimidine-2, 4, 6-trione derivatives and their inhibition of mutant SOD1-dependent protein aggregation. Toward a treatment for amyotrophic lateral sclerosis G Xia, R Benmohamed, J Kim, AC Arvanites, RI Morimoto, RJ Ferrante, ... Journal of medicinal chemistry 54 (7), 2409-2421, 2011 | 51 | 2011 |
