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Alexandre Dubrac
Alexandre Dubrac
Adresse e-mail validée de umontreal.ca
Titre
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Année
FGF-dependent metabolic control of vascular development
P Yu, K Wilhelm, A Dubrac, JK Tung, TC Alves, JS Fang, Y Xie, J Zhu, ...
Nature 545 (7653), 224-228, 2017
3102017
Lacteal junction zippering protects against diet-induced obesity
F Zhang, G Zarkada, J Han, J Li, A Dubrac, R Ola, G Genet, K Boyé, ...
Science 361 (6402), 599-603, 2018
1842018
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch
IM Aspalter, E Gordon, A Dubrac, A Ragab, J Narloch, P Vizán, I Geudens, ...
Nature communications 6 (1), 7264, 2015
1782015
Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization
N Rama, A Dubrac, T Mathivet, RA Ní Chárthaigh, G Genet, B Cristofaro, ...
Nature medicine 21 (5), 483-491, 2015
1642015
Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia
N Baeyens, B Larrivée, R Ola, B Hayward-Piatkowskyi, A Dubrac, ...
Journal of Cell Biology 214 (7), 807-816, 2016
1572016
PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia
R Ola, A Dubrac, J Han, F Zhang, JS Fang, B Larrivée, M Lee, AA Urarte, ...
Nature communications 7 (1), 13650, 2016
1542016
PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells
AA Lanahan, D Lech, A Dubrac, J Zhang, ZW Zhuang, A Eichmann, ...
Circulation 130 (11), 902-909, 2014
1122014
SMAD4 prevents flow induced arteriovenous malformations by inhibiting casein kinase 2
R Ola, SH Künzel, F Zhang, G Genet, R Chakraborty, L Pibouin-Fragner, ...
Circulation 138 (21), 2379-2394, 2018
932018
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition
S Crespo-Garcia, PR Tsuruda, A Dejda, RD Ryan, F Fournier, SY Chaney, ...
Cell metabolism 33 (4), 818-832. e7, 2021
912021
Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis
G Genet, K Boyé, T Mathivet, R Ola, F Zhang, A Dubrac, J Li, N Genet, ...
Nature communications 10 (1), 2350, 2019
762019
Targeting NCK-mediated endothelial cell front-rear polarity inhibits neovascularization
A Dubrac, G Genet, R Ola, F Zhang, L Pibouin-Fragner, J Han, J Zhang, ...
Circulation 133 (4), 409-421, 2016
752016
NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy
A Dubrac, SE Künzel, SH Künzel, J Li, RR Chandran, K Martin, DM Greif, ...
Nature communications 9 (1), 3463, 2018
672018
Stabilization of the G-quadruplex at the VEGF IRES represses cap-independent translation
A Cammas, A Dubrac, B Morel, A Lamaa, C Touriol, MP Teulade-Fichou, ...
RNA biology 12 (3), 320-329, 2015
652015
Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis
L Nie, X Guo, L Esmailzadeh, J Zhang, A Asadi, M Collinge, X Li, JD Kim, ...
The Journal of clinical investigation 123 (12), 5082-5097, 2013
612013
Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation
G Zarkada, JP Howard, X Xiao, H Park, M Bizou, S Leclerc, SE Künzel, ...
Developmental cell 56 (15), 2237-2251. e6, 2021
592021
Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity
A Jabouille, M Delugin, R Pineau, A Dubrac, F Soulet, S Lhomond, ...
Oncotarget 6 (28), 24922, 2015
552015
The nonlysosomal β‐glucosidase GBA2 promotes endoplasmic reticulum stress and impairs tumorigenicity of human melanoma cells
SC Sorli, S Colié, V Albinet, A Dubrac, C Touriol, N Guilbaud, C Bedia, ...
The FASEB Journal 27 (2), 489-498, 2013
512013
The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization
F Zhang, C Prahst, T Mathivet, L Pibouin-Fragner, J Zhang, G Genet, ...
Nature communications 7 (1), 13517, 2016
502016
Functional divergence between 2 chemokines is conferred by single amino acid change
A Dubrac, C Quemener, E Lacazette, F Lopez, C Zanibellato, WG Wu, ...
Blood, The Journal of the American Society of Hematology 116 (22), 4703-4711, 2010
472010
PERK mediates the IRES-dependent translational activation of mRNAs encoding angiogenic growth factors after ischemic stress
C Philippe, A Dubrac, C Quelen, A Desquesnes, L Van Den Berghe, ...
Science signaling 9 (426), ra44-ra44, 2016
452016
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